Synthesis and structure activity relationships of novel small molecule cathepsin D inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 17, 1999, Pages 2531-2536

  Dumas, Jacques ^a   Brittelli, David ^a   Chen, Jinshan ^a   Dixon, Brian ^a   Holia, Hatoum Mokdad ^a   König, Gerhard ^b   Sibley, Robert ^a   Witowsky, James ^b   Wong, Stephen ^b  

^a Department of Chemistry Research ^*  (United States)

^b BAYER CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MERCAPTOBENZOTHIAZOLE; AMIDE; ANILINE; ASPARTIC PROTEINASE INHIBITOR; CARBOXYLIC ACID DERIVATIVE; CATHEPSIN D; CHLOROPHENOL; NITROBENZENE DERIVATIVE; PHENOL; PYRIDINE; SULFONAMIDE;

ALZHEIMER DISEASE; ARTICLE; BREAST CANCER; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; LIVER; OVARY CANCER; STRUCTURE ACTIVITY RELATION;

CATHEPSIN D; HUMANS; LIVER; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033530132     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00433-3     Document Type: Article

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