PHR1 encodes an abundant, pleckstrin homology domain-containing integral membrane protein in the photoreceptor outer segments

Journal of Biological Chemistry

Volumn 274, Issue 50, 1999, Pages 35676-35685

  Xu, Shunbin ^a   Ladak, Rahim ^b   Swanson, Deborah A ^a   Soltyk, Anna ^b   Sun, Hui ^a   Ploder, Lynda ^a   Vidgen, Danka ^b   Duncan, Alessandra M V ^c   Garami, Elizabeth ^b   Valle, David ^a,d   McInnes, Roderick R ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c MONTREAL CHILDREN S HOSPITAL   (Canada)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GLUTATHIONE TRANSFERASE; MEMBRANE PROTEIN; PLECKSTRIN; TRANSDUCIN;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BRAIN; CELLULAR DISTRIBUTION; EXON; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTRON; MOLECULAR CLONING; MOUSE; NONHUMAN; PHOTORECEPTOR; PHOTOTRANSDUCTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN LOCALIZATION; RETINA; RETINA GANGLION CELL; SEQUENCE HOMOLOGY;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; APOENZYMES; BASE SEQUENCE; BLOTTING, NORTHERN; BRAIN; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 11; DEOXYRIBODIPYRIMIDINE PHOTO-LYASE; EXONS; FUNGAL PROTEINS; GENES; HUMANS; INTRONS; MEMBRANE GLYCOPROTEINS; MICE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PROMOTER REGIONS (GENETICS); RETINA; ROD OUTER SEGMENTS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SRC HOMOLOGY DOMAINS; TRANSCRIPTION, GENETIC;

EID: 0033544927     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.50.35676     Document Type: Article

References (90)

1. Dryja, T. P., McGee, T. L., Reichel, E., Hahn, L. B., Cowley, G. S., Yandell, D. W., Sandberg, M. A., and Berson, E. L. (1990) Nature 343, 364-366
2. Nathans, J., and Hogness, D. S. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 8451-4885
3. Kubo, M., Hirano, T., and Kakinuma, M. (1991) FEBS Lett. 291, 245-248
4. Van Dop, C., Medynski, D. C., and Apone, L. M. (1989) Nucleic Acids Res. 17, 4887
5. Pittler, S. J., Baehr, W., Wasmuth, J. J., McConnell, D. G., Champagne, M. S., van Tuinen, P., Ledbetter, D., and Davis, R. L. (1990) Genomics 6, 272-283
6. Khramtsov, N. V., Feshchenko, E. A., Suslova, V. A., Shmukler, B. E., Terpugov, B. E., Rakitina, T. V., Atabekova, N. V., and Lipkin, V. M. (1993) FEBS Lett. 327, 275-278
7. McLaughlin, M. E., Sandberg, M. A., Berson, E. L., and Dryja, T. P. (1993) Nat. Genet. 4, 130-134
8. Huang, S. H., Pittler, S. J., Huang, X., Oliveira, L., Berson, E. L., and Dryja, T. P. (1995) Nat. Genet. 11, 468-471
9. Bascom, R. A., Schappert, K., and McInnes, R. R. (1993) Hum. Mol. Genet. 2, 385-391
10. Travis, G. H., Christerson, L., Danielson, P. E., Klisak, I., Sparkes, R. S., Hahn, L. B., Dryja, T. P., and Sutcliffe, J. G. (1991) Genomics 10, 733-739
11. Kajiwara, K., Hahn, L. B., Mukai, S., Travis, G. H., Berson, E. L., and Dryja, T. P. (1991) Nature 354, 480-483
