Mutations uncouple human fibroblast growth factor (FGF)-7 biological activity and receptor binding and support broad specificity in the secondary receptor binding site of FGFs

Journal of Biological Chemistry

Volumn 274, Issue 49, 1999, Pages 35016-35022

  Sher, Ifat ^a   Weizman, Alexander ^a   Lubinsky Mink, Sharon ^a   Lang, Tamar ^a   Adir, Noam ^a   Schomburg, Dietmar ^b   Ron, Dina ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; TYROSINE KINASE RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL SPECIFICITY; CHEMICAL MUTAGENESIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

3T3 CELLS; ANIMALS; BINDING SITES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 7; FIBROBLAST GROWTH FACTORS; GROWTH SUBSTANCES; HUMANS; KINETICS; MICE; MODELS, MOLECULAR; MUTAGENESIS; PHOSPHORYLATION; POINT MUTATION; PROTEIN BINDING; PROTEIN ISOFORMS; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; TEMPERATURE; TYROSINE;

EID: 0033521108     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.49.35016     Document Type: Article

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