Generation of recombinant fragments of CD11b expressing the functional β-glucan-binding lectin site of CR3 (CD11b/CD18)

Journal of Immunology

Volumn 162, Issue 12, 1999, Pages 7285-7293

  Xia, Yu ^a   Ross, Gordon D ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCAN; CD11B ANTIGEN; CELL ADHESION MOLECULE; EPITOPE; INTEGRIN; LECTIN; OPSONIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CYTOTOXICITY; FLOW CYTOMETRY; IMMUNOBLOTTING; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BINDING SITES; CARRIER PROTEINS; EPITOPES; FLOW CYTOMETRY; GENETIC VECTORS; HUMANS; LECTINS; MACROPHAGE-1 ANTIGEN; NEUTROPHILS; PEPTIDE FRAGMENTS; RADIOLIGAND ASSAY; RECOMBINANT PROTEINS; SPODOPTERA;

EID: 0033564269     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Springer, T., G. Galfre, D. S. Secher, and C. Milstein. 1979. Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur. J. Immunol. 9:301.
2. Beller, D. I., T. A. Springer, and R. D. Schreiber. 1982. Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor. J. Exp. Med. 156:1000.
3. Anderson, D. C., L. J. Miller, F. C. Schmalstieg, R. Rothlein, and T. A. Springer. 1986. Contributions of the Mac-1 glycoprotein family to adherence-dependent granulocyte functions: structure-function assessments employing subunit-specific monoclonal antibodies. J. Immunol. 137:15.
4. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301.
5. Hogg, N., and C. Berlin. 1995. Structure and function of adhesion receptors in leukocyte trafficking. Immunol. Today 16:327.
6. Sugimori, T., D. L. Griffith, and M. A. Arnaout. 1997. Emerging paradigms of integrin ligand binding and activation. Kidney Int. 51:1454.
7. Sutterwala, F. S., L. A. Rosenthal, and D. M. Mosser. 1996. Cooperation between CR1 (CD35) and CR3 (CD11b/CD18) in the binding of complement-opsonized particles. J. Leukocyte Biol. 59:883.
8. Xia, Y., and G. D. Ross. 1999. Roles of the integrins CR3 and CR4 in disease and therapeutic strategies. In Therapeutic Interventions in the Complement System. V. M. Holers and J. D. Lambris, eds. Humana Press, Totowa, NJ, In press.
9. Xia, Y., and G. D. Ross. 1999. CR3. In Complement FactsBook, B. J. Morley and M. J. Walport, eds. Academic Press, London, In press.
10. Brown, E., and N. Hogg. 1996. Where the outside meets the inside: Integrins as activators and targets of signal transduction cascades. Immunol. Lett. 54:189.
11. Newton, R. A., M. Thiel, and N. Hogg. 1997. Signaling mechanisms and the activation of leukocyte integrins. J. Leukocyte Biol. 61:422.
12. 3) has lectin-like properties analogous to bovine conglutinin and functions as a receptor for zymosan and rabbit erythrocytes as well as a receptor for iC3b. J. Immunol. 134:3307.
13. Ross, G. D., R. A. Thompson, M. J. Walport, T. A. Springer, J. V. Watson, R. H. R. Ward, J. Lida, S. L. Newman, R. A. Harrison, and P. J. Lachmann. 1985. Characterization of patients with an increased susceptibility to bacterial infections and a genetic deficiency of leukocyte membrane complement receptor type 3 and the related membrane antigen LFA-1. Blood 66:882.
14. 3) for β-glucans. Complement Inflamm. 4:61.
15. Cain, J. A., S. L. Newman, and G. D. Ross. 1987. Role of complement receptor type three and serum opsonins in the neutrophil response to yeast. Complement Inflamm. 4:75.
16. Perlmann, P., H. Perlmann, and H. J. Müller-Eberhard. 1975. Cytolytic lymphocytic cells with complement receptor in human blood: induction of cytolysis by IgG antibody but not by target cell-bound C3. J. Exp. Med. 141:287.
17. Ehlenberger, A. G., and V. Nussenzweig. 1977. The role of membrane receptors for C3b and C3d in phagocytosis. J. Exp. Med. 145:357.
18. Wright, S. D., and S. C. Silverstein. 1982. Tumor-promoting phorbol esters stimulate C3b and C3b′ receptor-mediated phagocytosis in cultured human monocytes. J. Exp. Med. 156:1149.