12. Kajiwara, K., Berson, E. L., and Dryja, T. P. (1994) Science 264, 1604-1608
13. Illing, M., Molday, L. L., and Molday, R. S. (1997) J. Biol. Chem. 272, 10303-10310
14. Allikmets, R. (1997) Nat. Genet. 17, 122
15. Sun, H., and Nathans, J. (1997) Nat. Genet. 17, 15-16
16. Freund, C. L., Wang, Q.-L., Chen, S., Muskat, B. L., Wiles, C. D., Sheffield, V. C., Jacobson, S. G., McInnes, R. R., Zack, L. J., and Stone, E. M. (1998) Nat. Genet. 18, 311-312
17. Chen, S., Wang, Q. L., Nie, Z., Sun, H., Lennon, G., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., and Zack, D. J. (1997) Neuron 19, 1017-1030
18. Furukawa, T., Morrow, E. M., and Cepko, C. L. (1997) Cell 91, 531-541
19. Gregory-Evans, K., and Bhattacharya, S. S. (1998) Trends Genet. 14, 103-108
20. Dryja, T. R., and Li, T. (1995) Hum. Mol. Genet. 4, 1739-1743
21. Swanson, D. A., Freund, C. L., Steel, J. M., Xu, S., Ploder, L., McInnes, R. R., and Valle, D. (1997) Genome Res. 7, 513-521
22. Krappa, R., Nguyen, A., Burrola, P., Deretic, D., and Lemke, G. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 4633-4638
23. Tyers, M., Rachubinski, R. A., Stewart, M. I., Varrichio, A. M., Shorr, R. G., Haslam, R. J., and Harley, C. B. (1988) Nature 333, 470-473
24. Mayer, B. J., Ren, R., Clark, K. L., and Baltimore, D. (1993) Cell 73, 629-630
25. Haslam, R. J., Koide, H. B., and Hemmings, B. A. (1993) Nature 363, 309-310
26. Musacchio, A., Gibson, T., Rice, P., Thompson, J., and Saraste, M. (1993) Trends Biochem. Sci. 18, 343-348
27. Ingley, E., and Hemmings, B. A. (1994) J. Cell. Biochem. 56, 436-443
28. Shaw, G. (1996) BioEssays 18, 35-46
29. Lemmon, M. A., Ferguson, K. M., and Schlessinger, J. (1996) Cell 86, 621-624
30. Harlan, J. E., Hajduk, P. J., Yoon, H. S., and Fesik, S. W. (1994) Nature 371, 168-
31. Toker, A., and Cantley, L. C. (1997) Nature 387, 673-676
32. Fukuda, M., Kojima, T., Kabayama, H., and Mikoshiba, K. (1996) J. Biol. Chem. 271, 30303-30306
33. Rameh, L. E., Arvidsson, A.-K., Carraway, K. L., III, Couvillon, A. D., Rathbun, G., Crompton, A., VanRenterghem, B., Czech, M. P., Ravichandran, K. S., Burakoff, S. J., Wang, D.-S., Chen, C.-S., and Cantley, L. C. (1997) J. Biol. Chem. 272, 22059-22066
34. Jiang, Y., Ma, W., Wan, Y., Kozasa, T., Hattori, S., and Huang, X.-Y. (1998) Nature 395, 808-810
35. Bence, K., Ma, W., Kozasa, T., and Huang, X.-Y. (1997) Nature 389, 296-300
36. Tsukada, S., Simon, M. I., Witte, O. N., and Katz, A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 11256-11260
37. Mahadevan, D., Thanki, N., Singh, J., McPhie, P., Zangrilli, D., Wang, L.-M., Guerrero, C., LeVine, H., Humblet, C., Saldanha, J., Gutkind, J. S., and Najmabadi-Haske, T. (1995) Biochemistry 34, 9111-9117
38. Langhans-Rajasekaran, S., Wan, Y., and Huang, X.-Y. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8601-8605
