α-Adrenergic blockade improves recovery of myocardial perfusion and function after coronary stenting in patients with acute myocardial infarction

Circulation

Volumn 99, Issue 4, 1999, Pages 482-490

  Gregorini, Luisa ^c   Marco, Jean ^a   Kozàkovà, Michaela ^b   Palombo, Carlo ^b   Anguissola, Gian Battista ^d   Marco, Isabelle ^a   Bernies, Monique ^a   Cassagneau, Bernard ^a   Distante, Alessandro ^b   Bossi, Irene M ^a   Fajadet, Jean ^a   Heusch, Gerd ^d  

^a CLINIQUE PASTEUR   (France)

^b INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d NONE

Author keywords

Adrenergic; Alpha; Autonomic; Myocardial infarction; Nervous system; Receptors; Regional blood flow; Vasoconstriction

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; FIBRINOLYTIC AGENT; ISOSORBIDE DINITRATE; NITRIC OXIDE DONOR; PHENTOLAMINE; PHENTOLAMINE MESYLATE; TICLOPIDINE; URAPIDIL;

ACUTE HEART INFARCTION; ADULT; AGED; ALPHA ADRENERGIC RECEPTOR BLOCKING; ANGIOCARDIOGRAPHY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY OBSTRUCTION; CORONARY STENT; FEMALE; FIBRINOLYTIC THERAPY; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE PERFUSION; HUMAN; INTRACORONARY INFUSION; INTRAVENOUS DRUG ADMINISTRATION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; TRANSLUMINAL CORONARY ANGIOPLASTY;

EID: 0033514319     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.99.4.482     Document Type: Article

References (56)

