The highly stereoselective formation of pipecolic acid N-oxide and related derivatives

Tetrahedron Letters

Volumn 38, Issue 32, 1997, Pages 5731-5734

  O'Neil, Ian A ^a   Potter, Andrew J ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PIPECOLIC ACID DERIVATIVE;

ARTICLE; DRUG STABILITY; DRUG SYNTHESIS; IN VITRO STUDY; OXIDATION; REACTION ANALYSIS; STEREOISOMERISM;

EID: 0030812215     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01258-6     Document Type: Article

References (9)

1. O'Neil, I. A.; Miller, N. D.; Peake, J.; Barkley, J. V.; Low, C. M. R.; Kalindjian, S. B. Synlett., 1993, 515. O'Neil, I. A.; Miller, N. D.; Barkley, J. V.; Low, C. M. R.; Kalindjian, S. B. Synlett., 1995, 617 and 619.
2. O'Neil, I. A.; Miller, N. D.; Peake, J.; Barkley, J. V.; Low, C. M. R.; Kalindjian, S. B. Synlett., 1993, 515. O'Neil, I. A.; Miller, N. D.; Barkley, J. V.; Low, C. M. R.; Kalindjian, S. B. Synlett., 1995, 617 and 619.
3. O'Neil, I. A.; Turner, C. D.; Kalindjian, S. B. Synlett, 1997, 777.
4. Racemic pipecolic acid was used in this study; all compounds described are racemic. Relative stereochemistry is shown in all diagrams.
5. We thank J. V. Barkley for this structure determination. Full crystallographic data will be deposited at the Cambridge Crystallographic Database.
6. Shvo, Y.; Kaufman, E. D. Tetrahedron, 1972, 28, 573. Shvo, Y.; Kaufman, E. D. J. Org. Chem., 1981, 46, 2148. Kawazoe, Y.; Tsuda, M. Chem. Pharm. Bull., 1967, 15, 1405. Cook, M. J.; Katritzky, A. R.; Manas, M. M. J. Chem. Soc. (B)., 1971, 1330.
7. Shvo, Y.; Kaufman, E. D. Tetrahedron, 1972, 28, 573. Shvo, Y.; Kaufman, E. D. J. Org. Chem., 1981, 46, 2148. Kawazoe, Y.; Tsuda, M. Chem. Pharm. Bull., 1967, 15, 1405. Cook, M. J.; Katritzky, A. R.; Manas, M. M. J. Chem. Soc. (B)., 1971, 1330.
8. Shvo, Y.; Kaufman, E. D. Tetrahedron, 1972, 28, 573. Shvo, Y.; Kaufman, E. D. J. Org. Chem., 1981, 46, 2148. Kawazoe, Y.; Tsuda, M. Chem. Pharm. Bull., 1967, 15, 1405. Cook, M. J.; Katritzky, A. R.; Manas, M. M. J. Chem. Soc. (B)., 1971, 1330.
9. Shvo, Y.; Kaufman, E. D. Tetrahedron, 1972, 28, 573. Shvo, Y.; Kaufman, E. D. J. Org. Chem., 1981, 46, 2148. Kawazoe, Y.; Tsuda, M. Chem. Pharm. Bull., 1967, 15, 1405. Cook, M. J.; Katritzky, A. R.; Manas, M. M. J. Chem. Soc. (B)., 1971, 1330.