Clinicopathologic and prognostic significance of the expression of mucins, simple mucin antigens and histo-blood group antigens in papillary thyroid carcinoma

Endocrine Pathology

Volumn 10, Issue 4, 1999, Pages 305-313

  Alves, Pedro ^a   Soares, Paula ^a   Rossi, Simone ^a,b   Fonseca, Elsa ^a,c   Sobrinho Simões, Manuel ^a,c  

^a UNIVERSITY OF PORTO   (Portugal)

^b University of Porto Alegre   (Brazil)

^c Inst of Pharmacol and Therapeutics   (Portugal)

Author keywords

Histo blood group antigens; Mucins; Papillary thyroid carcinoma; Prognosis; Simple mucin antigens

Indexed keywords

BLOOD GROUP ANTIGEN; MONOCLONAL ANTIBODY; MUCIN;

ADULT; ANTIBODY SPECIFICITY; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PAPILLARY CARCINOMA; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; THYROID CARCINOMA; THYROID PAPILLARY CARCINOMA;

EID: 0033509779     PISSN: 10463976     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02739773     Document Type: Article

References (33)

1. 1. Longenecker BM Introduction: Glycosylation changes associated to malignancy. Sem Cancer Biol 2:355-356, 1991.
2. 2. Hakomory S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv Cancer Res 52:257-331, 1992.
3. 3. Ho SB, Niehans GA, Lyftogt C, Yan PS, Cherwitz DL, Gum ET, Dahiya R, Kim YS. Heterogeneity of mucin gene expression in normal and neoplastic tissues. Cancer Res 53:641-651, 1993.
4. 4. Schmitt FC, Figueiredo P, Lacerda M. Simple mucin-rype carbohydrate antigens (T, sialosyl-T, Tn and sialosyl-Tn) in breast carcinogenesis. Virchows Arch 427:251-258, 1995.
5. 5. Soares R, Marinho A, Schmitt F. Expression of sialyl-Tn in breast cancer. Correlation with porgnostic parameters. Pathol Res Pract 192:1181-1186, 1996.
6. 6. Narita T, Funahashi H, Satoh Y, Watanabe T, Sakamoto J, Takagi H. Association of expression of blood group-related carbohydrate antigens with prognosis in breat cancer. Cancer 71:3044-3053, 1993.
7. 7. Cho SH, Sahin A, Hortobagyi GN, Hittelman WN, Dhingra K. Sialyl-Tn antigen expression occurs early during human mammary carcinogenesis and is associated with high nuclear grade and aneuploidy. Cancer Res 54:6302-6305, 1994.
8. 8. Mayer B, Funke I, Johnson JP. High expression of a Lewis (x)-related epitope in gastric carcinomas indicates metastatic potential and poor prognosis. Gastroenterology 111:1433-1446, 1996.
9. 9. Victorzon M, Nordling S, Nilson O, Roberts PJ, Haglund C. Sialyl Tn antigen is an independent predictor of outcome in patients with gastric cancer. Int J Cancer 65:295-300, 1996.
10. 10. Werther JL, Tatematsu M, Klein R, Kurihara M, Kumagai K, Llorens P, Guidugli Neto J, Bodian C, Pertsemlidis D, Yamachika T, Kirou T, Itzkowitz S. Sialosyl-Tn antigen as a marker of gastric cancer progression: an international study. Int J Cancer 69:193-199, 1996.
11. 11. Carneiro F, Amado M, David L, Clausen H, Sobrinho-Simões M. Glycosylation features of gastric carcinoma initiation and progression. A review with emphasis on simple mucin-type carbohydrates and histo-blood group antigens of the Lewis system. Euro J Cancer Prev. 3 (supl 2):29-46, 1994
12. 12. Singhal AK, Orntoft TF, Nudelman E, Nance S, Schibig L, Stroud MR, Clausen H, Hakomori S. Profiles of Lewisx-containing glycoproteins and glycolipids in sera of patients with adenocarcinoma. Cancer Res 50:1375-1380, 1990.
13. 13. Ghazizadeh M, Ogawa H, Sasaki Y, Araki T, Arihara k. Mucin carbohydrate antigens (T, Tn and sialyl-Tn) in human ovarian carcinomas: relationship with histopathology and prognosis. Hum Pathol 28:960-966, 1997.
14. 14. Jorsensen T, Berner A, Kaalhus O, Tveter KJ, Danielsen HE, Bryne M. Up-regulation of the oligosaccharide sialyl LewisX: a new prognostic parameter in metastatic prostate cancer. Cancer Res 55:1817-1819, 1995.
