Control of apoptosis in hematopoietic cells by the Bcl-2 family of proteins

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 64, Issue , 1999, Pages 351-358

  Adams, J M ^a   Huang, D C S ^a   Puthalakath, H ^a   Bouillet, P ^a   Vairo, G ^a   Moriishi, K ^a   Hausmann, G ^a   O'Reilly, L ^a   Newton, K ^a   Ogilvy, S ^a   Bath, M L ^a   Print, G G ^a   Harris, A W ^a   Strasser, A ^a   Cory, S ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; BH3 PROTEIN; BIM PROTEIN; DEATH RECEPTOR; IMMUNOGLOBULIN G; PROTEIN BCL XL; PROTEIN P130; PROTEIN P27; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F4;

ANIMAL CELL; APOPTOSIS; CELL CYCLE; CELL FUNCTION; CELL LINEAGE; CELL SURVIVAL; CONFERENCE PAPER; ENZYME ACTIVATION; GENE OVEREXPRESSION; HEMATOPOIETIC CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; LEUKOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CELL KILLING; GENE TARGETING; LYMPHADENOPATHY; PRE T LYMPHOCYTE; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPERMATOGENESIS;

ANIMALIA;

EID: 0033505949     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.1999.64.351     Document Type: Conference Paper

References (13)

1. Adams J.M. and Cory S. 1998. The Bcl-2 protein family: Arbiters of cell survival. Science 281: 1322.
2. Adams J.M., Harris A.W., Strasser A., Ogilvy S., and Cory S. 1999. Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector. Oncogens 18: 5268.
3. Bouillet P., Metcalf D., Huang D.C.S., Tarlinton D.M., Kay T.W.H., Kóntgen F., Adams J.M., and Strasser A. 1999. Bcl-2 family member Bim required for some apoptotic pathways, leukocyte homeostasis, and to preclude autoimmunity. Science 286: 1735.
4. Brady H.J.M., Gil-Gómez G., Kirberg J., and Berns A.J.M. 1996. Baxα perturbs T cell development and affects cell cycle entry of T cells. EMBO J. 15: 6991.
5. Cecconi F., Alvarez-Bolado G., Meyer B.I., Roth K.A., and Gruss P. 1998. Apaf-1 (CED-4 homologue) regulates programmed cell death in mammalian development. Cell 94: 727.
6. Chao D.T. and Korsmeyer S.J. 1998. BCL-2 family: Regulators of cell death. Anna. Rev. Immunol. 16: 395.
7. Conradt B. and Horvitz H.R. 1998. The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9. Cell 93: 519.
8. Cory S. 1995. Regulation of lymphocyte survival by the BCL-2 gene family. Annu. Rev. Immunol. 13: 513.
9. Cory S., Vaux D.L., Strasser A., Harris A.W., and Adams J.M. 1999. Insights from Bcl-2 and Myc: Malignancy involves abrogation of apoptosis as well as sustained proliferation. Cancer Res. 59: 1685s.
10. Domen J., Gandy K.L., and Weissman I.L. 1998. Systemic over-expression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood 91: 2272.
11. Dyson N. 1998. The regulation of E2F by pRB-family proteins. Genes Dev. 12: 2245.
12. Ellis H.M. and Horvitz H.R. 1986. Genetic control of programmed cell death in the nematode C. elegans. Cell 44: 817.
13. Fang G., Chang B.S., Kim C.N., Perkins C., Thompson C.B., and Bhalla K.N. 1998. "Loop" domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis. Cancer Res. 58: 3202.