Phage display of cDNA repertoires: The pVI display system and its applications for the selection of immunogenic ligands

Journal of Immunological Methods

Volumn 231, Issue 1-2, 1999, Pages 39-51

  Hufton, Simon E ^a,c   Moerkerk, Peter T ^a   Meulemans, Els V ^a   De Bruïne, Adriaan ^b   Arends, Jan Willem ^a,b   Hoogenboom, Hennie R ^a,c  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Target Quest BV   (Netherlands)

Author keywords

cDNA display; Filamentous phage; pVI

Indexed keywords

ALKALINE PHOSPHATASE; BETA 2 MICROGLOBULIN; COAT PROTEIN; COMPLEMENTARY DNA; IMMUNOGLOBULIN G; LIGAND; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY;

ARTICLE; AUTOIMMUNE DISEASE; BACTERIAL INFECTION; BACTERIOPHAGE; CANCER; DNA LIBRARY; ESCHERICHIA COLI; IMMUNOGENICITY; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN DOMAIN; VIRUS INFECTION;

ALKALINE PHOSPHATASE; AMINO ACID SEQUENCE; BASE SEQUENCE; CAPSID; CAPSID PROTEINS; CYCLIN-DEPENDENT KINASES; DNA, COMPLEMENTARY; GENETIC VECTORS; HUMANS; IMMUNOGLOBULIN G; LIGANDS; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0033499631     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(99)00139-8     Document Type: Article

References (48)

