De novo design of a model peptide sequence to examine the effects of single amino acid substitutions in the hydrophobic core on both stability and oligomerization state of coiled-coils

Journal of Molecular Biology

Volumn 285, Issue 2, 1999, Pages 785-803

  Wagschal, Kurt ^a   Tripet, Brian ^a   Hodges, Robert S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Coiled coil; Hydrophobic core; Oligomerization state; Protein design; Protein stability

Indexed keywords

LEUCINE; PEPTIDE; VALINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; GEL PERMEATION CHROMATOGRAPHY; HYDROPHOBICITY; MODEL; MOLECULAR STABILITY; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DENATURATION; SEDIMENTATION RATE;

EID: 0033556283     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2284     Document Type: Article

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