Burn injury with infection alters prostaglandin E2 synthesis and metabolism

Journal of Trauma - Injury, Infection and Critical Care

Volumn 47, Issue 6, 1999, Pages 1052-1059

  Hahn, Elisabeth L ^a   Tai, Hsin Hsiung ^b   He, Like K ^a   Gamelli, Richard L ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Burn injury; Cyclooxygenase; Prostaglandin 15 hydroxydehydrogenase; Prostaglandin E2

Indexed keywords

15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; CYCLOOXYGENASE 2; MESSENGER RNA; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BURN; CONFERENCE PAPER; CONTROLLED STUDY; INFECTION; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN METABOLISM; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RNA ANALYSIS; TRANSCRIPTION REGULATION;

EID: 0033457937     PISSN: 00225282     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005373-199912000-00010     Document Type: Conference Paper

References (36)

1. Curreri PW, Luterman A, Braun DW jr, Shires GT. Burn injury. Analysis of survival and hospitalization time for 937 patients. Ann Surg. 1980;192:472-478.
2. Salkowski CA, Detore D, Franks A, Falk MC, Vogel SN. Pulmonary and hepatic gene expression following cecal ligation and puncture: monophosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and chemokine expression and neutrophil infiltration. Infect Immun. 1998;66:3569-3578.
3. Ondrey FG, Arachidonic acid metabolism: A Primer for head and neck surgeons. Head Neck. 1998;20:334-349.
4. Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, DuBois RN. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell. 1998;93:705-716.
5. 2 production in severely injured patients. Arch Surg 1988;123:293-299.
6. 2 level by antiserum against core lipopolysaccharide in a rabbit model of multiple organ failure. J Trauma. 1996;40:270-277.
7. 2)-dependent suppression of interleukin-2 production in patients with major trauma. J Trauma. 1987;27:837-848.
8. Gamelli RL, He LK, Liu H. Marrow granulocyte-macrophage progenitor cell response to burn injury as a modified by endotoxin and indomethacin. J Trauma. 1994; 37:339-346.
9. Gamelli RL, Herbert JC, Foster RS. Effect of burn injury on granulocyte and macrophage production. J Trauma. 1985; 25:615-619.
10. Gamelli RL, He LK, Liu H. Macrophage suppression of granulocyte and macrophage growth following burn wound infection. J Trauma. 1994;37:888-892.
11. 2 by macrophages isolated after thermal injury and bacterial translocation. Circ Shock. 1994;42:154-162.
12. Gerritsen ME. Physiological and pathophysiological roles of eicosanoids in the microcirculation. Cardiovasc Res. 1996; 32:720-732.
13. Wyllie JH, Piper PJ, Vane JR. Fate of prostaglandins in the lungs. Br J Surg. 1969;56:623.
14. Piper PJ. Release and metabolism of prostaglandins in lung tissue. Pol J Pharm Pharmacol. 1976;26:61-72.
15. Piper PJ, Vane JR, Wyllie JH. Inactivation of prostaglandins by the lungs. Nature. 1970;225:600-604.
16. + -dependent prostaglandin dehydrogenase, carbonyl reductase, and cytochrome P450-dependent prostaglandin omega-hydroxylase. Crit Rev Biochem Mol Biol. 1996;31:101-126.
17. Hahn EL, Clancy KD, Tai HH, Ricken JD, He LK, Gamelli RL. Prostaglandin E2 alterations during sepsis are partially mediated by endotoxin-induced inhibition of prostaglandin 15-hydroxydehydrogenase. J Trauma. 1998; 44:777-781.
18. 2. J Surg Res. 1990;48:523-527.
19. Arias-Negrete S, Keller K, Chadee K. Proinflammatory cytokines regulate cyclooxygenase-2 mRNA expression in human macrophages. Biochem Biophys Res Commun. 1995; 208:582-589.
20. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156-159.
21. Clancy KD, Lorenz K, Hahn E, et al. Down-regulation of tissue specific tumor necrosis factor-α in the liver and lung after burn injury and endotoxemia. J Trauma. 1997;42:169-176.
22. Fourney RM, Miyashi J, Day RS. Northern blotting: efficient RNA staining and transfer. Focus. 1988;10:5-7.
23. +-dependent 15-hydroxyprostaglandin dehydrogenase. Biochim Biophys Acta. 1996;1309:21-24.
24. Moore TA, Standiford TJ. The role of cytokines in bacterial pneumonia: an inflammatory balancing act. Proc Assoc Am Physicians. 1998;110:297-305.
25. Robertson RP. Molecular regulation of prostaglandin synthesis. Implications for endocrine systems. Trends Endoc Metab. 1995;6:293-297.
26. Feng L, Xia Y, Garcia GE. Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-α and lipopolysaccharide. J Clin Invest. 1995;95:1669-1675.
27. Williams CS, DuBois RN. Prostaglandin endoperoxide synthase: why two isoforms? Am J Physiol. 1996;270:G393-G400.
28. Tai HH, Hollander CS. Regulation of prostaglandin metabolism: activation of 15-hydroxyprostaglandin dehydrogenase by chlorpromazine and imipramine related drugs. Biochem Biophys Res Commun. 1976;68:814-820.
29. Liu Y, Tai HH, Inactivation of 15-hydroxyprostaglandin dehydrogenase by acrolein. Biochem Pharmacol 1985; 34:4275-4278.
30. Matsuo M, Ensor CM, Tsai HH. Characterization of the genomic structure and the promoter of the mouse NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene. Biochem Biophys Res Commun. 1997;235:582-586.
31. Blackwell GJ, Flowers RJ, Vane JR, Rapid reduction of prostaglandin 15-hydroxy dehydrogenase activity in rat tissues after treatment with protein synthesis inhibitors. Br J Pharmacol. 1975;55:233-238.
32. Gibb W. The role of prostaglandins in human parturition. Ann Med. 1998;30:235-241.
33. van Meir CA, Matthews SG, Keirse MJ, Ramirez MM, Bocking A, Challis JR. 15-Hydroxyprostaglandin dehydrogenase-implications in preterm labor with and without ascending infection. J Clin Endocrinol Metab. 1997; 82:969-976.
34. Bruckner UB, Pfetsch H, Kinzl L, et al. Prognostic importance of preclinically evaluated inflammatory mediators in polytrauma. Zentralbl Chir. 1999;124:303-310.
35. Chan CC, Boyce S, Brideau C, et al. Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745, 337: a novel nonsteroidal anti-inflammatory agent with ulcerogenic sparing effect in rat and nonhuman primate stomach. J Pharmacol Exp Ther. 1995;274:1531-1537.
36. Shoup M, He LK, Lui H, Shankar R, Gamelli R. Cyclooxygenase-2 inhibitor NS-398 improves survival and restores leukocyte counts in burn infection. J Trauma. 1998; 45:215-220.