1. Beekwilder, J., Rakonjac, J., Jongsma, M., Bosch, D., 1999. A phagemid vector using the E. coli phage shock promoter facilitates phage display of toxic proteins. Gene 228, 23.
2. Boder, E.T., Wittrup, K.D., 1997. Yeast surface display for screening combinatorial polypeptide libraries. Nat. Biotechnol. 15, 553.
3. Boublik, Y., Di Bonito, P., Jones, I.M., 1995. Eukaryotic virus display: engineering the major surface glycoprotein of the Autographa californica nuclear polyhedrosis virus (AcNPV) for the presentation of foreign proteins on the virus surface. Biotechnology (N.Y.) 13, 1079.
4. Chiswell, D.J., McCafferty, J., 1992. Phage antibodies: will new/coliclonal' antibodies replace monoconal antibodies. Trends in Biotechnology 10, 80.
5. Clackson, T., Hoogenboom, H.R., Griffiths, A.D., Winter, G., 1991. Making antibody fragments using phage display libraries. Nature 352, 624.
6. Courtney, B.C., Williams, K.C., Schlager, J.J., 1995. A phage display vector with improved stability, applicability and ease of manipulation. Gene 165, 139.
7. Crameri, R., Suter, M., 1993. Display of biologically active proteins on the surface of filamentous phages: a cDNA cloning system for selection of functional gene products linked to the genetic information responsible for their production. Gene 137, 69.
8. Crameri, R., Jaussi, R., Menz, G., Blaser, K., 1994. Display of expression products of cDNA libraries on phage surfaces. A versatile screening system for selective isolation of genes by specific gene-product/ligand interaction. Eur. J. Biochem. 226, 53.
9. Crameri, R., Faith, A., Hemmann, S., Jaussi, R., Ismail, C., Menz, G., Blaser, K., 1996. Humoral and cell-mediated autoimmunity in allergy to Aspergillus fumigatus. J. Exp. Med. 184, 265.
10. de Haard, H., van Neer, N., Reurs, A., Hufton, S.E., Roovers, R.C., Hendrikx, P., Arends, J.W., Hoogenboom, H.R., 1999. A large naive human Fab repertoire that permits the rapid isolation and kinetic analysis of high affinity antibodies. J. Biol. Chem. 274, 18218.
11. Dennis, M.S., Lazarus, R.A., 1994. Kunitz domain inhibitors of tissue factor-factor Vila: I. Potent inhibitors selected from libraries by phage display. J. Biol. Chem. 269, 22129.
12. Dunn, I.S., 1995. Assembly of functional bacteriophage lambda virions incorporating C-terminal peptide or protein fusions with the major tail protein. J. Mol. Biol. 248, 497.
13. Efimov, V.P., Nepluev, I.V., Mesyanzhinov, V.V., 1995. Bacteriophage T4 as a surface display vector. Virus Genes 10, 173.
14. Georgiou, G., Stathopoulos, C., Daugherty, P.S., Nayak, A.R., Iverson, B., Curtiss, R., 1997. Display of heterologous proteins on the surface of microorganisms: from the screening of combinatorial libraries to live recombinant vaccines. Nat. Biotechnol. 15, 29.
15. Gram, H., Marconi, L.A., Barbas, C.F.d., Collet, T.A., Lerner, R.A., Kang, A.S., 1992. In vitro selection and affinity matura-tion of antibodies from a naive combinatorial immunoglobulin library. Proc. Natl. Acad. Sci. U.S.A. 89, 3576.
16. Gram, H., Strittmatter, U., Lorenz, M., Gluck, D., Zenke, G., 1993. Phage display as a rapid gene expression system: production of bioactive cytokine-phage and generation of neutralizing monoclonal antibodies. J. Immunol. Methods 161, 169.
17. Hanes, J., Pluckthun, A., 1997. In vitro selection and evolution of functional proteins by using ribosome display. Proc. Natl. Acad. Sci. U.S.A. 94, 4937.
18. He, M., Taussig, M.J., 1997. Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites. Nucleic Acids Res. 25, 5132.
19. Hufton, S.E., Moerkerk, P., de Brume, A.P., Arends, J.W., Hoogenboom, H.R., 1998. Serological antigen selection of phage displayed colorectal tumor cDNA libraries. Biochem. Soc. Trans. 26.
20. Jacobsson, K., Frykberg, L., 1995. Cloning of ligand-binding domains of bacterial receptors by phage display. Biotechniques 18, 878.
21. Jacobsson, K., Frykberg, L., 1996. Phage display shot-gun cloning of ligand binding domains of prokaryotic receptors approaches 100% correct clones. Biotechniques 20, 1070.
22. Jespers, L., Messens, J.H., De Keyser, A., Eeckhout, D., Van den Brande, J., Gandemans, Y., Lauwereys, M.J., Vlasuk, G.P., Stanssens, P.E., 1995. Surface expression and ligand-based selection of cDNAs fused to filamentous phage gene VI. Bio/Technology 13, 378.
