N2-hydroxyguanosine 5'-monophosphate is a time-dependent inhibitor of Escherichia coli guanosine monophosphate synthetase

Biochemistry

Volumn 38, Issue 1, 1999, Pages 303-310

  Deras, Michael L ^a,b   Chittur, Sridar V ^b   Davisson, V Jo ^b  

^a Bldg 142   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; ENZYME INHIBITOR; GUANOSINE PHOSPHATE; SYNTHETASE; 2 FLUOROADENOSINE; 2-FLUOROADENOSINE; 7 HYDROXYGUANOSINE 5' MONOPHOSPHATE; 7-HYDROXYGUANOSINE 5'-MONOPHOSPHATE; ADENOSINE; ADENOSINE TRIPHOSPHATE; DRUG DERIVATIVE; GLUTAMINASE; GUANOSINE PHOSPHATE SYNTHASE (GLUTAMINE HYDROLYSING); LIGASE;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; ENZYME ANALYSIS; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; CHEMICAL MODEL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; HYDROLYSIS; KINETICS;

5'-GUANYLIC ACID; ADENOSINE; ADENOSINE TRIPHOSPHATE; CARBON-NITROGEN LIGASES WITH GLUTAMINE AS AMIDE-N-DONOR; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUTAMINASE; HYDROLYSIS; KINETICS; MODELS, CHEMICAL;

EID: 0033524225     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981980r     Document Type: Article

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