39. Koch, W. J., Inglese, J., Stone, W. C., and Lefkowitz, R. J. (1993) J. Biol. Chem. 268, 8256-8260
40. Srinivasan, N., Waterfield, M. D., and Blundell, T. L. (1996) Biochem. Biophys. Res. Commun. 220, 697-702
41. Haske, T. N., DeBlasi, A., and LeVine, H., III (1996) J. Biol. Chem. 271, 2941-2948
42. Touhara, K., Inglese, J., Pitcher, J. A., Shaw, G., and Lefkowitz, R. J. (1994) J. Biol. Chem. 271, 2941-2948
43. Peng, Y. W., Rhee, S. G., Yu, W. P., Ho, Y. K., Schoen, T., Chader, G. J., and Yau, K. W. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 1995-2000
44. Schaeren-Wiemers, N., and Gerfin-Moser, A. (1993) Histochemistry 100, 431-440
45. Smith, D. E., and Fisher, P. A. (1984) J. Cell Biol. 99, 20-28
46. Papermaster, D. S. (1982) Methods Enzymol. 81, 48-52
47. Kühn, H. (1982) Methods Enzymol. 81, 556-575
48. Crane, D. I., Kalish, J. E., and Gould, S. J. (1994) J. Biol. Chem. 269, 21835-21844
49. Watson, A. J., Aragay, A. M., Slepak, V. Z., and Simon, M. I. (1996) J. Biol. Chem. 271, 28154-28160
50. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, G. J., Smith, J. A., and Struhl, K. (1991) Current Protocols in Molecular Biology, John Wiley & Sons, New York
51. Kozak, M. (1983) Microbiol. Rev. 47, 1-45
52. Bellacosa, A., Testa, J. R., Staal, S. P., and Tsichlis, P. N. (1991) Science 254, 274-277
53. Coffer, P. J., and Woodgett, J. R. (1991) Eur. J. Biochem. 201, 475-481
54. Jones, P. F., Jakubowicz, T., Pitossi, F. J., Maurer, F., and Hemminga, B. A. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 4171-4175
55. Dawson, P. A., Ridgway, N. D., Slaughter, C. A., Brown, M. S., and Goldstein, J. L. (1989) J. Biol. Chem. 284, 16798-16803
56. Levine, T. P., and Munro, S. (1998) Curr. Biol. 8, 729-739
57. Liu, L., and Pohajdak, B. (1992) Biochim. Biophys. Acta 1132, 75-78
58. Meacci, E., Tsai, S.-C., Adamik, R., Moss, J., and Vaughan, M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 1745-1748
59. Chardin, P., Paris, S., Antonny, B., Robineau, S., Beraud-Dufour, S., Jackson, C. L., and Chabre, M. (1996) Nature 384, 481-484
60. Diatloff-Zito, C., Gordon, A. J., Duchaud, E., and Merlin, G. (1995) Gene (Amst.) 163, 301-306
61. Kasai, K., Shin, H.-W., Shinotsuka, C., Murakami, K., and Nakayama, K. (1999) J. Biochem. (Tokyo) 125, 780-789
62. Klein, D. E., Lee, A., Frank, D. W., Marks, M. S., and Lemmon, M. A. (1998) J. Biol. Chem. 273, 27725-27733
63. van der Bliek, A. M., Redelmeier, T. E., Damke, H., Tisdale, E. J., Meyerowitz, E. M., and Schmid, S. L. (1993) J. Cell Biol. 122, 553-563
64. Lolley, R. N., Craft, C. M., and Lee, R. H. (1992) Neurochem. Res. 17, 81-89
65. Blackshaw, S., and Snyder, S. H. (1997) J. Neurosci. 17, 8074-8082
66. Kutay, U., Hartmann, E., and Rapoport, T. A. (1993) Trends Cell Biol. 3, 72-75
67. Pierce, M. E., Sheshberadaran, H., Zhang, Z., Fox, L. E., Applebury, M. L., and Takahashi, J. S. (1993) Neuron 10, 579-584