23. Jespers, L.S., De Keyser, A., Stanssens, P.E., 1996. Lambda ZLG6: a phage lambda vector for high-efficiency cloning and surface expression of cDNA libraries on filamentous phage. Gene 173, 179.
24. Jiang, J., Abu-Shilbayeh, L., Rao, V.B., 1997. Display of a PorA peptide from Neisseria meningitidis on the bacteriophage T4 capsid surface. Infect. Immun. 65, 4770.
25. Krebber, A., Burmester, J., Pluckthun, A., 1996. Inclusion of an upstream transcriptional terminator in phage display vectors abolishes background expression of toxic fusions with coat protein g3p. Gene 178, 71.
26. Kuwabara, I., Maruyama, H., Mikawa, Y.G., Zuberi, R.I., Liu, F.T., Maruyama, I.N., 1997. Efficient epitope mapping by bacteriophage lambda surface display. Nat. Biotechnol. 15, 74.
27. Laemmli, U.K., 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680.
28. Lutz, R., Bujard, H., 1997. Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/Il-I2 regulatory elements. Nucleic Acids Res. 25, 1203.
29. Makowski, L., 1992. Terminating a macromolecular helix. Structural model for the minor proteins of bacteriophage M13. J. Mol. Biol. 228, 885.
30. Markland, W., Ley, A.C., Lee, S.W., Ladner, R.C., 1996. Iterative optimization of high-affinity proteases inhibitors using phage display: 1. Plasmin. Biochemistry 35, 8045.
31. Marks, J.D., Hoogenboom, H.R., Bonnert, T.P., McCafferty, J., Griffiths, A.D., Winter, G., 1991. By-passing immunization: human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222, 581.
32. Maruyama, I.N., Maruyama, H.I., Brenner, S., 1994. Lambda foo: a lambda phage vector for the expression of foreign proteins. Proc. Natl. Acad. Sci. U.S.A. 91, 8273.
33. Mattheakis, L.C., Bhatt, R.R., Dower, W.J., 1994. An in vitro polysome display system for identifying ligands from very large peptide libraries. Proc. Natl. Acad. Sci. U.S.A. 91, 9022.
34. McCafferty, J., Griffiths, A.D., Winter, G., Chiswell, D.J., 1990. Phage antibodies: filamentous phage displaying antibody variable domains. Nature 348, 552.
35. McCafferty, J., Jackson, R.H., Chiswell, D.J., 1991. Phage-enzymes: expression and affinity chromatography of functional alkaline phosphatase on the surface of bacteriophage. Protein Eng. 4, 286.
36. McConnell, S.J., Hoess, R.H., 1995. Tendamistat as a scaffold for conformationally constrained phage peptide libraries. J. Mol. Biol. 250, 460.
37. Mikawa, Y.G., Maruyama, I.N., Brenner, S., 1996. Surface display of proteins on bacteriophage lambda heads. J. Mol. Biol. 262, 21.
38. Palzkill, T., Huang, W., Weinstock, G.M., 1998. Mapping protein-ligand interactions using whole genome phage display libraries. Gene 221, 79.
39. Ren, Z.J., Lewis, G.K., Wingfield, P.T., Locke, E.G., Steven, A.C., Black, L.W., 1996. Phage display of intact domains at high copy number: a system based on SOC, the small outer capsid protein of bacteriophage T4. Protein Sci. 5, 1833.
40. Russell, S.J., Hawkins, R.E., Winter, G., 1993. Retroviral vectors displaying functional antibody fragments. Nucleic Acids Res. 21, 1081.
41. Santini, C., Brennan, D., Mennuni, C., Hoess, R.H., Nicosia, A., Cortese, R., Luzzago, A., 1998. Efficient display of an HCV cDNA expression library as C-terminal fusion to the capsid protein D of bacteriophage lambda. J. Mol. Biol. 282, 125.
42. Smith, G.P., 1985. Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. Science 228, 1315.
43. Soumillion, P., Jespers, L., Bouchet, M., Marchand, B.J., Winter, G., Fastrez, J., 1994. Selection of beta-lactamase on filamentous bacteriophage by catalytic activity. J. Mol. Biol. 237, 415.
44. Sternberg, N., Hoess, R.H., 1995. Display of peptides and proteins on the surface of bacteriophage lambda. Proc. Natl. Acad. Sci. U.S.A. 92, 1609.
45. Tureci, O., Sahin, U., Pfreundschuh, M., 1997. Serological analysis of human tumor antigens: molecular definition and implications. Mol. Med. Today 3, 342.
46. Vermorken, J.B., Claessen, A.M., van Tinteren, H., Gall, H.E., Ezinga, R., Meijer, S., Scheper, R.J., Meijer, C.J., Bloemena, E., Ransom, J.H., Hanna, M.G. Jr., Pinedo, H.M., 1999. Active specific immunotherapy for stage II and stage III human colon cancer: a randomised trial. Lancet 353, 345.
47. Winter, G., Griffiths, A.D., Hawkins, R.E., Hoogenboom, H.R., 1994. Making antibody by phage display technology. Annu. Rev. Immunol. 12, 433.
48. Wu, H., Yang, W.P., Barbas, C.F. III, 1995. Building zinc fingers by selection: toward a therapeutic application. Proc. Natl. Acad. Sci. U.S.A. 92, 344.