Quinuclidine N-oxide: A potential replacement for HMPA

Chemical Communications

Volumn , Issue 1, 1999, Pages 59-60

  O'Neil, Ian A ^a   Lai, Justine Y Q ^b   Wynn, Duncan ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDE; HEMPA; QUINUCLIDINE DERIVATIVE;

ARTICLE; CHEMICAL REACTION;

EID: 0033531223     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/a808779b     Document Type: Article

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22. 4. The solvent was removed in vacuo. The crude reaction mixture was purified by flash chromatography over silica gel eluting with EtOAC-light petroleum (bp 40-60 °C), 1 : 9 to give the desired product (0.48 g, 78%). The aqueous layer contains the quinuclidine N-oxide.