Retrovirus DNA termini bound by integrase communicate in trans for full- site integration in vitro

Virology

Volumn 259, Issue 2, 1999, Pages 392-401

  McCord, Mark ^a   Chiu, Roger ^a   Vora, Ajaykumar C ^a   Grandgenett, Duane P ^a  

^a SAINT LOUIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE; VIRUS DNA;

ALLOSTERISM; ARTICLE; AVIAN MYELOBLASTOSIS VIRUS; BINDING AFFINITY; DNA INTEGRATION; DNA STRAND; DNA TRANSFER; GENE MUTATION; HALF LIFE TIME; LONG TERMINAL REPEAT; PRIORITY JOURNAL; RETROVIRUS; VIRUS ASSEMBLY; VIRUS DNA CELL DNA INTERACTION;

AVES; AVIAN MYELOBLASTOSIS VIRUS; AVIAN RETROVIRUS; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0033526841     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.9782     Document Type: Article

References (33)

1. Aiyar N., Hindmarsh P., Skalka A. M., Leis J. Concerted integration of linear retroviral DNA by the avian sarcoma virus integrase in vitro: Dependence on both long terminal repeat termini. J. Virol. 70:1996;3571-3580.
2. Balakrishnan M., Jonsson C. B. Functional identification of nucleotides conferring substrate specificity of retroviral integrase reactions. J. Virol. 71:1997;1025-1035.
3. Brown P. 0. Integration. Coffin J. M., Hughes S. J., Varmus H. E. Retroviruses. 1998;161-203 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
4. Brown P. 0., Bowerman B., Varmus H. E., Bishop J. M. Correct integration of retroviral DNA in vitro. Cell. 49:1987;347-356.
5. Cobrinik D., Aiyar A. Ge, Z. Katzman, M. Huang, J. and Leis. Overlapping retrovirus U5 sequence elements are required for efficient integration and initiation of reverse transcription. J. Virol. 65:1991;3864-3872.
6. Ellison V., Brown P. O. A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro. Proc. Nati. Acad. Sci. USA. 91:1994;7316-7320.
7. Ellison V., Gerton J., Vincent K. A., Brown P. O. An essential interaction between distinct domains of HIV-1 integrase mediates assembly of the active multimer. J. Biol. Chem. 270:1995;3320-3326.
8. Farnet C. M., Haseltine W. A. Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex. J. Virol. 65:1991;1910-1915.
9. Fujiwara T., Mizuuchi K. Retroviral DNA integration: structure of a integration intermediate. Cell. 54:1988;497-504.
10. Goff S. P. Genetics of retroviral integration. Annu. Rev. Genet. 26:1992;527-544.
11. Grandgenett D. P., Inman R., Vora A. C., Fitzgerald M. Comparison of DNA binding and integration half-site selection by avian myeloblastosis virus integrase. J. Virol. 67:1993;2628-2636.
12. Grandgenett D. P., Vora A. C., Schiff R. A 32000-dalton nucleic acid-binding protein from avian retrovirus cores possesses DNA endonuclease activity. Virology. 89:1978;119-132.
13. Jones K. S., Coleman J., Merkel G., Laue T. M., Skalka A. M. Retroviral integrase functions as a multimer and can turn over catalytically. J. Biol. Chem. 287:1992;16037-16040.
14. Kulkosky J., Skalka A. M. Molecular mechanism of retroviral DNA integration. Pharmacol. Ther. 61:1994;185-203.
15. Knaus R. J., Hippenmeyer P. J., Misra T. M., Grandgenett D. P., Muller R., Fitch W. M. Avian retrovirus pp32 DNA binding protein: Preferential binding to the promoter region of long terminal repeat DNA. Biochemistry. 23:1984;350-359.
16. Lee Y. M. H., Coffin J. M. Relationship of avian retrovirus DNA synthesis to integration in vitro. Mol. Cell. Biol. 11:1991;1419-1430.
17. Li L., Farnet C. M., Anderson W. F., Bushman F. D. Modulation of activity of Moloney murine leukemia virus preintegration complexes by host factors in vitro. J. Virol. 72:1998;2125-2131.
18. Masuda T., Kuroda M. J., Harada S. Specific and independent recognition of U3 and U5 att sites by human immunodeficiency virus type 1 integrase in vitro. J. Virol. 72:1998;8396-8402.
19. McCord M., Stahl J., Mueser T. C., Hyde C. C., Vora A. C., Grandgenett D. P. Purification of recombinant Rous sarcoma virus integrase possessing physical and catalytic properties similar to virion-derived integrase. Prot. Purif. Expression. 14:1998;167-177.
20. Miller M. D., Farnet C. M., Bushman F. D. Human immunodeficiency virus type 1 preintegration complexes: Studies of organization and composition. J. Virol. 71:1997;5382-5390.
21. Miller J. T., Ge Z., Morris S., Das K., Leis J. Multiple biological roles associated with the Rous sarcoma virus 5′ untranslated RNA U5-IR stem and loop. J. Virol. 71:1997;7648-7656.
22. Mizuuchi K. Polynucleotidyl transfer reactions in transpositional DNA recombination. J. Biol. Chem. 30:1992;21273-21276.
23. Murphy J. E., Goff S. P. A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo. J. Virol. 66:1992;5092-5095.
24. Record M. T., Ha J. H., Fisher M. Analysis of equilibrium and kinetic measurements to determine thermodynamic origins of stability, specificity and mechanism of formation of site-specific complexes between proteins and helical DNA. Methods Enzymol. 208:1991;291-343.
25. Reicin A. S., Kalpana G., Paik S., Marmon S., Goff S. P. Sequences in the human immunodeficiency virus type 1 U3 region required for in vivo and in vitro integration. J. Virol. 69:1995;5904-5907.
26. Scottoline B. P., Chow S., Ellison V., Brown P. O. Disruption of the terminal base pairs of retroviral DNA during integration. Genes Dev. 11:1997;371-382.
27. Vink C., Plasterk R. H. A. The human immunodeficiency virus integrase protein. Trends Genet. 9:1993;433-438.
28. Vora A. C., Grandgenett D. P. Assembly and catalytic properties of retrovirus integrase-DNA complexes capable of efficiently performing concerted integration. J. Virol. 69:1995;7483-7488.
29. Vora A. C., McCord M., Fitzgerald M., Inman R. B., Grandgenett D. P. Efficient concerted integration of retrovirus-like DNA in vitro by avian myeloblastosis virus integrase. Nucleic Acids Res. 22:1994;4454-4461.
30. Vora A. C., McCord M., Goodarzi G., Stahl S. J., Mueser T. C., Hyde C. C., Grandgenett D. P. Avian retrovirus U3 and U5 DNA inverted repeats: role of nonsymmetrical nucleotides in promoting full-site integration by purified virion and bacterial recombinant integrases. J. Biol. Chem. 272:1997;23938-23945.
31. Wei S. Q., Mizuuchi K., Craigie R. A large nucleoprotein assembly at the viral DNA mediates retroviral DNA integration. EMBO J. 16:1997;7511-7520.
32. Wei S. Q., Mizuuchi K., Craigie R. Footprints on the viral DNA ends in Moloney murine leukemia virus preintegration complexes reflect a specific association with integrase. Pro. Natl. Acad. Sci. USA. 95:1998;10535-10540.
33. Yoshinaga T., Fujiwara T. Different roles of bases within the integration signal sequence of human immunodeficiency virus type 1 in vitro. J. Virol. 69:1995;3233-3236.