68. Lee, R. H., Brown, B. M., and Lolley, R. N. (1984) Biochemistry 23, 1972-1977
69. Abe, T., Nakabayashi, H., Tamada, H., Takagi, T., Sakuragi, S., Yamaki, K., and Shinohara, T. (1990) Gene (Amst.) 91, 209-215
70. Watanabe, Y., Kawasaki, K., Miki, N., and Kuo, C.-H. (1990) Biochem. Biophys. Res. Commun. 170, 951-956
71. Lee, R. H., Lieberman, B. S., and Lolley, R. N. (1987) Biochemistry 26, 3983-3990
72. Danner, S., and Lohse, M. J. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 10145-10150
73. Yoshida, T., Willardson, B. M., Wilkins, J. F., Jensen, G. J., Thornton, B. D., and Bitensky, M. W. (1994) J. Biol. Chem. 269, 24050-24057
74. Wilkins, J. F., Bitensky, M. W., and Willardson, B. M. (1996) J. Biol. Chem. 271, 19232-19237
75. Lee, R. H., Ting, T. D., Lieberman, B. S., Tobias, D. E., Lolley, R. N., and Ho, Y.-K. (1992) J. Biol. Chem. 267, 25104-25112
76. Bauer, P. H., Müller, S., Puzicha, M., Pippig, S., Obermaier, B., Helmreich, E. J. M., and Lohse, M. J. (1992) Nature 358, 73-76
77. Bauer, P. H., Blüml, K., Schröder, S., Hegler, J., Dees, C., and Lohse, M. J. (1998) J. Biol. Chem. 273, 9465-9471
78. Watson, A. J., Katz, A., and Simon, M. I. (1994) J. Biol. Chem. 269, 22150-22156
79. He, W., Cowan, C. W., and Wensel, T. G. (1998) Neuron 20, 95-102
80. Makino, E. R., Handy, J. W., Li, T., and Arshavsky, V. Y. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1947-1952
81. Franke, T. F., Kaplan, D. R., Cantley, L. C., and Toker, A. (1997) Science 275, 665-668
82. Klippel, A., Kavanaugh, W. M., Pot, D., and Williams, L. T. (1997) Mol. Cell. Biol. 17, 338-344
83. Konishi, H., Kuroda, S., Tanaka, M., Matsuzaki, H., Ono, Y., Kameyama, K., Haga, T., and Kikkawa, U. (1995) Biochem. Biophys. Res. Commun. 216, 526-534
84. Tanaka, M., Konishi, H., Touhara, K., Sakane, F., Hirata, M., Ono, Y., and Kikkawa, U. (1999) Biochem. Biophys. Res. Commun. 255, 169-174
85. Klarlund, J. K., Guilherme, A., Holik, J. J., Virbasius, J. V., Chawla, A., and Czech, M. P. (1997) Science 275, 1927-1930
86. Salim, K., Bottomley, M. J., Querfurth, E., Zvelebil, M. J., Gout, I., Scaife, R., Margolis, R. L., Gigg, R., Smith, C. I. E., Driscoll, P. C., Waterfield, M. D., and Panayotou, G. (1996) EMBO J. 15, 6241-6250
87. Bottomley, M. J., Surdo, P. L., and Driscoll, P. C. (1999) Curr. Biol. 9, R301-R304
88. de Juan, E. J. (1994) in Retina (Glaser, B. M., ed) pp. 2499-2521, Mosby, Baltimore
89. Weil, D., Blanchard, S., Kaplan, J., Guilford, P., Gibson, F., Walsh, J., Mburu, P., Varela, A., Levilliers, J., Weston, M. D., Kelley, P. M., Kimberling, W. J., Wagenaar, M., Levi-Acobas, F., Larget-Plet, D., Munnich, A., Steel, K. P., Brown, S. D. M., and Petit, C. (1995) Nature 374, 60-61
90. Soucy, E., Wang, Y., Nirenberg, S., Nathans, J., and Meister, M. (1998) Neuron 21, 481-493