1. Passamani E, on behalf of the TIMI study group. The Thrombolysis In Myocardial Infarction (TIMI) trial. N Engl J Med. 1985;312:932-936.
2. Chesebro JH, Knatterud G, Roberts R, Borer J, Cohen LS, Dalen J, Dodge HT, Francis CK, Hills D, Ludbrook P, Markis JE, Mueller H, Passamani ER, Powers ER, Rao AK, Robertson T, Ross A, Ryan TJ, Sobel BE, Willerson J, Williams DO, Zaret BL, Braunwald E. Thrombolysis in Myocardial Infarction (TIMI) trial, phase I: a comparison between intravenous tissue plasminogen activator and intravenous streptokinase: clinical findings through hospital discharge. Circulation. 1987;76: 142-154.
3. White HD, Norris RM, Brown MA, Takayama M, Maslowski A, Bass NM, Ormiston JA, Withlock T. Effect of intravenous streptokinase on left ventricular function and early survival after acute myocardial infarction. N Engl J Med. 1987;317:850-855.
4. Van de Werf F. Discrepancies between the effect of coronary reperfusion on survival and left ventricular function. Lancet. 1989;1:1367-1369.
5. Jeremy RW, Links JM, Becker LC. Progressive failure of coronary flow during reperfusion of myocardial infarction: documentation of the no reflow phenomenon with positron emission tomography. J Am Coll Cardiol 1990;16:695-704.
6. Harrison K, Califf RM, Woodlief LH, Kereiakes D, George BS, Stack RS, Ellis SG, Lee KL, O'Neill W, Topol EJ, and the TAMI Study Group. Systolic left ventricular function after reperfusion therapy for acute myocardial infarction: an analysis of determinants of improvement. Circulation. 1993;87:1531-1541.
7. Maes A, Van de Werf F, Nuyts J, Bormans G, Desmet W, Mortelmans L. Impaired myocardial tissue perfusion early after successful thrombolysis: impact on myocardial flow, metabolism, and function at late follow-up. Circulation. 1995;92:2072-2078.
8. Ito H, Okamura A, Iwakura K, Masuyama T, Hori M, Takiuchi S, Negoro S, Nakatsuchi Y, Taniyama Y, Higashino Y, Fujii K, Minamino T. Myocardial perfusion patterns related to thrombolysis in myocardial infarction perfusion grades after coronary angioplasty with acute anterior wall myocardial infarction. Circulation. 1996;93:1993-1999.
9. Lincoff AM, Topol EJ. Illusion of reperfusion: does anyone achieve optimal reperfusion during acute myocardial infarction? Circulation. 1993;88:1361-1374.
10. Heyndrickx GR, Millard RW, McRitchie RJ, Maroko PR, Vatner SF. Regional myocardial function and electrophysiological alterations after brief coronary occlusion in conscious dogs. J Clin Invest. 1975;56: 978-985.
11. Braunwald E, Kloner RA. The stunned myocardium: prolonged post-ischemic ventricular dysfunction. Circulation. 1982;66:1146-1149.
12. Bolli R. Myocardial "stunning." Circulation. 1992;86:1671-1691.
13. TIMI Research Group. Immediate vs delayed catheterization and angioplasty following thrombolytic therapy for acute myocardial infarction: TIMI IIA results. JAMA. 1988;260:2849-2858.
14. Simoons ML, Betriu A, Col J, von Essen R, Lubsen J, Michel PL, Rutsch W, Schmidt W, Thery C, Vahanian A, Willems GM, Arnold AER, De Bono DP, Dougherty FC, Lambertz H, Meier B, Raynaud P, Sanz GA, Uebis R, Van de Werf F, Wood D, Verstraete M, for the European Cooperative Study Group for Recombinant Tissue-Type Plasminogen Activator (rTPA). Thrombolysis with tissue plasminogen activator in acute myocardial infarction: no additional benefit from immediate percutaneous coronary angioplasty. Lancet. 1988;1:197-202.
15. The Multicenter Postinfarction Research Group. Risk stratification and survival after myocardial infarction. N Engl J Med. 1983;309:331-336.
16. Leung WH, Lau CP. Effects of severity of the residual stenosis of the infarct-related coronary artery on left ventricular dilation and function after acute myocardial infarction. J Am Coll Cardiol. 1992;20:307-313.
17. Kim CB, Braunwald E. Potential benefits of late reperfusion of infarcted myocardium: the open artery hypothesis. Circulation. 1993;88: 2426-2436.
18. Gregorini L, Fajadet J, Robert G, Cassagneau B, Bernis M, Marco J. Coronary vasoconstriction following percutaneous transluminal coronary angioplasty is attenuated by antiadrenergic agents. Circulation. 1994;90: 985-997.
19. Gregorini L, Marco J, Palombo C, Kozàkovà M, Anguissola GB, Cassagneau B, Bernies M, Distante A. Fajadet J, Zanchetti A. Post-ischemic LV dysfunction is abolished by alpha-adrenergic blockers. J Am Coll Cardiol. 1998;31:992-1001.
20. Mancini GBJ, Simon SB, Mc Gillem MJ, LeFree MT, Friedman HZ, Vogel RA. Automated quantitative coronary arteriography: morphologic and physiologic validation in vivo of a rapid digital angiographic method. Circulation. 1987;75:452-460.
21. Gibson CM, Cannon CP, Daley WL, Dodge JT, Alexander B, Marble SJ, McCabe CH, Raymond L, Fortin T, Poole WK, Braunwald E, for the TIMI 4 Study Group. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation. 1996;93:879-888.
22. Kremer PF, Cahalan MK, Beaupre PN. Intraoperative myocardial ischemia detected by means of transesophageal echocardiography. Circulation. 1983;68:332-338.
23. Doucette JW, Corl PD, Paine HM, Flynn AE, Goto M, Nassi M, Segal J. Validation of Doppler guide wire for intravascular measurements of coronary artery flow velocity. Circulation. 1992;85:1899-1911.
24. Kozàkovà M, Palombo C, Pratali L, Pitella G, Galetta F, L'Abbate A. Mechanism of coronary flow reserve impairment in human hypertension: an integrated approach by transthoracic and transesophageal echocardiography. Hypertension. 1997;29:551-559.
25. Bartel T, Baumgart D, Müller S, Haude M, Erbel R. Transthoracic Doppler measurements of coronary flow velocity: validation using intracoronary Doppler guide wire. J Am Soc Echocardiogr. 1998;11: 516-101P. Abstract.
