Preconditioning of bovine endothelial cells: The protective effect is mediated by an adenosine A2 receptor through a protein kinase C signaling pathway

Circulation Research

Volumn 78, Issue 1, 1996, Pages 73-81

  Zhou, Xiaobo ^a   Zhai, Xiaolin ^a   Ashraf, Muhammad ^a,b  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

endothelial cells; preconditioning; protein kinase C

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 8 (4 SULFOPHENYL)THEOPHYLLINE; ADENOSINE A2 RECEPTOR; ADENOSINE DERIVATIVE; ADENOSINE RECEPTOR AFFECTING AGENT; ADENOSINE RECEPTOR BLOCKING AGENT; CALPHOSTIN C; LACTATE DEHYDROGENASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CATTLE; CELL HYPOXIA; CELL PROTECTION; CORONARY ARTERY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART MUSCLE REPERFUSION; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

EID: 0030023207     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.78.1.73     Document Type: Article

References (37)

1. 1 selective agonists offer minimal protection against ischemic injury to isolated rat cardiomyocytes. Cardiovasc Res. 1993;27:1670-1676.
2. DeFily DV, Chilian WM. Preconditioning protects coronary arteriolar endothelium from ischemia-reperfusion injury. Am J Physiol. 1993;265:H700-H706.
3. Richard V, Kaeffer N, Tron C, Thuillez C. Ischemic preconditioning protects against coronary endothelial dysfunction induced by ischemia and reperfusion. Circulation. 1994;89:1254-1261.
4. Bauer B, Simkhovich BZ, Kloner RA, Przyklenk K. Does preconditioning protect the coronary vasculature from subsequent ischemia/reperfusion injury? Circulation. 1993;88:659-672.
5. Belardinelli L, Linden J, Berne RM. The cardiac actions of adenosine. Prog Cardiovasc Dis. 1989;32:73-97.
6. Olsson RA, Pearson JD. Cardiovascular purinoceptors. Physiol Rev. 1990;70:761-845.
7. 2 receptor on human neutrophils. J Immunol. 1985;135:1366-1371.
8. 1-Adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C. Circ Res. 1994;75:576-585.
9. 1-Adrenoceptor activation increases ecto-5′-nucleotidase activity and adenosine release in rat cardiomyocytes by activating protein kinase C. Circulation. 1995;91: 2226-2234.
10. Armstrong S, Downey JM, Ganote CE. Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor. Cardiovasc Res. 1994;28:72-77.
11. Khalid MA, Ashraf M. Maximal · OH production is seen upon reoxygenation of viable anoxic cultured cardiomyocytes but not of compromised cells. Am J Cardiovasc Pathol. 1992;4:245-255.
12. Kaminski PM, Proctor KG. Extracellular and intracellular actions of adenosine and related compounds in the reperfused rat intestine. Circ Res. 1992;71:720-731.
13. 2+ paradox injury in rat heart: role of adenosine. Circ Res. 1994;74:360-367.
14. Bramson HN, Thomas N, DeGrado WF, Kraiser ET. Development of a convenient spectrophotometric assay for peptide phosphorylation catalyzed by adenosine 3′,5′-monophosphate dependent protein kinase. J Am Chem Soc. 1980;102:7156-7157.
15. Marala RB, Ways K, Mustafa SJ. 2-Chloroadenosine prevents phorbol ester-induced depletion of protein kinase C in porcine coronary artery. Am J Physiol. 1993;264:H1465-H1471.
16. Wallenstein S, Zuker CL, Fleiss JL. Some statistical methods useful in circulation research. Circ Res. 1980;47:1-9.
17. Zhai XL, Lawson CS, Cave AG, Hearse DJ. Preconditioning and post-ischemic contractile dysfunction: the role of impaired oxygen delivery vs extracellular metabolite accumulation. J Mol Cell Cardiol. 1993;25:847-857.
18. Vanhoutte PM, Rubanyi GM, Miller VM, Houston DS. Modulation of vascular smooth muscle contraction by the endothelium. Annu Rev Physiol. 1986;48:307-320.
19. Curry F-RE, Joyner WL. Modulation of capillary permeability: method and measurement in individually perfused mammalian frog microvessels. In: Ryan US, ed. Endothelium. Boca Raton, Fla: CRC Press; 1988;1:3-17.
20. Azuma H, Ishikawa M, Sekizaki S. Endothelium dependent inhibition of platelet aggregation. Br J Pharmacol. 1988;88:411-415.
21. Harker LA. Endothelium and hemostasis. In: Ryan US, ed. Endothelium. Boca Raton, Fla: CRC Press; 1988;1:167-177.
22. 2 receptors in cultured coronary endothelial cells. Naunyn Schmiedebergs Arch Pharmacol. 1987;336:94-98.
23. 2-receptor agonists on myocardial reperfusion injury. Am Heart J. 1992;123:332-338.
24. 1 receptor mediated protection of the globally ischemic isolated rat heart. J Mol Cell Cardiol. 1990;22:39-47.
25. Ytrehus K, Liu Y, Downey JM. Preconditioning protects ischemic rabbit heart by protein kinase C activation. Am J Physiol. 1994;266: H1145-H1152.
26. - currents in feline ventricular myocytes. Circ Res. 1994;75:133-143.
27. Abebe W, Makujina S, Mustafa SJ. Adenosine receptor-mediated relaxation of porcine coronary artery in presence and absence of endothelium. Am J Physiol. 1994;266:H2018-H2025.
28. 1-Receptor - independent activation of protein kinase C in acute myocardial ischemia: mechanisms for sensitization of the adenylyl cyclase system. Circ Res. 1992;70:1304-1312.
29. Yuan S, Sunahara FA, Sen AK. Tumor-promoting phorbol esters inhibit cardiac functions and induce redistribution of protein kinase C in perfused beating rat heart. Circ Res. 1987;61:372-378.
30. Thornton JD, Liu GS, Downey JM. Pretreatment with pertussis toxin blocks the protective effects of preconditioning: evidence for a G-protein mechanism. J Mol Cell Cardiol. 1993;25:311-320.
31. Kohl C, Linck B, Schmitz W, Scholz H, Scholz J, Toth M. Effects of carbachol and (-)-N6-phenylisopropyladenosine on myocardial inositol phosphate content and force of contraction. Br J Pharmacol. 1990;101:829-834.
32. Singer HA. Phorbol ester-induced stress and myosin light chain phosphorylation in swine carotid medial smooth muscle. J Pharmacol Exp Ther. 1990;252:1068-1074.
33. Zhou XB, Zhai XL, Ashraf M. Preconditioning of bovine coronary endothelial cells is mediated by a protein kinase C signaling pathway. Circulation. 1994;90(suppl I):I-371. Abstract.
34. Brooks G, Walsh R, Downey J. Phosphorylation of 80K/MARCKS, a specific substrate of protein kinase C, occurs after 5′ ischemia but only in preconditioned hearts. Circulation. 1993;88(suppl I):I-101. Abstract.
35. ATP channels. Circulation. 1994;89:1229-1236.
36. Maulik N, Engelman RM, Wei ZJ, Lu D, Rousou JA, Das DK. Interleukin-1α preconditioning reduces myocardial ischemia reperfusion injury. Circulation. 1993;88(suppl II):II-387-II-394.
37. Marber MS, Latchman DS, Walker JM, Yellon DM. Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction. Circulation. 1993;88:1264-1272.