19. Wright, S. D. 1985. Cellular strategies in receptor-mediated phagocytosis. Rev. Infect. Dis. 7:395.
20. Větvička, V., B. P. Thornton, and G. D. Ross. 1996. Soluble β-glucan polysaccharide binding to the lectin site of neutrophil or NK cell complement receptor type 3 (CD11b/CD18) generates a primed state of the receptor capable of mediating cytotoxicity of iC3b-opsonized target cells. J. Clin. Invest. 98:50.
21. Xia, Y., V. Větvička, J. Yan, M. Hanikýřová, T. N. Mayadas, and G. D. Ross. 1999. The β-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells. J. Immunol. 162:2281.
22. Větvička, V., B. P. Thornton, T. J. Wieman, and G. D. Ross. 1997. Targeting of NK cells to mammary carcinoma via naturally occurring tumor cell-bound iC3b and β-glucan-primed CR3 (CD11b/CD18). J. Immunol. 159:599.
23. Ross, G. D., V. Větvička, J. Yan, Y. Xia, and J. Větvičková. 1999. Therapeutic intervention with complement and β-glucan in cancer. Immunopharmacology. In press.
24. Weis, W. I., M. E. Taylor, and K. Drickamer. 1998. The C-type lectin superfamily in the immune system. Immunol. Rev. 163:19.
25. Thornton, B. P., V. Větvička, M. Pitman, R. C. Goldman, and G. D. Ross. 1996. Analysis of the sugar specificity and molecular location of the β-glucan-binding lectin site of complement receptor type 3 (CD11b/CD18). J. Immunol. 156:1235.
26. Forsyth, C. B., E. F. Plow, and L. Zhang. 1998. Interaction of the fungal pathogen Candida albicans with integrin CD11b/CD18: recognition by the I domain is modulated by the lectin-like domain and the CD18 subunit. J. Immunol. 161: 6198.
27. Petty, H. R., and R. F. Todd, III. 1996. Integrins as promiscuous signal transduction devices. Immunol. Today 17:209.
28. Todd, R. F., III and H. R. Petty. 1997. β2(CD11/CD18) integrins can serve as signaling partners for other leukocyte receptors. J. Lab. Clin. Med. 129:492.
29. Sehgal, G., K. Zhang, R. F. Todd, III, L. A. Boxer, and H. R. Petty. 1993. Lectin-like inhibition of immune complex receptor-mediated stimulation of neutrophils: effects on cytosolic calcium release and superoxide production. J. Immunol. 150:4571.
30. Zhou, M., R. F. Todd III, J. G. J. Van de Winkel, and H. R. Petty. 1993. Co-capping of the leukoadhesin molecules complement receptor type 3 and lymphocyte function-associated antigen-1 with Fcγ receptor III on human neutrophils: possible role of lectin-like interactions. J. Immunol. 150:3030.
31. Krauss, J. C., H. Poo, W. Xue, L. Mayo-Bond, R. F. Todd III, and H. R. Petty. 1994. Reconstitution of antibody-dependent phagocytosis in fibroblasts expressing Fcγ receptor IIIB and the complement receptor type 3. J. Immunol. 153:1769.
32. Xue, W., A. L. Kindzelskii, R. F. Todd III, and H. R. Petty. 1994. Physical association of complement receptor type 3 and urokinase-type plasminogen activator receptor in neutrophil membranes. J. Immunol. 152:4630.
33. Gyetko, M. R., R. G. Sitrin, J. A. Fuller, R. F. Todd III, H. Petty, and T. J. Standiford. 1995. Function of the urokinase receptor (CD87) in neutrophil chemotaxis. J. Leukocyte Biol. 58:533.
34. Sitrin, R. G., R. F. Todd III, H. R. Petty, T. G. Brock, S. B. Shollenberger, E. Albrecht, and M. R. Gyetko. 1996. The urokinase receptor (CD87) facilitates CD11b/CD18-mediated adhesion of human monocytes. J. Clin. Invest. 97:1942.
35. Wong, W. S. F., D. I. Simon, P. M. Rosoff, N. K. Rao, and H. A. Chapman. 1996. Mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: role of Mac-1(CD11b/CD18) and urokinase receptor (CD87). Immunology 88:90.
36. Cramer, R., M. Pausa, F. Rapagna, and F. Tedesco. 1998. Cross-linking of CD59 promotes CR3 dependent adherence of PMN to fibronectin and endothelial cells. Mol. Immunol. 35:407.
37. 2 integrins in vivo. J. Exp. Med. 188:1029.