26. Gillis RA, Dretchen KL, Namath I, Anastasi N, Souza JD, Hill K, Browne RK, Quest JA. Hypotensive effect of urapidil: CNS site and relative contribution. J Cardiovasc Pharmacol. 1987;9:103-108.
27. 1A receptor in the hypotensive response to urapidil. Am J Cardiol. 1989;64:7D-20D.
28. Bland MJ, Altman DG. Statistical method for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307-309.
29. Tesfamariam B, Cohen RA. Inhibition of adrenergic vasoconstriction by endothelial cell shear stress. Circ Res. 1988;63:720-725.
30. Zanzinger J, Czachurski J, Seller H. Inhibition of sympathetic vasoconstriction is a major principle of vasodilatation by nitric oxide in vivo. Circ Res. 1994;75:1073-1077.
31. Wilson RF, Lesser JR, Laxon DD, White SW. Intense microvascular constriction after angioplasty of acute thrombotic coronary arterial lesions. Lancet. 1989;1:807-811.
32. Felled H, Lichstein E, Schachter J, Shani J. Early and late angiographic findings of the "no-reflow" phenomenon following direct angioplasty as primary treatment of anterior myocardial infarction. Am Heart J. 1992; 123:782-785.
33. Piana RN, Paik GY, Moscucci M, Cohen DJ, Gibson M, Kugelmass AD, Carrozza JP Jr, Kuntz RE, Baim DS. Incidence and treatment of "no-reflow" after percutaneous coronary intervention. Circulation. 1994;89: 2514-2518.
34. 1-adrenoceptor blockade on resting and hyperemic myocardial blood flow in normal humans. Am J Physiol. 1996;271:H1302-H1306.
35. 1-adrenergic blockade in patients with coronary artery disease. J Am Coll Cardiol. 1985;5:840-846.
36. Kramer CM, Rogers WJ, Theobald TM, Power TP, Pertuolo S, Reichek N. Remote noninfarcted region dysfunction soon after first anterior myocardial infarction. Circulation. 1996;94:660-666.
37. Kern MJ, Moore JA, Aguirre FV, Bach RG, Caracciolo EA, Wolford T, Khoury AF, Mechem C, Donohue TJ. Determination of angiographic (TIMI grade) blood flow by intracoronary Doppler flow velocity during acute myocardial infarction. Circulation. 1996;94:1545-1552.
38. Goel M, Rizzo M, McLean C, Ryan K, Dotani I, Vatner R, Marble S, Dodge T, Daley W, Gibson M. Non culprit artery blood flow in acute coronary syndromes is related to culprit artery blood flow: a RESTORE substudy. J Am Coll Cardiol. 1997;30:13A. Abstract.
39. Kelley M, Ryan K, McLean C, Sparano A, Moynihan J, Rizzo M, Marble S, Daley W, Dodge T, Gibson M, for the TIMI study group. Non-culprit artery flow improves over time when flow improves in associated culprit artery. J Am Coll Cardiol. 1998;31:371A. Abstract.
40. Theroux P, Franklin D, Ross J Jr, Kemper WS. Regional myocardial function during acute coronary artery occlusion and its modification by pharmacologic agents in the dog. Circ Res. 1974;35:896-908.
41. Pagani M, Vatner S, Baig H, Braunwald E. Initial myocardial adjustment to brief periods of ischemia and reperfusion in conscious dog. Circ Res. 1978;43:83-92.
42. Nabel EG, Ganz P, Gordon JB, Alexander RW, Selwyn AP. Dilation of normal and constriction of atherosclerotic coronary arteries caused by cold pressor test. Circulation. 1988;77:43-52.
43. Kern MJ, Dupouy P, Drury JH, Aguirre FV, Aptecar E, Bach RG, Caracciolo EA, Danohue TJ, Dubois Rande J-L, Geschwind HJ, Mechem CJ, Kane G, Teiger E, Wolford TL. Role of coronary artery lumen enlargement in improving coronary blood flow after balloon angioplasty and stenting: a combined intravascular ultrasound Doppler flow and imaging study. J Am Coll Cardiol. 1997;29:1520-1527.
44. Malliani A, Schwartz PJ, Zanchetti A. A sympathetic reflex elicited by experimental coronary occlusion. Am J Physiol. 1969;217:703-709.
45. Brown AM, Malliani A. Spinal sympathetic reflexes initiated by coronary receptors. J Physiol (Lond). 1971;212:685-705.
46. Heusch G, Deussen A, Thämer V. Cardiac sympathetic nerve activity and progressive vasoconstriction distal to coronary stenoses: feed-back aggravation of myocardial ischemia. J Auton Nerv Syst. 1985;13:311-326.
47. Heusch G. α-Adrenergic mechanisms in myocardial ischemia. Circulation. 1990;81:1-13.
48. 2-adrenergic constriction in the coronary microcirculation. Circulation. 1993;87:1264-1274.
49. Kern MJ, Deligonul U, Vandormael M, Labovitz A, Gudipati CV, Gabliani G, Bodet J, Shah Y, Kennedy HL. Impaired coronary vasodilator reserve in the immediate post coronary angioplasty period: analysis of coronary artery flow velocity indexes and regional cardiac venous efflux. J Am Coll Cardiol. 1989;13:860-872.
50. Uren NG, Crake T, Lefroy D, de Silva R, Davies GJ, Maseri A. Delayed recovery of coronary resistive vessel function after coronary angioplasty. J Am Coll Cardiol. 1993;21:612-621.
51. 2 and serotonin mediate coronary blood flow reductions in unsedated dogs. Am J Physiol. 1989;257:H873-H882.
52. Golino P, Piscione F, Willerson JT, Cappelli-Bigazzi M, Focaccio A, Villari B, Indolfi C, Russolillo E, Condorelli M, Chiariello M. Divergent effects of serotonin on coronary artery dimensions and blood flow in patients with coronary atherosclerosis and control patients. N Engl J Med. 1991;324:641-648.
53. Gregorini L, Marco J, Fajadet J, Bernies M, Cassagneau B, Brunel P, Bossi IM, Mannucci PM. Ticlopidine and aspirin pretreatment reduces coagulation and platelet activation during coronary dilatation procedure. J Am Coll Cardiol. 1997;29:13-20.
54. 2-adrenoreceptors primarily responsible for inducing human platelet aggregation. Nature. 1979;277:659-661.
55. Theroux P, Ross J Jr, Franklin D, Kemper WS, Sasayama S. Regional myocardial function in the conscious dog during acute coronary occlusion and responses to morphine, propranolol, nitroglycerin and lidocaine. Circ Res. 1974;35:896-908.
56. Carrozza JP, Baim DS. Keeping the open artery open: is stenting the answer? Circulation. 1997;96:2762-2764.