-
1
-
-
0348232540
-
-
Lalwani, N. D.; Alveres, K.; Reddy, M. K.; Reddy, M. N.; Parikh, L.; Reddy, J. K. Proc. Natl. Acad. Sci. U.S.A. 1987, 84, 5242.
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 5242
-
-
Lalwani, N.D.1
Alveres, K.2
Reddy, M.K.3
Reddy, M.N.4
Parikh, L.5
Reddy, J.K.6
-
2
-
-
0030062325
-
-
Willson, T. M.; Cobb, J. E.; Cowan, D. J.; Wiethe, R. W.; Correa, I. D.; Prakash, S. R.; Beck, K. D.; Moore, L. B.; Kliewer, S. A.; Lehmann, J. M J. Med. Chem. 1996, 39, 665.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 665
-
-
Willson, T.M.1
Cobb, J.E.2
Cowan, D.J.3
Wiethe, R.W.4
Correa, I.D.5
Prakash, S.R.6
Beck, K.D.7
Moore, L.B.8
Kliewer, S.A.9
Lehmann, J.M.10
-
3
-
-
0029016829
-
-
Lehmann, J. M.; Moore, L. B.; Smith-Oliver, T. A.; Wilkison, W. O.; Willson, T. M.; Kliewer, S. A. J. Biol. Chem. 1995, 270, 12953.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
4
-
-
0027447461
-
-
Keller, H.; Dreyer, C.; Medin, J.; Mahfoudi, A.; Ozato, K.; Wahli, W. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 2160.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 2160
-
-
Keller, H.1
Dreyer, C.2
Medin, J.3
Mahfoudi, A.4
Ozato, K.5
Wahli, W.6
-
5
-
-
0028972025
-
-
Forman, B. M.; Tontonoz, P.; Chen, J.; Brun, R. P.; Spiegelman, B. M.; Evans, R. M. Cell 1995, 83, 803.
-
(1995)
Cell
, vol.83
, pp. 803
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
6
-
-
0029294531
-
-
Wahli, W.; Braissant, O.; Desvergne, B. Chem. Biol. 1995, 2, 261.
-
(1995)
Chem. Biol.
, vol.2
, pp. 261
-
-
Wahli, W.1
Braissant, O.2
Desvergne, B.3
-
7
-
-
0028838714
-
-
Rosen, J.; Day, A.; Jones, T. K.; Jones, T. T.; Nadzan, A. M.; Stein, R. B. J. Med. Chem. 1995, 38, 4855.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4855
-
-
Rosen, J.1
Day, A.2
Jones, T.K.3
Jones, T.T.4
Nadzan, A.M.5
Stein, R.B.6
-
8
-
-
0030798273
-
-
This work was first presented at the 215th National Meeting of the American Chemical Society, Dallas, Texas, April, 1998. During our investigation toward the preparation of BRL 49653 on the solid support, another study involving the preparation of a library of thiazolidinedione - fatty acid PPARγ ligands was reported. This approach assembled subunits A, B, and C, using standard solution-phase techniques, and then attached the functionalized thiazolidinedione to a 2-chlorotrityl chloride resin. This functionalized thiazolidinedione (TZD) was then diversified on the support by coupling the supported TZD with a variety of straight-chain alkyl-and alkenyl-carboxylic acids. Tomkinson, N. C. O.; Sefler, A. M.; Plunket, K. D.; Blanchard, S. G.; Parks, D. J.; Willson, T. M. Bioorg. Med. Chem. Lett. 1997, 7, 2491. In addition, the polymer-supported synthesis of 4-thiazolidinones derived from amino acids has been reported, and a library of analogues have been prepared. Holmes, C. P.; Chinn, J. P.; Look, G. C.; Gordon E. M.; Gallop, M. A. J. Org. Chem. 1995, 60, 7328.
-
(1997)
Bioorg. Med. Chem. Lett.