38. 2) and urokinase receptors on migrating neutrophils. Biophys. J. 73:1777.
39. Petty, H. R., A. L. Kindzelskii, Y. Adachi, and R. F. Todd III. 1997. Ectodomain interactions of leukocyte integrins and pro-inflammatory GPI-linked membrane proteins. J. Pharmacol. Biomed. Anal. 15:1405.
40. Eddy, A., S. L. Newman, F. Cosio, T. LeBien, and A. Michael. 1984. The distribution of the CR3 receptor on human cells and tissue as revealed by a monoclonal antibody. Clin. Immunol. Immunopathol. 31:371.
41. Diamond, M. S., J. Garcia-Aguilar, J. K. Bickford, A. L. Corbi, and T. A. Springer. 1993. The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. J. Cell Biol. 120:1031.
42. Phillips, J. H., J. E. Gumperz, P. Parham, and L. L. Lanier. 1995. Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes. Science 268:403.
43. 3. J. Clin. Invest. 82:640.
44. Winchester, R. J., and G. D. Ross. 1986. Methods for enumerating cell populations by surface markers using conventional microscopy. In Manual of Clinical Laboratory Immunology. N. R. Rose, H. Friedman, and J. L. Fahey, eds. American Society for Microbiology, Washington, D.C., p. 212.
45. Fraker, P. J., and J. C. Speck. 1978. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril. Biochem. Biophys. Res. Commun. 80:849.
46. Williams, D. L., R. B. McNamee, E. L. Jones, H. A. Pretus, H. E. Ensley, I. W. Browder, and N. R. Di Luzio. 1991. A method for the solubilization of a (1→3)-β-D-glucan isolated from Saccharomyces cerevisiae. Carbohydr. Res. 219:203.
47. Cosio, E. G., H. Popperl, W. E. Schmidt, and J. Ebel. 1988. High-affinity binding of fungal β-glucan fragments to soybean (Glycine max L.) microsomal fractions and protoplasts. Eur. J. Biochem. 175:309.
48. Ross, G. D., V. Větvička, and B. P. Thornton. 1998. Analysis of the phagocyte membrane lectin CR3 (CD11b/CD18) using fluorescence-labeled polysaccharides and flow cytometry. In Phagocyte Functions: A Guide for Research and Clinical Evaluation. J. P. Robinson and G. F. Babcock, eds. John Wiley & Sons, New York, p. 1.
49. O'Reilly, D. R., L. K. Miller, and V. A. Luckow. 1992. Baculovirus Expression Vectors. W. H. Freeman and Co., New York.
50. Ross, G. D., and J. D. Lambris. 1982. Identification of a C3bi-specific membrane complement receptor that is expressed on lymphocytes, monocytes, neutrophils, and erythrocytes. J. Exp. Med. 155:96.
51. Lu, C. F., C. Oxvig, and T. A. Springer. 1998. The structure of the β-propeller domain and C-terminal region of the integrin αM subunit: dependence on β subunit association and prediction of domains. J. Biol. Chem. 273:15138.
52. Rabb, H., M. Michishita, C. P. Sharma, D. Brown, and M. A. Arnaout. 1993. Cytoplasmic tails of human complement receptor type 3 (CR3, CD11b/CD18) regulate ligand avidity and the internalization of occupied receptors. J. Immunol. 151:990.
53. Roubey, R. A. S., G. D. Ross, J. T. Merrill, F. Walton, W. Reed, R. J. Winchester, and J. P. Buyon. 1991. Staurosporine inhibits neutrophil phagocytosis but not iC3b binding mediated by CR3 (CD11b/CD18). J. Immunol. 146:3557.
54. Müller, A., P. J. Rice, H. E. Ensley, P. S. Coogan, J. H. Kalbfleisch, J. L. Kelley, E. J. Love, C. A. Portera, T. Z. Ha, I. W. Browder, et al. 1996. Receptor binding and internalization of a water-soluble (1→3)-β-D-glucan biologic response modifier in two monocyte macrophage cell lines. J. Immunol. 156:3418.
55. Hogg, N., R. C. Landis, P. A. Bates, P. Stanley, and A. M. Randi. 1994. The sticking point: how integrins bind to their ligands. Trends Cell Biol. 4:379.
56. 2 integrin CR3 (CD11b/CD18). Proc. Natl. Acad. Sci. USA 91:10680.
57. 2 for a specific and high affinity ligand, NIF. J. Biol. Chem. 272:17558.