Enhanced immunohistochemical detection of autonomic nerve fibers, cytokines and inducible nitric oxide synthase by light and fluorescent microscopy in rat spleen

Journal of Histochemistry and Cytochemistry

Volumn 45, Issue 4, 1997, Pages 599-610

  Meltzer, Jon C ^a   Grimm, Paul C ^a   Greenberg, Arnold H ^b   Nance, Dwight M ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

alkaline phosphatase; c fos; dopamine hydroxylase; IFN ; immunohistochemistry; macrophage; neuropeptide Y; proteinase K; TNF ; tyrosine hydroxylase

Indexed keywords

ALKALINE PHOSPHATASE; CYTOKINE; DOPAMINE BETA MONOOXYGENASE; GAMMA INTERFERON; NEUROPEPTIDE Y; NITRIC OXIDE SYNTHASE; PROTEIN C FOS; PROTEINASE K; TUMOR NECROSIS FACTOR ALPHA; TYROSINE 3 MONOOXYGENASE;

ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVE; CONTROLLED STUDY; ENZYME LOCALIZATION; FLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SPLEEN;

ANIMALIA;

EID: 0030938544     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549704500412     Document Type: Article

References (43)

1. Bandaletova T, Brouet I, Bartsch H, Sugimura T, Esumi H, Ohshima H (1993) Immunohistochemical localization of an inducible form of nitric oxide synthase in various organs of rats treated with Propionibacterium acnes and lipopolysaccharides. APMIS 101:330-336
2. Besedovsky HO, Del Rey A, Sorkin E, Da Prada M, Keller HH (1979) Immunoregulation mediated by the sympathetic nervous system. Cell Immunol 48:346-355
3. Brown AR, Fishman M (1990) Tumor necrosis factor alpha analyzed within individual macrophages by combined immunohistochemistry and computer-aided image analysis. Cell Immunol 130:352-363
4. Buttery LDK, Evans TJ, Springall DR, Carpenter A, Cohen J, Polak JM (1994) Immunochemical localization of inducible nitric oxide synthase in endotoxin-treated rats. Lab Invest 71:755-764
5. Chensue SW, Remick DG, Shmyr-Forsch C, Beals TF, Kunkel SL (1988) Immunohistochemical demonstration of cytoplasmic and membrane-associated tumor necrosis factor in murine macrophages. Am J Pathol 133/3:564-572
6. Collart MAD, Vassalli BJ, Vassalli P (1987) Modulations of functional activity in differentiated macrophages are accompanied by early and transient increase or decrease in c-fos gene transcription. J Immunol 139:949-955
7. Cook HT, Bune AJ, Jansen AS, Taylor GM, Loi RK, Cattell V (1994) Cellular localization of inducible nitric oxide synthase in experimental endotoxic shock in the rat. Clin Sci 87:179-186
8. Damoiseaux JGMC, Dopp EA, Calame W, Chao D, MacPherson GG, Dijkstra CD (1994) Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1. Immunology 83:140-147
9. Diamond JR, Pesek I (1991) Glomerular tumor necrosis factor and interleukin 1 during acute aminonucleoside nephrosis. Lab Invest 64:21-28
10. Dureus P, Louis D, Grant AV, Bilfinger TV, Stefano GB (1993) Neuropeptide Y inhibits human and invertebrate immunocyte chemotaxis, chemokinesis, and spontaneous activation. Cell Mol Neurobiol 13:541-546
11. Felten DL, Ackerman KD, Wiegand SJ, Feiten SY (1987a) Noradrenergic sympathetic innervation of the spleen: I. Nerve fibers associated with lymphocytes and macrophages in specific compartments of the splenic white pulp. J Neurosci Res 18:28-36
12. Felten DL, Felten SY, Bellinger DL, Carlson SL, Ackerman KD, Madden KS, Olschowka JA, Livnat S (1987b) Noradrenergic sympathetic neural interaction with the immune system: structure and function. Immunol Rev 100:221-260
13. Fukushima T, Sekizawa K, Jin Y, Yamaya M, Sasaki H, Takishima T (1993) Effects of beta-adrenergic receptor activation on alveolar macrophage cytoplasmic motility. Am J Physiol 265:L67-L72
14. Hamilton JA, Veis N, Bordun A, Vairo G, Gonda TJ, Phillips WA (1989) Activation and proliferation signals in murine macrophage: Relationships among c-fos and c-myc expression, phosphoinositide hydrolysis, superoxide formation, and DNA synthesis. J Cell Physiol 141:618-626
15. Heinzel FP, Rerko RM, Ling P, Hakimi J, Schoenhaut DS (1994) Interleukin-12 is produced in vivo during endotoxemia and stimulates synthesis of gamma interferon. Infect Immun 62:4244-4249
16. Heremans H, Dillen C, van Damme J, Billiau A (1994) Essential role for natural killer cells in the lethal lipopolysaccharide-induced Shwartzman-like reaction in mice. Eur J Immunol 24:1155-1160
17. Hewett JA, Roth RA (1993) Hepatic and extrahepatic pathobiology of bacterial lipopolysaccharides. Pharmacol Rev 45:381-411
18. Hofsli E, Bakke O, Nonstad U, Espevik T (1989) A flow cytometric and immunofluorescence microscopy study of tumor necrosis factor production and localization in human monocytes. Cell Immunol 122:405-415