, vol.7
, pp. 2491
-
-
Tomkinson, N.C.O.1
Sefler, A.M.2
Plunket, K.D.3
Blanchard, S.G.4
Parks, D.J.5
Willson, T.M.6
-
9
-
-
0000058677
-
-
This work was first presented at the 215th National Meeting of the American Chemical Society, Dallas, Texas, April, 1998. During our investigation toward the preparation of BRL 49653 on the solid support, another study involving the preparation of a library of thiazolidinedione - fatty acid PPARγ ligands was reported. This approach assembled subunits A, B, and C, using standard solution-phase techniques, and then attached the functionalized thiazolidinedione to a 2-chlorotrityl chloride resin. This functionalized thiazolidinedione (TZD) was then diversified on the support by coupling the supported TZD with a variety of straight-chain alkyl-and alkenyl-carboxylic acids. Tomkinson, N. C. O.; Sefler, A. M.; Plunket, K. D.; Blanchard, S. G.; Parks, D. J.; Willson, T. M. Bioorg. Med. Chem. Lett. 1997, 7, 2491. In addition, the polymer-supported synthesis of 4-thiazolidinones derived from amino acids has been reported, and a library of analogues have been prepared. Holmes, C. P.; Chinn, J. P.; Look, G. C.; Gordon E. M.; Gallop, M. A. J. Org. Chem. 1995, 60, 7328.
-
(1995)
J. Org. Chem.
, vol.60
, pp. 7328
-
-
Holmes, C.P.1
Chinn, J.P.2
Look, G.C.3
Gordon, E.M.4
Gallop, M.A.5
-
10
-
-
0025032015
-
-
Albericio, F.; Kneib-Cordonier, N.; Biancalana, S.; Gera, L.; Masada, R. I.; Hudson, D.; Barany, G. J. Org. Chem. 1990, 55, 3730. Landi, J. J., Jr.; Ramig, K. Synth. Commun. 1991, 21, 167. Carvalho, C. F.; Sargent, M. V. J. Chem. Soc., Perkin Trans. 1 1984, 1605.
-
(1990)
J. Org. Chem.
, vol.55
, pp. 3730
-
-
Albericio, F.1
Kneib-Cordonier, N.2
Biancalana, S.3
Gera, L.4
Masada, R.I.5
Hudson, D.6
Barany, G.7
-
11
-
-
0025872821
-
-
Albericio, F.; Kneib-Cordonier, N.; Biancalana, S.; Gera, L.; Masada, R. I.; Hudson, D.; Barany, G. J. Org. Chem. 1990, 55, 3730. Landi, J. J., Jr.; Ramig, K. Synth. Commun. 1991, 21, 167. Carvalho, C. F.; Sargent, M. V. J. Chem. Soc., Perkin Trans. 1 1984, 1605.
-
(1991)
Synth. Commun.
, vol.21
, pp. 167
-
-
Landi, J.J.J.1
Ramig, K.2
-
12
-
-
2742587368
-
-
Albericio, F.; Kneib-Cordonier, N.; Biancalana, S.; Gera, L.; Masada, R. I.; Hudson, D.; Barany, G. J. Org. Chem. 1990, 55, 3730. Landi, J. J., Jr.; Ramig, K. Synth. Commun. 1991, 21, 167. Carvalho, C. F.; Sargent, M. V. J. Chem. Soc., Perkin Trans. 1 1984, 1605.
-
(1984)
J. Chem. Soc., Perkin Trans. 1
, pp. 1605
-
-
Carvalho, C.F.1
Sargent, M.V.2
-
13
-
-
0030932342
-
-
Boojamra, C. G.; Burow, K. M.; Thompson, L. A.; Ellman, J. A. J. Org. Chem. 1997, 62, 1240.
-
(1997)
J. Org. Chem.
, vol.62
, pp. 1240
-
-
Boojamra, C.G.1
Burow, K.M.2
Thompson, L.A.3
Ellman, J.A.4
-
14
-
-
0031575637
-
-
Gray, N. S.; Kwon, S.; Schultz, P. G. Tetrahedron Lett. 1997, 38, 1161.
-
(1997)
Tetrahedron Lett.
, vol.38
, pp. 1161
-
-
Gray, N.S.1
Kwon, S.2
Schultz, P.G.3
-
15
-
-
0000574417
-
-
For preparation, see: Castro, J. L.; Matassa, V. G.; Ball, R. G. J. Org. Chem. 1994, 59, 2289. For application in SPOC, see: Swayze, E. E. Tetrahedron Lett. 1997, 38, 8465.
