Total synthesis of (+)-halichlorine: An inhibitor of VCAM-1 expression

Angewandte Chemie - International Edition

Volumn 38, Issue 23, 1999, Pages 3542-3545

  Trauner, Dirk ^a   Schwarz, Jacob B ^a   Danishefsky, Samuel J ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Department of Chemistry Columbia University Havemeyer Hall ^*  (United States)

Author keywords

Alkaloids; C C coupling; Natural products; Organozinc compounds; Total synthesis

Indexed keywords

ALDEHYDE; AMINOALCOHOL; CHLORINE DERIVATIVE; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CHEMICAL BINDING; CHEMICAL REACTION; CHEMICAL STRUCTURE; DIASTEREOISOMER; STEREOCHEMISTRY; SYNTHESIS;

EID: 0033521184     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19991203)38:23<3542::AID-ANIE3542>3.0.CO;2-I     Document Type: Article

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41. We thank Professor D. Uemura and Dr. H. Arimoto for kindly providing us with halichlorine and its associated spectra as well as spectra of its methanolysis product.