Use of site-specific mutagenesis and monoclonal antibodies to map regions of CD46 that interact with measles virus H protein

Virology

Volumn 258, Issue 2, 1999, Pages 314-326

  Hsu, Eric C ^a,b   Sabatinos, Sarah ^a,b   Hoedemaeker, Flip J ^a,c   Rose, David R ^a,c   Richardson, Christopher D ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b AMGEN INC   (United States)

^c PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE COFACTOR PROTEIN; MONOCLONAL ANTIBODY;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONSENSUS SEQUENCE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MEASLES VIRUS; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS;

EID: 0033526510     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.9712     Document Type: Article

References (44)

1. Arthos J., Deen K. C., Chaikin M. A., Fornwald J. A., Sathe G., Sattentau Q. J., Clapham P. R., Weiss R. A., McDougal J. S., Pietropaolo C., Axel R., Truneh A., Maddon P. J., Sweet R. W. Identification of the residues in human CD4 critical for the binding of HIV. Cell. 57:1989;469-481.
2. Ashkenazi A., Presta L. G., Marsters S. A., Camerato T. R., Rosenthal K. A., Fendly B. M., Capon D. J. Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis. Proc. Natl. Acad. Sci. USA. 87:1990;7150-7154.
3. Barlow P., Steinkasserer A., Norman D. B., Kieffer B., Wiles A. P., Sim R. B., Campbell I. D. Solution structure of a pair of complement modules by nuclear magnetic resonance. J. Mol. Biol. 232:1993;268-284.
4. Bowman M. R., MacFerrin K. D., Schreiber S. L., Burakoff S. J. Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules. Proc. Natl. Acad. Sci. USA. 87:1990;9052-9056.
5. Brodsky M. H., Warton M., Myers R. M., Littman D. R. Analysis of the site in CD4 that binds to the HIV envelope glycoprotein. J. Immunol. 144:1990;3078-3086.
6. Buchholz C. J., Koller D., Devaux P., Mumenthaler C., Schneider-Schaullies J., Braun W., Gerlier D., Cattaneo R. Mapping of the primary binding site of measles virus to its receptor CD46. J. Biol. Chem. 272:1997;22072-22079.
7. Buchholz C. J., Schneider U., Devaux P., Gerlier D., Cattaneo R. Cell entry by measles virus: Long hybrid receptors uncouple binding from membrane fusion. J. Virol. 70:1996;3716-3723.
8. Clarkson N. A., Kaufman R., Lublin R. M., Ward T., Pipkin P. A., Minor P. D., Evans D. J., Almond J. W. Characterization of the echovirus 7 receptor: domains of CD55 critical for virus binding. J. Virol. 69:1995;5497-5501.
9. Clayton L. K., Hussey R. E., Steinbrich R., Ramachandran H., Husain V., Reinherz E. L. Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding. Nature. 335:1988;363-366.
10. Clements C. J., Cutts F. T. The epidemiology of measles: Thirty years of vaccination. ter Meulen V., Billeter M. A. Measles Virus. 1995;13-33 Springer-Verlag, Berlin.
11. Dörig R. E., Marcil A., Chopra A., Richardson C. D. The human CD46 is a receptor for measles virus (Edmonston strain). Cell. 75:1993;295-305.
12. Dörig R. E., Marcil A., Richardson C. D. CD46, a primate-specific receptor for measles virus. Trends Microbiol. 2:1994;312-318.
13. Earl P. L., Elroy-Stein O., Moss B. Expression of proteins in mammalian cells using vaccinia viral vectors. Ausabel F. M., Brent R., Kingston R. E., Moore D. D., Seidman J. G., Smith J. A., Struhl K. Current Protocols in Molecular Biology. 1995;16.15-16.19 J. Wiley & Sons, New York.
14. Enders J. F. Measles virus: Historical review, isolation and behaviour in various systems. Am. J. Dis. Child. 103:1962;282-287.
15. Gerlier D., Varior-Krishnan G., Devaux P. CD46-mediated virus entry: a first key to host-range specificity. Trends Microbiol. 3:1995;338-345.
16. Hilleman M. R., Buynak E. B., Weibel R. E., Stokes J., Whitman J. E., Leagus M. B. Development and evaluation of the Moraten measles virus vaccine. JAMA. 206:1968;587.
17. Hsu E. C., Dörig R. E., Sarangi F., Marcil F., Iorio C., Richardson C. D. Artificial mutations and natural variations in the CD46 molecules from human and monkey cells define regions important for measles virus binding. J. Virol. 71:1997;6144-6154.
18. Iwata K., Seya T., Yanagi Y., Pesando J. M., Johnson P. M., Okabe M., Ueda S., Ariga H., Nagasawa S. Diversity of sites for measles virus binding and for inactivation of complement C3b and C4b on membrane cofactor protein CD46. J. Biol. Chem. 270:1995;15148-15152.
19. Jameson B. A., Rao P. E., Kong L. I., Hahn B. H., Shaw G. M., Hood L. E., Kent S. B. H. Location and chemical synthesis of a binding site for HIV-1 on the CD4 protein. Science. 240:1988;1335-1339.
20. Kuttner-Kondo L., Medof M. E., Brodbeck W., Shoham M. Molecular modeling and mechanism of action of human decay-accelerating factor. Prot. Eng. 9:1996;1143-1149.
