Cell surface detection of HLA-E gene products with a specific monoclonal antibody

Journal of Reproductive Immunology

Volumn 43, Issue 2, 1999, Pages 195-201

  Pacasova, Rita ^a   Martinozzi, Silvia ^a   Boulouis, Henri Jean ^a   Szpak, Yann ^a   Ulbrecht, Matthias ^b   Sigaux, François ^a   Weiss, Elisabeth H ^b   Pla, Marika ^a  

^a INSERM   (France)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Cytometry analysis; HLA E; Spleen

Indexed keywords

BETA 2 MICROGLOBULIN; HLA ANTIGEN; HLA E ANTIGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY V16; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN DETECTION; ARTICLE; CELL SURFACE; FLOW CYTOMETRY; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CELL MEMBRANE; H-2 ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; MICE; MICE, TRANSGENIC;

EID: 0032811458     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0378(99)00033-9     Document Type: Article

References (14)

1. Bjorkman P.J., Saper M.A., Samraoui B., Bennett W.S., Strominger J.L., Wiley D.C. Structure of the human class I histocompatibility antigen, HLA-A2. Nature. 329:1987;506-512.
2. Borrego F., Ulbrecht M., Weiss E.H., Coligan J.E., Brooks A.G. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis. J. Exp. Med. 187:1998;813-818.
3. Braud V.M., Allan D.S.J., O'Callaghan C.A., Söderström K., D'Andrea A., Ogg G.S., Lazetic S., Young N.T., Bell J.I., Phillips J.H., Lanier L.L., McMichael A.J. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature. 391:1998;795-799.
4. Carretero M., Palmieri G., Llano M., Tullio V., Santoni A., Geraghty D.E., Lòpez-Botet M. Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants. Eur. J. Immunol. 28:1998;1280-1291.
5. b. Science. 257:1992;919-927.
6. Le Bouteiller P., Lenfant F. Antigen-presenting function(s) of the non-classical HLA-E, -F and -G class I molecules: the beginning of a story. Res. Immunol. 147:1996;301-313.
7. Lee N., Llano M., Carretero M., Ishitani A., Navarro F., Lòpez-Botet M., Geraghty D.E. HLA-E is a major ligand for the NK inhibitory receptor CD94/NKG2A. Proc. Natl. Acad. Sci. USA. 95:1998;5199-5204.
8. Madden D.R. The three-dimensional structure of peptide-MHC complex. Annu. Rev. Immunol. 13:1995;587-622.
9. Reid S.W., McAdam S., Smith K.J., Klenerman P., O'Callaghan C.A., Harlos K., Jakobsen B.K., McMichael A.J., Bell J.I., Stuart D.I., Jones E.Y. Antagonist HIV-1 gag peptides induce structural changes in HLA B8. J. Exp. Med. 184:1996;2279-2286.
10. Smith K.J., Reid S.W., Stuart D.I., McMichael A.J., Jones E.Y, Bell J.I. An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501. Immunity. 4:1996;203-213.
11. Smith K.J., Reid S.W., Harlos K., McMichael A.J., Stuart D.I., Bell J.I., Jones E.Y. Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53. Immunity. 4:1996;215-228.
12. Ulbrecht M., Kellermann J., Johnson J.P., Weiss E.H. Impaired intracellular transport and cell surface expression of nonpolymorphic HLA-E: evidence for inefficient peptide binding. J. Exp. Med. 176:1992;1083-1090.
13. Ulbrecht M., Modrow S., Srivastava R., Peterson P.A., Weiss E.H. Interaction of HLA-E with peptides and the peptide transporter in vitro: implications for its function in antigen presentation. J. Immunol. 168:1998;4375-4385.
14. b at 2.4 A resolution: implications for antigen-determinant selection. Cell. 76:1994;39-50.