19. Hu X, Goldmutz EA, Brosnan CF (1991) The effect of norepinephrine on endotoxin-mediated macrophage activation. J Neuroimmunol 31:35-42
20. Hu H, Moller G (1994) Lipopolysaccharide-stimulated events in B cell activation. Scand J Immunol 40: 221-227
21. Introna M, Hamilton TA, Kaufman RE, Adams DO, Bast Jr RC (1986) Treatment of murine peritoneal macrophages with bacterial lipopolysaccharide alters expression of c-fos and c-myc oncogenes. J Immunol 137:2711-2715
22. Kouassi E, Li YS, Boukhris W, Millet I, Revillard J (1988) Opposite effects of the catecholamines dopamine and norepinephrine on murine polyclonal B-cell activation. Immunopharmacology 16:125-137
23. Larison KD, Bremiller K, Wells KS, Clements I, Haugland RP (1995) Use of a new flurogenic phosphatase substrate in immunohistochemical applications. J Histochem Cytochem 43:77-83
24. Li C, Ziesmer SC, Lazcano-Villareal O (1987) Use of azide and hydrogen peroxide as an inhibitor for endogenous peroxidase in the immunoperoxidase method. J Histochem Cytochem 35:1457-1460
25. Madden KS, Moynihan JA, Brenner GJ, Felten SY, Felten DL, Livnat S (1994) Sympathetic nervous system modulation of the immune system. III. Alterations in T and B cell proliferation and differentiation in vitro following chemical sympathectomy. J Neuroimmunol 49:77-87
26. Marietta MA (1993) Nitric oxide synthase structure and mechanism. J Biol Chem 268:12231-12234
27. Monastra G, Secchi EF (1993) B-adrenergic receptors mediated in vivo the adrenaline inhibition of lipopolysaccharide-induced tumor necrosis factor release. Immunol Lett 38:127-130
28. Nance DM, Burns J (1989) Innervation of the spleen in the rat: evidence for absence of afferent innervation. Brain Behav Immun 3:281-290
29. Pelletier G, Guy J, Allen YS, Polak JM (1984) Electron microscope immunocytochemical localization of neuropeptide Y (NPY) in the rat brain. Neuropeptides 4:319-324
30. Polak JM, Van Noorden S (1982) Techniques in Immunocytochemistry. Vol 1. London, New York, Paris, San Diego, San Francisco, Toronto, Sao Paulo, Sydney, Tokyo, Academic Press
31. Romano TA, Felten SY, Felten DL, Olschowka JA (1991) Neuropeptide-Y innervation of the rat spleen: another potential immunomodulatory neuropeptide. Brain Behav Immun 5:116-131
32. Sanders VM, Munson AE (1985) Norepinephrine and the antibody response. Pharmacol Rev 37:229-248
33. Sato K, Miyakawa K, Takeya M, Hattori R, Yui Y, Sunamoto M, Ichimori Y, Ushio Y, Takahashi K (1995) Immunohistochemical expression of inducible nitric oxide synthase (iNOS) in reversible endotoxic shock studied by a novel monoclonal antibody against rat iNOS. J Leukocyte Biol 57:36-44
34. Smith PG, Hoffman TL, Reddy H (1991) Sprouting of aberrant neuropeptide Y-immunoreactive sympathetic nerves into neonatally denervated smooth muscle. Regul Peptides 35:103-113
35. Spengler RN, Allen RM, Remick DG, Stricter RM, Kunkel SL (1990) Stimulation of the alpha-adrenergic receptor augments the production of macrophage-derived tumor necrosis factor. J Immunol 145:1430-1434
36. Straus W (1971) Inhibition of peroxidase by methanol and by methanol-nitroferricyanide for use in immunoperoxidase procedures. J Histochem Cytochem 19:682-688
37. Trudrung P, Furness JB, Messenger JP (1994) Locations and chemistries of sympathetic nerve cells that project to the gastrointestinal tract and spleen. Arch Histol Cytol 57:139-150
38. Van der Meide PH, Dubbeld M, Vijverberg K, Kos T, Schellekens H (1986) The purification and characterization of rat gamma interferon by use of two monoclonal antibodies. J Gen Virol 67:1059-1071
39. Vriend CY, Wan W, Greenberg AH, Nance DM (1993) Cutting the splenic nerve differentially affects catecholamine and neuropeptide levels in the spleen. Soc Neurosci Abstr 388.5
40. Wan W, Janz L, Vriend CY, Sorenson CM, Greenberg AH, Nance DM (1993a) Differential induction of c-fos immunoreactivity in hypothalamus and brain stem nuclei following central and peripheral adminstration of endotoxin. Brain Res Bull 32:581-587
41. Wan W, Vriend CY, Wetmore L, Gartner JG, Greenberg AH, Nance DM (1993b) The effects of stress on splenic immune function are mediated by the splenic nerve. Brain Res Bull 30:101-105
42. Wan W, Wetmore L, Sorensen CM, Greenberg AH, Nance DM (1994) Neural and biochemical mediators of endotoxin and stress-induced c-fos expression in the rat brain. Brain Res Bull 34:7-14
43. Zalcman S, Green-Johnson JM, Murray L, Wan W, Nance DM, Greenberg AH (1994) Interleukin-2-induced enhancement of an antigen-specific IgM plaque-forming cell response is mediated by the sympathetic nervous system. J Pharmacol Exp Ther 271:977-982