-
(1994)
J. Org. Chem.
, vol.59
, pp. 2289
-
-
Castro, J.L.1
Matassa, V.G.2
Ball, R.G.3
-
16
-
-
0030680993
-
-
For preparation, see: Castro, J. L.; Matassa, V. G.; Ball, R. G. J. Org. Chem. 1994, 59, 2289. For application in SPOC, see: Swayze, E. E. Tetrahedron Lett. 1997, 38, 8465.
-
(1997)
Tetrahedron Lett.
, vol.38
, pp. 8465
-
-
Swayze, E.E.1
-
17
-
-
0344437814
-
-
note
-
Lower chemical yields were obtained as a result of the formation of significant amounts of byproducts resulting from the coupling reaction between the substrate and DEAD.
-
-
-
-
18
-
-
0027988554
-
-
Cantello, B. C. C.; Cawthorne, M. A.; Cottam, G. P.; Duff, P. T.; Haigh, D.; Hindley, R. M.; Lister, C. A.; Smith, S. A.; Thurlby, P. L. J. Med. Chem. 1994, 37, 3977.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 3977
-
-
Cantello, B.C.C.1
Cawthorne, M.A.2
Cottam, G.P.3
Duff, P.T.4
Haigh, D.5
Hindley, R.M.6
Lister, C.A.7
Smith, S.A.8
Thurlby, P.L.9
-
19
-
-
0030987008
-
-
Bolton, G. L. Tetrahedron Lett. 1997, 53, 6611. Koenig, T. M.; Daeuble, J. F.; Brestensky, D. M.; Stryker, J. M. Tetrahedron Lett. 1990, 31, 3237. Brestensky, D. M.; Huseland, D. E.; McGettigan, C.; Stryker, J. M. Tetrahedron Lett. 1988, 29, 3749. Mahoney, W. S.; Brestensky, D. M.; Stryker, J. M. J. Am. Chem. Soc. 1988, 110, 291.
-
(1997)
Tetrahedron Lett.
, vol.53
, pp. 6611
-
-
Bolton, G.L.1
-
20
-
-
0025346212
-
-
Bolton, G. L. Tetrahedron Lett. 1997, 53, 6611. Koenig, T. M.; Daeuble, J. F.; Brestensky, D. M.; Stryker, J. M. Tetrahedron Lett. 1990, 31, 3237. Brestensky, D. M.; Huseland, D. E.; McGettigan, C.; Stryker, J. M. Tetrahedron Lett. 1988, 29, 3749. Mahoney, W. S.; Brestensky, D. M.; Stryker, J. M. J. Am. Chem. Soc. 1988, 110, 291.
-
(1990)
Tetrahedron Lett.
, vol.31
, pp. 3237
-
-
Koenig, T.M.1
Daeuble, J.F.2
Brestensky, D.M.3
Stryker, J.M.4
-
21
-
-
0001324442
-
-
Bolton, G. L. Tetrahedron Lett. 1997, 53, 6611. Koenig, T. M.; Daeuble, J. F.; Brestensky, D. M.; Stryker, J. M. Tetrahedron Lett. 1990, 31, 3237. Brestensky, D. M.; Huseland, D. E.; McGettigan, C.; Stryker, J. M. Tetrahedron Lett. 1988, 29, 3749. Mahoney, W. S.; Brestensky, D. M.; Stryker, J. M. J. Am. Chem. Soc. 1988, 110, 291.
-
(1988)
Tetrahedron Lett.
, vol.29
, pp. 3749
-
-
Brestensky, D.M.1
Huseland, D.E.2
McGettigan, C.3
Stryker, J.M.4
-
22
-
-
33845278094
-
-
Bolton, G. L. Tetrahedron Lett. 1997, 53, 6611. Koenig, T. M.; Daeuble, J. F.; Brestensky, D. M.; Stryker, J. M. Tetrahedron Lett. 1990, 31, 3237. Brestensky, D. M.; Huseland, D. E.; McGettigan, C.; Stryker, J. M. Tetrahedron Lett. 1988, 29, 3749. Mahoney, W. S.; Brestensky, D. M.; Stryker, J. M. J. Am. Chem. Soc. 1988, 110, 291.
-
(1988)
J. Am. Chem. Soc.
, vol.110
, pp. 291
-
-
Mahoney, W.S.1
Brestensky, D.M.2
Stryker, J.M.3
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