15. 15. Fonseca E, Soares P, Rossi S, Sobrinho-Simoes M. Prognostic factors in thyroid carcinomas. Verh Dtsch Ges Pathol 81:82-96, 1997.
16. 16. Gendler SJ, Spicer AP, Lalani EN, Duhig T, Peat N, Burchell J, Pemberto L, Boshell M and Taylor-Papadimitrou. Structure and biology of a carcinoma-associated mucin, MUC1. Am Rev Respir Dis 144:S42-S47, 1991.
17. 17. Damiani S, Fratamico F. Lapertosa G, Dina R and Eusebi V. Alcian Blue and epithelial membrane antigen are useful markers in differentiating benign from malignat papillae in thyroid lesions. Virchows Archiv A Pathol Anat 419:131-135, 1991.
18. 18. Yamamoto Y, Izumi K, Otsuka H. An immunohistochemical study of epithelial membrane antigen, cytokeratin, and vimentin in papillary thyroid carcinoma. Recognition of lethal and favorable prognostic types. Cancer 70:2326-2333, 1992.
19. 19. Ostrowski ML, Merino MJ . Tall cell variant of papillary thyroid carcinoma: a reassessment and immunohistochemical study with comparison to the usual type of papillary carcinoma of the thyroid. Am J Surg Pathol, 20:964-74, 1996.
20. 20. Bryne M, Dabelsten E and Nesland JM. The glycosylation pattern in follicular and papillary thyroid carcinomas. Glycosylation and disease 1:119-125, 1995.
21. 21. Fonseca E, Castanhas S, Sobrinho-Simões M. Expression of simple mucin type antigens and Lewis type 1 and type 2 chain antigens in the thyroid gland: an Immunohistochemical study of normal thyroid tissues, benign lesions, and malignant tumors. Endocrine Pathol 7:291-301, 1996.
22. 22. Fonseca E, Sobrinho-Simões M. Expression of Lewis antigens in papillary carcinoma of the thyroid gland. Virchows Arch 432:483, 1998.
23. 23. Hedinger C, Williams E, Sobin L. Histological typing of thyroid tumors. 2nd ed. WHO International histological classification of tumors. Springer-Verlag , Berlin, 1988.
24. 24. LiVolsi V. Surgical pathology of the thyroid. WB Saunders, Philadelphia, 1990.
25. 25. Rosai J. Thyroid gland. In: Ackerman's Surgical Pathology. 8th ed. Mosby, 1995:493-567.
26. 26. Sanders LE, Cady B. Differentiated thyroid cancer: reexamination of risk groups and outcome of treatment. Arch Surg 133:419-425, 1998.
27. 27. Cady B, Rossi R. An expanded view of risk-group definition in differentiated thyroid carcinoma. Surgery 104:947-953, 1988.
28. 28. Langle F, Soliman T, Neuhold N, Widhalm G, Niederle B, Roka S, Kaserer K, Blauensteiner W, Dam K, Clodi M, et al. CD15 (LeuM1) immunoreactivity: prognostic factor for sporadic and hereditary medullary thyroid cancer? Study Group on Multiple Endocrine Neoplasia of Austria. World J Surg 18:583-587, 1994.
29. 29. Neuhold N, Langle F, Gnant M, Hollenstein U, Niederle B. Relationship of CD15 immunoreactiviry and prognosis in sporadic medullary thyroid carcinoma. J Cancer Res Clin Oncol 118:629-634, 1992.
30. 30. Schröder S, Schwarz W, Rehpenning W, Loning T, Bocker W. Prognostic significance of Leu-M1 immunostaining in papillary carcinomas of the thyroid gland. Virchows Arch A Pathol Anat Histopathol 411:435-439, 1987.
31. 31. Satoh H, Ishikawa H, Kamma H, Yamashita YT, Takahashi H, Ohtsuka M, Hasegawa S. Serum sialyl lewis X-i antigen levels in non-small cell lung cancer: correlation with distant metastasis and survival. Clin Cancer Res 3:495-499, 1997.
32. 32. Amado M, Carneiro F, Seixas M, Clausen H, Sobrinho-Simoes M. Dimeric sialyl-Le(x) expression in gastric carcinoma correlates with venous invasion and poor outcome. Gastroenterology 114:462-470, 1998.
33. 33. Erhard H, Rietveld FB, Brocker EB, de Waal RM, Ruiter DJ. Phenotype of normal cutaneous microvasculature. Immunoelectron microscopic observations with emphasis on the differences between blood vessels and lymphatics. J Invest Dermatol 106:135-140, 1996.