Altered product pattern of a squalene-hopene cyclase by mutagenesis of active site residues

Tetrahedron Letters

Volumn 40, Issue 11, 1999, Pages 2121-2124

  Merkofer, Thorsten ^a   Pale Grosdemange, Catherine ^b   Wendt, Karl Ulrich ^c   Rohmer, Michel ^b   Poralla, Karl ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Hopene; Squalene cyclization; Triterpene synthase

Indexed keywords

BACTERIAL ENZYME; LANOSTEROL SYNTHASE;

AMINO ACID SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; GENE MUTATION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ALICYCLOBACILLUS ACIDOCALDARIUS; BACTERIA (MICROORGANISMS);

EID: 0033548668     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00145-8     Document Type: Article

References (8)

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