Synthesis of a transition state analogue for the hydrolysis of cocaine: Assistance to phosphonylation of a 3β-hydroxytropane by a neighbouring amide group

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 13, 1999, Pages 1881-1884

  Hagi Pavli, Eleni P ^a   Simms, Caroline S ^b   Ostler, Elizabeth L ^b   Brocklehurst, Keith ^a   Gallacher, Gerard ^b  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF BRIGHTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA HYDROXYTROPANE; COCAINE; PHOSPHONIC ACID DERIVATIVE; PHOSPHONIC ACID ESTER; TROPANE DERIVATIVE; TROPINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; HYDROLYSIS; REACTION ANALYSIS; SYNTHESIS;

AMIDES; COCAINE; HYDROLYSIS; PHOSPHONIC ACIDS; TIME FACTORS; TROPANES;

EID: 0033526915     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00293-0     Document Type: Article

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