A longitudinal study of cerebral glucose metabolism, MRI, and disability in patients with MS

Neurology

Volumn 53, Issue 1, 1999, Pages 149-153

  Blinkenberg, Morten ^a   Jensen, C V ^b   Holm, S ^a   Paulson, O B ^a,b   Sorensen P S ^a  

^a International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^b HVIDOVRE HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN METABOLISM; CLINICAL ARTICLE; DISABILITY; DISEASE COURSE; DISEASE SEVERITY; FEMALE; FRONTAL CORTEX; GLUCOSE METABOLISM; HUMAN; LONGITUDINAL STUDY; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PARIETAL LOBE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

EID: 0033551541     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.53.1.149     Document Type: Article

References (35)

1. Paty DW, Li DK. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. UBC MS/MRI Study Group and the IFNβ Multiple Sclerosis Study Group. Neurology 1993;43:662-667.
2. Rao SM, Leo GJ, Haughton VM, et al. Correlation of magnetic resonance imaging with neuropsychological testing in multiple sclerosis. Neurology 1989;39:161-166.
3. Swirsky Sacchetti T, Mitchell DR, Seward J, et al. Neuropsychological and structural brain lesions in multiple sclerosis: a regional analysis. Neurology 1992;42:1291-1295.
4. Franklin GM, Heaton RK, Nelson LM, et al. Correlation of neuropsychological and MRI findings in chronic/progressive multiple sclerosis. Neurology 1988;38:1826-1829.
5. Losseff NA, Wang L, Lai HM, et al. Progressive cerebral atrophy in multiple sclerosis. A serial MRI study. Brain 1996;119: 2009-2019.
6. Kidd D, Thorpe JW, Thompson AJ, et al. Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis. Neurology 1993;43:2632-2637.
7. Gass A, Barker GJ, Kidd D, et al. Correlation of magnetization transfer ratio with clinical disability in multiple sclerosis. Ann Neurol 1994;36:62-67.
8. 18F-FDG PET study. Neuroimage 1996;4:87-96.
9. Brooks DJ, Leenders KL, Head G, et al. Studies on regional cerebral oxygen utilisation and cognitive function in multiple sclerosis. J Neurol Neurosurg Psychiatry 1984;47:1182-1191.
10. Pozzilli C, Passafiume D, Bernardi S, et al. SPECT, MRI and cognitive functions in multiple sclerosis. J Neurol Neurosurg Psychiatry 1991;54:110-115.
11. Lycke J, Wikkelso C, Bergh AC, et al. Regional cerebral blood flow in multiple sclerosis measured by single photon emission tomography with technetium-99m hexamethylpropyleneamine oxime. Eur Neurol 1993;33:163-167.
12. 18F-fluorodeoxyglucose positron emission tomography study. Neurology 1997;48: 1566-1571.
13. Sun X, Tanaka M, Kondo S, et al. Clinical significance of reduced cerebral metabolism in multiple sclerosis: a combined PET and MRI study. Ann Nucl Med 1998;12:89-94.
14. Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227-231.
15. Rota Kops E, Herzog H, Schmid A, et al. Performance characteristics of an eight-ring whole body PET scanner. J Comput Assist Tomogr 1990;14:437-445.
16. Sokoloff L, Reivich M, Kennedy C, et al. The 14-C-deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 1977; 28:897-916.
17. Huang S, Phelps ME, Hoffman EJ, et al. Noninvasive determination of local cerebral metabolic rate of glucose in man. Am J Physiol 1980;238:E69-E82.
18. Hasselbalch SG, Madsen PL, Knudsen GM, et al. Calculation of the FDG lumped constant by simultaneous measurements of global glucose and FDG metabolism in humans. J Cereb Blood Flow Metab 1998;18:154-160.
19. 11C]deoxyglucose. J Cereb Blood Flow Metab 1985;5: 179-192.
20. Brownell B, Hughes JT. The distribution of plaques in the cerebrum in multiple sclerosis. J Neurol Neurosurg Psychiatry 1962;25:315-320.
21. Greitz T, Bohm C, Holte S, et al. A computerized brain atlas: construction, anatomical content, and some applications. J Comput Assist Tomogr 1991;15:26-38.
22. Woods RP, Cherry SR, Mazziotta JC. Rapid automated algorithm for aligning and reslicing PET images. J Comput Assist Tomogr 1992;16:620-633.
23. Plummer DL. DispImage: a display and analysis tool for medical images. Riv Neuroradiol 1992;5:489-495.
24. Matthews JN, Altman DG, Campbell MJ, et al. Analysis of serial measurements in medical research. BMJ 1990;300: 230-235.
25. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an Expanded Disability Status Scale (EDSS). Neurology 1983;33:1444-1452.
26. Bartlett EJ, Brodie JD, Wolf AP, et al. Reproducibility of cerebral glucose metabolic measurements in resting human subjects. J Cereb Blood Flow Metab 1988;8:502-512.
27. Tyler JL, Strother SC, Zatorre RJ, et al. Stability of regional cerebral glucose metabolism in the normal brain measured by positron emission tomography. J Nucl Med 1988;29:631-642.
28. 18F]-2-fluoro-2-deoxy-D-glucose method in resting, healthy human subjects. Eur J Nucl Med 1990;16:267-273.
29. Moeller JR, Ishikawa T, Dhawan V, et al. The metabolic topography of normal aging. J Cereb Blood Flow Metab 1996;16: 385-398.
30. Loessner A, Alavi A, Lewandrowski KU, et al. Regional cerebral function determined by FDG-PET in healthy volunteers: normal patterns and changes with age. J Nucl Med 1995;36: 1141-1149.
31. Willoughby EW, Grochowski E, Li DK, et al. Serial magnetic resonance scanning in multiple sclerosis: a second prospective study in relapsing patients. Ann Neurol 1989;25:43-49.
32. Mammi S, Filippi M, Martinelli V, et al. Correlation between brain MRI lesion volume and disability in patients with multiple sclerosis. Acta Neurol Scand 1996;94:93-96.
33. Trapp BD, Peterson J, Ransohoff RM, et al. Axonal transection in the lesions of multiple sclerosis. N Engl J Med 1998; 338:278-285.
34. Weinshenker BG, Bass B, Rice GP, et al. The natural history of multiple sclerosis: a geographically based study. I. Clinical course and disability. Brain 1989;112:133-146.
35. Roelcke U, Curt A, Otte A, et al. Influence of spinal cord injury on cerebral sensorimotor systems: a PET study. J Neurol Neurosurg Psychiatry 1997;62:61-65.