Cell-cycle inhibitor p27/Kip-1 expression in non-astrocytic and non- oligodendrocytic human nervous system tumors

Neuroscience Letters

Volumn 264, Issue 1-3, 1999, Pages 29-32

  Schiffer, D ^a   Bortolotto, S ^a   Bosone, I ^a   Cancelli, I ^a   Cavalla, P ^a   Schiffer, P ^a   Piva, R ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Immunohistochemistry; Nervous system tumors; p27 kip 1

Indexed keywords

PROTEIN P27;

ARTICLE; CELL CYCLE; CELL PROLIFERATION; GLIOMA; HUMAN; HUMAN TISSUE; MEDULLOBLASTOMA; MENINGIOMA; NERVOUS SYSTEM TUMOR; NEURILEMOMA; NEUROBLASTOMA; OLIGODENDROGLIA; PRIORITY JOURNAL;

APOPTOSIS; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; EPENDYMOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MEDULLOBLASTOMA; MENINGIOMA; MICROTUBULE-ASSOCIATED PROTEINS; NERVOUS SYSTEM NEOPLASMS; NEUROBLASTOMA; TUMOR SUPPRESSOR PROTEINS;

EID: 0033515702     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00171-8     Document Type: Article

References (20)

1. Catzavelos C., Bhattacharya N., Ung Y.C., Wilson J.A., Roncari L., Sandhu C., Shaw P., Yeger H., Morava-Protzner I., Kapusta L., Franssen E., Pritchard K.I., Slingerland J.M. Decreased levels of the cell cycle inhibitor p27kip1 protein: prognostic implications in primary breast cancer. Nat. Med. 3:1997;227-230.
2. Durand B., Fero M.L., Roberts J.M., Raff M.C. p27kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation. Curr. Biol. 8:1998;431-440.
3. Erlanson M., Portin C., Linderholm B., Lindh J., Roos G., Landberg G. Expression of cyclin E and the cyclin-dependent kinase inhibitor p27 in malignant lymphomas-prognostic implications. Blood. 92:1998;770-777.
4. Fredersdorf S., Burns J., Milne A.M., Packham G., Fallis L., Gillett C.E., Royds J.A., Peston D., Hall P.A., Hanby A.M., Barnes D.M., Shousha S., O'Hare M.J., Lu X. High level expression of p27kip1 and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27kip1 and degree of malignancy in human breast and colorectal cancers. Proc. Natl. Acad. Sci. USA. 94:1997;6380-6385.
5. Katayose Y., Kim M., Rakkar A.N.S., Zhuangwu L., Coean K.H., Seth P. Promoting apoptosis: a novel activity associated with the cicling-dependent kinase inhibitor p27. Cancer Res. 57:1997;5441-5445.
6. Katsetos C.D., Herman M.M., Frankfurter A., Gass P., Collins V.P., Walker C.C., Rosemberg S., Barnard R.O., Rubinstein L. Cerebellar desmoplastic medulloblastoma. A further immunohistochemical characterization of the reticulin-free pale islands. Arch. Pathol. Lab. Med. 13:1989;1019-1029.
7. 4. Nature. 227:1970;680-685.
8. Lloyd R.V., Jin L., Qian X., Kulig E. Aberrant p27 kip1 expression in endocrine and other tumors. Am. J. Pathol. 150:1997;401-407.
9. Loda M., Cukor B., Tam S.W., Lavin P., Fiorentino M., Draetta G.F., Jessup J.M., Pagano M. Increased proteasome-dependent degradation of cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat. Med. 3:1997;231-234.
10. Maraziotis T., Perentes E., Karamitopoulou E., Nakagaua Y., Gessaga E.C., Probst A., Frankfurter A. Neuron-associated class III β-tubulin isotype, retinal S-antigen, synaptophysin and glial fibrillary acidic protein in human medulloblastomas. A clinicopathological analysis of 36 cases. Acta Neuropathol. 84:1992;355-363.
11. Mori M., Mimori K., Shirashi T., Tanaka S., Ueo H., Sugimaki K., Akiyoshi T. p27 expression and gastric carcinoma. Nat. Med. 3:1997;593.
12. Pagano M., Tam S.W., Theodoras A.M., Beer-Romero P., Sal G.D., Chau V., Yew P.R., Draetta G.F., Rolfe M. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent inhibitor p27. Science. 269:1995;682-685.
13. Piva R., Cavalla P., Bortolotto S., Cordera S., Richiardi P., Schiffer D. p27/kip1 expression in human astrocytic gliomas. Neurosci. Lett. 234:1997;127-130.
14. Porter, P.L., Malone, K.E., Heagerty, P.J., Alexander, G.M., Gatti, L.A., Firpo, E., Daling, J.R. and Roberts J.M., Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients, Nat. Med., 3 (1997) 222-225.
15. Schiffer D., Cavalla P., Di Sapio A., Giordana M.T., Mauro A. Tumor cell proliferation and apoptosis in medulloblastoma. Acta Neuropathol. 87:1993;362-370.
16. Sherr C.J. Cancer cell cycles. Science. 274:1996;1672-1677.
17. Soos T.J., Kiyokawa H., Yan J.S., Rubin M.S., Giordano A., De Blasio A., Bottega S., Wong B., Mendelsohn J., Koff A. Formation of p27-CDK complexes during the human mitotic cell cycle. Cell Growth Differ. 7:1996;135-146.
18. Tan P., Cady B., Wanner M., Worland P., Cukor B., Magi-Galluzzi C., Lavin P., Draetta G., Pagano M., Loda M. The cell cycle inhibitor p27 is an independent prognostic marker in small (T1 ab) invasive breast carcinomas. Cancer Res. 57:1997;1259-1263.
19. Tsihlias J., Kapusta L.R., DeBoer G., Morava-Protzner I., Zbieranowski I., Bhattacharya N., Catzavelos G.C., Klotz L.H., Slingerland J.M. Loss of cyclin-dependent kinase inhibitor p27/kip1 is a novel prognostic factor in localized human prostate adenocarcinoma. Cancer Res. 58:1998;542-548.
20. Yang R.M., Naitoh J., Murphy M.J., Wang H.J., Philipson J., De Kernion J.B., Loda M., Reiter R.E. Low p27 expression predicts poor disease-free survival in patients with prostate cancer. J. Urol. 159:1988;941-945.