Cutting edge: Requirement of class I signal sequence-derived peptides for HLA-E recognition by a mouse cytotoxic T cell clone

Journal of Immunology

Volumn 162, Issue 10, 1999, Pages 5662-5665

  Martinozzi, Silvia ^a   Pacasova, Rita ^a   Boulouis, Henri Jean ^a   Ulbrecht, Matthias ^b   Weiss, Elisabeth H ^b   Sigaux, François ^a   Pla, Marika ^a  

^a SAINT LOUIS HOSPITAL   (France)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN; HLA ANTIGEN CLASS 1; HLA E ANTIGEN; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; CELL MEDIATED LYMPHOLYSIS; CYTOTOXIC T LYMPHOCYTE; EPSTEIN BARR VIRUS; LYMPHOCYTE CLONE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; CLONE CELLS; CYTOTOXICITY, IMMUNOLOGIC; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; MICE; MICE, TRANSGENIC; OLIGOPEPTIDES; PROTEIN SORTING SIGNALS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0033563278     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Braud, V., E. Y. Jones, and A. McMichael. 1997. The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9. Eur. J. Immunol. 27: 1164.
2. Braud, V. M., D. S. J. Allan, D. Wilson, and A. J. McMichael. 1998. TAP-and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide. Curr. Biol. 8:1.
3. Lee, N., D. R. Goodlett, A. Ishitani, H. Marquardt, and D. E. Geraghty. 1998. HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences. J. Immunol. 160:4951.
4. O'Callaghan, C. A., J. Tormo, B. E. Willkox, V. M. Braud, B. K. Jakobsen, D. I. Stuart, A. J. McMichael, J. I. Bell, and E. Y. Jones. 1998. Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E. Mol. Cell 1:531.
5. Carretero, M., G. Palmieri, M. Llano, V. Tullio, A. Santoni, D. E. Geraghty, and M. Lòpez-Botet. 1998. Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants. Eur. J. Immunol. 28:1280.
6. Braud, V. M., D. S. J. Allan, C. A. O'Callaghan, K. Söderström, A. D'Andrea, G. S. Ogg, S. Lazetic, N. T. Young, J. I. Bell, J. H. Phillips, L. L. Lanier, and A. J. McMichael. 1998. HLA-E binds to natural killer cell receptors CD94/ NKG2A, B and C. Nature 391:795.
7. Borrego, F., M. Ulbrecht, E. H. Weiss, J. E. Coligan, and A. G. Brooks. 1998. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis. J. Exp. Med. 187:813.
8. Lee, N., M. Llano, M. Carretero, A. Ishitani, F. Navarro, M. Lòpez-Botet, and D. E. Geraghty. 1998. HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A. Prof. Natl. Acad. Sci. USA 95:5199.
9. Llano, M., N. Lee, F. Navarro, P. A. Garcia, J. P., E. Geraghty, and M. Lòpez-Botet. 1998. HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer. Eur. J. Immunol. 28:2854.
10. Pacasova, R., S. Martinozzi, H.-J. Boulouis, Y. Szpak, M. Ulbrecht, F. Sigaux, E. H. Weiss, and M. Pla. 1999. Cell surface detection of HLA-E gene products with a specific monoclonal antibody. J. Repr. Immunol. In press.
11. Ulbrecht, M., J. Kellermann, J. P. Johnson, and E. H. Weiss. 1992. Impaired intracellular transport and cell surface expression of nonpolymorphic HLA-E: evidence for inefficient peptide binding. J. Exp. Med. 176:1083.
12. Boulouis, H. J., S. Martinozzi, R. Pacasova, C. Piroird, J. C. Vieville, M. Ulbrecht, E. H. Weiss, F. Sigaux, and M. Pla. 1999. Expression of HLA-E in transgenic mice. Transplant. Proc. In press.
13. Ulbrecht, M., T. Honka, S. Person, J. P. Johnson, and E. H. Weiss. 1992. The HLA-E gene encodes two differentially regulated transcripts and a cell surface protein. J. Immunol. 149:2945.
14. Pacasova, R., S. Martinozzi, H.-J. Boulouis, M. Ulbrecht, J.-C. Vieville, F. Sigaux, E. H. Weiss, and M. Pla. 1999. Cell-surface expression and alloantigenic function of a human nonclassical class I molecule (HLA-E) in transgenic mice. J. Immunol. In press.
15. Rocca, A., L. Degos, and M. Pla. 1991. Analysis of primary HLA-specific cytotoxic T cell response in graft-draining lymph nodes: a transgenic mouse model for in vivo recognition of human MHC antigens. Transplantation 52:1062.
16. Starzinski-Powitz, A., K. Pfizenmaier, M. Rollinghoff, and H. Wagner. 1976. In vivo sensitization of T cells to hapten conjugated syngeneic structures of major histocompatibility complex. I. Effect of in vitro culture upon generation of cytotoxic T lymphocytes. Eur. J. Immunol. 6:799.
17. Geraghty, D. E., M. Stockschleader, A. Ishitani, and J. A. Hansen. 1992. Polymorphism at the HLA-E locus predates most HLA-A and -B polymorphism. Hum. Immunol. 33:174.
18. Aldrich, C. J., A. DeCloux, A. S. Woods, R. J. Cotter, M. J. Soloski, and J. Forman. 1994. Identification of a Tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen. Cell 79:649.
19. + T cells expressing Vβ8 TCR: a role of the Qa-1 molecule. Immunity 2:185.
20. Lowen, L. C., C. J. Aldrich, and J. Forman. 1993. Analysis of T cell receptors specific for recognition of class Ib antigens. J. Immunol. 151:6155.
21. Ulbrecht, M., S. Modrow, R. Srivastava, P. A. Peterson, and E. H. Weiss. 1998. Interaction of HLA-E with peptides and the peptide transporter in vitro: implication for its function in antigen presentation. J. Immunol. 160:4375.