Definition and refinement of a region of loss of heterozygosity at 11q23.3-q24.3 in epithelial ovarian cancer associated with poor prognosis

Cancer Research

Volumn 56, Issue 5, 1996, Pages 950-954

  Gabra, Hani ^a   Watson, J E Vivienne ^a   Taylor, Karen J ^a   Mackay, James ^a   Leonard, Robert C F ^a   Steel, C Michael ^b   Porteous, David J ^a   Smyth, John F ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER SURVIVAL; CHROMOSOME 11Q; CHROMOSOME LOSS; FEMALE; GENE LOCUS; HUMAN; HUMAN TISSUE; OVARY CANCER; PRIORITY JOURNAL;

CARCINOMA; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 11; FEMALE; HETEROZYGOTE; HUMANS; OVARIAN NEOPLASMS; SURVIVAL ANALYSIS;

EID: 0030021809     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Foulkes, W. D., Campbell, I G , Stamp, G., and Trowsdale, J. Loss of heterozygosity and amplification on chromosome-11q in human ovarian-cancer. Br. J Cancer, 67 268-273, 1993.
2. Gabra, H., Taylor, L., Cohen, B. B., Lessels, A , Eccles, D M , Leonard, R C. F., Smyth, J. F., and Steel, C M Chromosome 11 allele imbalance and clinicopathological correlates in ovarian tumours. Br. J. Cancer, 72 367-375, 1995
3. Carter, S. L , Negrini, M., Baffa, R , Gillum, D. R., Rosenberg, A. L., Schwartz, G. F., and Croce, C. M Loss of heterozygosity at 11q22-q23 in breast cancer Cancer Res., 54: 6270-6274, 1994.
4. Hampton, G. M., Mannermaa, A., Winquist, R., Alavaikko, M., Blanco, G , Taskinen, P. J , Kiviniemi, H., Newsham, I., Cavenee, W K., and Evans, G. A Loss of heterozygosity in sporadic human breast carcinoma: a common region between 11q22 and 11q23 3. Cancer Res , 54 4586-4589, 1994.
5. Negrini, M , Rasio, D., Hampton, G. M , Sabbioni, S., Rattan, S., Carter, S. L., Rosenberg, A. L , Schwartz, G. F , Shiloh, Y , Cavenee, W K., and Croce, C. M Definition and refinement of chromosome 11 regions of loss of heterozy gosity in breast cancer: identification of a new region at 11q23.3. Cancer Res., 55: 3003-3007, 1995
6. Rasio, D , Negrini, M., Maneneti, G , Draggani, T. A., and Croce, C. M. Loss of heterozygosity at chromosome 11q in lung adenorcarcinoma: identification of three independent regions. Cancer Res., 55: 3988-3991, 1995.
7. Keldysh, P. L., Dragani, T A., Fleischman, E. W , Konstantinova, L. N , Perevoschikov, A G., Pierotti, M. A., Della Porta, G., and Kopnin, B. P 11q deletions in human cotorectal carcinoma: cytogenetics and restriction fragment polymorphism analysis. Genes Chromosomes Cancer, 6: 45-50, 1993.
8. Hampton, G. M., Penny, L. A., Baergen, R. N , Larson, A., Brewer, C., Liao, S., Busby-Earle, R. M. C., Williams, A. W. R., Steel, C. M , Bird, C C., Stanbridge, E. J., and Evans, G. A. Loss of heterozygosity in cervical carcinoma, subchromosomal localisation of a putative tumor-suppressor gene to chromosome 11q22-q24. Proc. Natl. Acad. Sci. USA, 91: 6953-6957, 1994.
9. Tomlinson, I. P. M., Gammack, A. J., Stickland, J E , Mann, G J., MacKie, R. M., Kefford, R. F., and McGee, J. O Loss of heterozygosity in malignant-melanoma at loci on chromosome-11 and chromosome-17 implicated in the pathogenesis of other cancers. Genes Chromosomes & Cancer, 7: 169-172, 1993
10. Herbst, R A., Larson, A., Weiss, J., Cavenee, W K., Hampton, G. M., and Arden, K. C. A defined region of loss of heterozygosity at 11q23 in cutaneous malignant melanoma. Cancer Res., 55: 2494-2496, 1995
11. Winqvist, R , Hampton, G. M., Mannermaa, G. Blanco, G., Alavaikko, M., Kiviniemi, H., Taskinen, P. J , Evans, G. A , Wright, F. A., Newsham, I., and Cavenee, W. K. Loss of heterozygosity for chromosome 11 in primary human breast tumors is associated with poor survival after metastasis Cancer Res., 55: 2660-2664, 1995.
12. Savitsky, K , Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D. A , Smith, S., Uziel, T , Sfez, S., Ashkenazi, M , Pecker, I., Frydman, M., Harnik, R., Patanjali, S. R., Simmons, A., Clines, G A , Sartiel, A., Gatti, R. A., Chessa, L., Sanol, O., Lavin, M. S. Jaspers, N J., Taylor, A. R., Arlett, C. F., Miki, T., Weissman, S. M., Lovett, M , Collins, F. S., and Shiloh, Y. A single ataxia telangiectasia gene with a product similar to PI-3 kinase Science (Washington DC), 268: 1749-1753, 1995
13. Eccles, D., Cranston, G., Steel, C. M., Nakamura, Y., and Leonard, R. C. F Allele losses on chromosome 17 in human epithelial ovarian cancer. Oncogene, 5: 1599-1601, 1990.
14. Cohen, B. B., Wallace, M. R., and Crichton, D. N. A comparison of procedures for analysing microsatellite repeat polymorphisms. Mol Cell Probes, 6: 439-442, 1992
15. James, M. R., Richard, C. W. III, Schott, J-J., Youstry, C., Clark, K., Bell, J., Terwilliger, J. D., Hazan, J., Dubay, C., Vignal, A., Agrapart, M., Imai, T , Nakamura, Y., Polymeropoulos, M., Weissenbach, J., Cox, D R., and Lathrop, G. M. A radiation hybrid map of 506 STS markers spanning human chromosome 11. Nat. Genet, 8. 70-76, 1994.
16. Gudmundsson, J., Bartordottir, R. B., Eiriksdottir, G., Baldursson, T., Arason, A., Egilsson, V., and Ingvarsson, S. Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations. Br. J. Cancer, 72: 696-701, 1995.
17. Gabra, H., Langdon, S. P., Watson, J E. V., Hawkins, R. A., Cohen, B. B., Taylor, L., Mackay, J., Steel, C. M., Leonard, R C. F., and Smyth, J. F Loss of heterozygosity at 11q22 correlates with low progesterone receptor content in epithelial ovarian cancer. Clin. Cancer Res , 1: 945-953, 1995.
18. Van Heyningen, V., and Little, P. F. R. Report of the fourth international workshop on human chromosome 11 mapping 1994. Cytogenet. Cell Genet., 69: 128-158, 1995.