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Volumn 121, Issue 14, 1999, Pages 3249-3255

Synthesis and thermodynamic and biophysical properties of tricyclo-DNA

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DOUBLE STRANDED DNA; NUCLEOSIDE ANALOG; PHOSPHODIESTERASE;

EID: 0033553176     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja983570w     Document Type: Article
Times cited : (112)

References (43)
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    • (b) Nguyen Thuong, T.; Hélène, C. Angew. Chem. 1993, 105, 697-723; Angew. Chem., Int. Ed. Engl. 1993, 33, 666.
    • (1993) Angew. Chem., Int. Ed. Engl. , vol.33 , pp. 666
  • 8
  • 16
    • 84918313906 scopus 로고
    • Unsubstituted 1-hydroxybicyclo[n.1.0]cycloalkanes (n = 3-6) react in contrast to the here described tricyclonucleosides under similar conditions to α-methylcycloalkanones and not to ring enlarged products (see: Conia, J. M. Pure Appl. Chem. 1975, 43, 317-326). As ring-opening reactions of cyclopropanols are sensitive to the location and orientation of the substituents (see: Reusch, W.; Grimm, K.; Karoglan, J.; Martin, J.; Subrahamanian, K.; Venkataramani, P. S.; Yordy, J. J. Am. Chem. Soc. 1977, 99, 1958-1964), the different reactivity might be connected with the substitution pattern at the carbocyclic five-membered ring of the tricyclonucleosides.
    • (1975) Pure Appl. Chem. , vol.43 , pp. 317-326
    • Conia, J.M.1
  • 17
    • 0039668428 scopus 로고
    • Unsubstituted 1-hydroxybicyclo[n.1.0]cycloalkanes (n = 3-6) react in contrast to the here described tricyclonucleosides under similar conditions to α-methylcycloalkanones and not to ring enlarged products (see: Conia, J. M. Pure Appl. Chem. 1975, 43, 317-326). As ring-opening reactions of cyclopropanols are sensitive to the location and orientation of the substituents (see: Reusch, W.; Grimm, K.; Karoglan, J.; Martin, J.; Subrahamanian, K.; Venkataramani, P. S.; Yordy, J. J. Am. Chem. Soc. 1977, 99, 1958-1964), the different reactivity might be connected with the substitution pattern at the carbocyclic five-membered ring of the tricyclonucleosides.
    • (1977) J. Am. Chem. Soc. , vol.99 , pp. 1958-1964
    • Reusch, W.1    Grimm, K.2    Karoglan, J.3    Martin, J.4    Subrahamanian, K.5    Venkataramani, P.S.6    Yordy, J.7
  • 19
    • 2442757601 scopus 로고    scopus 로고
    • Dissertation, Universität Bern, in preparation
    • Steffens, R. Dissertation, Universität Bern, in preparation.
    • Steffens, R.1
  • 25
    • 0029949701 scopus 로고    scopus 로고
    • (a) McKay, D. RNA 1996, 2, 395-403.
    • (1996) RNA , vol.2 , pp. 395-403
    • McKay, D.1
  • 29
    • 0001120760 scopus 로고    scopus 로고
    • Kool, E. T. Chem. Rev. 1997, 97, 1473-1487.
    • (1997) Chem. Rev. , vol.97 , pp. 1473-1487
    • Kool, E.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.