21. Kwong P. D., Watt R., Robinson J., Sweet R. W., Sodroski J., Hendrickson W. A. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature. 393:1998;648-659.
22. Lalumiére M., Richardson C. D. Production of recombinant baculoviruses using rapid screening vectors that contain the gene for β-galactosidase. Richardson C. D. Baculovirus Expression Protocols. 1995;161-177 Humana Press, Totowa.
23. Levy J. A. HIV and the Pathogenesis of AIDS. 1994;ASM Press, Washington. p. 35-36.
24. Liszewski M. K., Atkinson J. P. Membrane cofactor protein. Curr. Topics Microbiol. Immunol. 178:1992;45-60.
25. Liszewski M. K., Post T. W., Atkinson J. P. Membrane cofactor protein (MCP of CD46): Newest member of the regulators of complement activation gene cluster. Annu. Rev. Immunol. 9:1991;431-455.
26. Maisner A., Herrler G. Membrane cofactor protein with different types of N-glycans can serve as measles virus receptor. Virology. 210:1995;479-481.
27. Maisner A., Liszewski M. K., Atkinson J. P., Herrler G. Oligosaccharide in SCR-2 is required for measles virus binding and infection. J. Virol. 70:1996;4973-4977.
28. Manchester M., Gairin J. E., Patterson J. B., Alvarez J., Liszewski M. K., Eto D. S., Atkinson J. P., Oldstone M. B. Measles virus recognizes its receptor, CD46, via two distinct binding domains within SCR1-2. Virology. 233:1997;174-184.
29. Manchester M., Valsamakis A., Kaufman R., Liszewski M. K., Alvarez J., Atkinson J. P., Lublin D. M., Oldstone M. B. A. Measles virus and C3 binding sites are distinct on membrane cofactor protein (CD46). Proc. Natl. Acad. Sci. USA. 92:1995;2303-2307.
30. Mizukami T., Fuerst T. R., Berger E. A., Moss B. Binding region for human immunodeficiency virus (HIV) and epitopes for HIV-blocking monoclonal antibodies of the CD4 molecule defined by site-directed mutagenesis. Proc. Natl. Acad. Sci. USA. 85:1988;9273-9277.
31. Moore M. D., Cannon M.J, Sewall A., Finlayson M., Okimoto M., Nemerow G. R. Inhibition of Epstein-Barr virus infection in vitro and in vivo by soluble CR2 (CD21) containing two short consensus repeats. J. Virol. 65:1991;3559-3565.
32. Mumenthaler C., Schneider, Buchholz C. J., Koller D., Braun W., Cattaneo R. A 3D model for the measles virus receptor CD46 based on homology modeling, Monte Carlo simulations, and hemagglutinin binding studies. Prot. Sci. 6:1997;588-597.
33. Naniche D., Varior-Krishnan G., Cervoni F., Wild T. F., Rossi B., Rabourdin-Combe C., Gerlier D. Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus. J. Virol. 67:1993;6025-6032.
34. Peterson A., Seed B. Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4. Cell. 54:1988;65-72.
35. Repke H., Gabuzda D., Palu G., Emmrich R., Sodrosky J. Effect of CD4 synthetic peptides on HIV type 1 envelope glycoprotein function. J. Immunol. 149:1992;1809-1816.
36. Richardson C. D., Banville M., Lalumiére M., Vialard J., Meighen E. A. Bacterial luciferase produced with rapid screening baculovirus vectors is a sensitive reporter for infection of insect cells and larvae. Intervirology. 34:1992;213-227.
37. Rota J. S., Hummel K. B., Rota P. A., Bellini W. J. Genetic variability of the glycoprotein genes of current wild-type measles isolates. Virology. 188:1992;135-142.
38. Sattentau Q. J., Dalgleish A. G., Weiss R. A., Beverley P. C. L. Epitopes of the CD4 antigen and HIV infection. Science. 234:1986;1120-1123.
39. Seya T., Kurita M., Hara T., Iwata K., Semba, Hatanaka M., Matsumoto M., Yanagi Y., Ueda S., Nagasawa S. Blocking measles virus infection with a recombinant soluble form of, or monoclonal antibodies against, membrane cofactor protein of complement (CD46). Immunology. 84:1995;619-625.
40. Tsui P., Sweet R. W., Sathe G., Rosenberg M. An efficient phage plaque screen for the random mutational analysis of the interaction of HIV-1 gp120 with human CD4. J. Biol. Chem. 267:1992;9361-9367.
41. Vialard J., Lalumiere M., Vernet T., Briedis D., Alkhatib G., Henning D., Levin D., Richardson C. D. Synthesis of the membrane fusion and hemagglutinin proteins of measles virus, using a novel baculovirus vector containing the β-galactosidase gene. J. Virol. 64:1990;37-50.
42. Vialard J. E., Richardson C. D. The 1629-nucleotide open reading frame located downstream of the Autographa californica nuclear polyhedrosis virus polyhedrin gene encodes a nucleocapsid-associated phosphoprotein. J. Virol. 67:1993;5859-5866.
43. Weiss R. Measles battle loses potent weapon. Science. 258:1992;546-547.
44. Zhang X., Gaubin M., Briant L., Srikantan V., Murali R., Saragovi U., Weiner D., Devaux C., Autiero M., Piatier-Tonneau D., Greene M. I. Synthetic CD4 exocyclics inhibit binding of human immunodeficiency virus type 1 envelope to CD4 and virus replication in T lymphocytes. Nat. BioTechniques. 15:1997;150-154.