Dual role for noradrenergic innervation of lymphoid tissue and arthritic joints in adjuvant-induced arthritis

Brain, Behavior, and Immunity

Volumn 13, Issue 4, 1999, Pages 315-334

  Lorton, Dianne ^a   Lubahn, Cheri ^a   Klein, Nathan ^a   Schaller, Jill ^a   Bellinger, Denise L ^b  

^a SUN HEALTH RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Adjuvant induced arthritis; Autoimmune diseases; Neural immune; Noradrenergic innervation

Indexed keywords

FREUND ADJUVANT; GUANETHIDINE; NEUROTOXIN; OXIDOPAMINE;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENERVATION; DISEASE SEVERITY; HINDLIMB; IMMUNIZATION; LYMPHATIC DRAINAGE; LYMPHOID TISSUE; NERVE ENDING; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; RAT; SYMPATHETIC NERVE; X RAY ANALYSIS;

EID: 0033452482     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1006/brbi.1999.0564     Document Type: Article

References (55)

1. Ackerman N. R., Rooks W. H., Shott L., Genant H., Maloney P., West E. Effects of naprofen on connective tissue changes in the adjuvant arthritic rat. Arthritis Rheum. 22:1979;1365-1374.
2. Agius M. A., Checinski M. E., Richman D. P., Chelmicka-Shorr E. Sympathectomy enhances the severity of experimental autoimmune myasthenia gravis (EAMG). J. Neuroimmunol. 16:1987;11-12.
3. Bellinger D. L., Ackerman K. D., Felten S. Y., Lorton D., Felten D. L. Noradrenergic sympathetic innervation of thymus, spleen, and lymph nodes: Aspects of development, aging and plasticity in neural immune interaction. Hadden J. W., Masek K., Nistico G. Interactions among central nervous system, neuroendocrine and immune systems. 1989;35-66 Pythagora Press, Rome.
4. Brenneman A. M., Moynihan J. A., Grota L. J., Felten D. L., Felten S. Y. Splenic norepinephrine is decreased in MRL-lpr/lpr mice. Brain Behav. Immun. 7:1993;135-143.
5. Chelmicka-Schorr E., Checinski M., Arnason B. G. W. Chemical sympathectomy augments the severity of experimental allergic encephalomyelitis. J. Neuroimmunol. 17:1988;347-350.
6. Chelmicka-Schorr E., Kwasniewski M. N., Thomas B. E., Arnason B. G. W. The β-adrenergic agonist isoproterenol suppresses experimental allergic encephalomyelitis in Lewis rats. J. Neuroimmunol. 25:1989;203-207.
7. Chelmicka-Schorr E., Wollmann R. L., Kwasniewski M. N., Kim D. H., Dupont B. L. The beta 2-adrenergic agonist terbutaline suppresses acute passive transfer experimental autoimmune myasthenia gravis (EAMG). Int. J. Immunopharmacol. 15:1993;19-24.
8. Colpaert F. C., Donnerer J., Lembeck F. Effects of capsaicin on inflammation and on the substance P content of nervous tissue in rats with adjuvant arthritis. Life Sci. 32:1983;1827-1834.
9. de Jong-De Vos Van Steenwijk C. C., Wieling W., Johannes M. J., Harms M. P., Heijnen C. J., Kuis W., Wesseling D. H. Incidence and hemodynamic characteristics of near-fainting in healthy 6- to 16-year old subjects. J. Am. Coll. Cardiol. 25:1994;1615-1621.
10. Felten D. L., Felten S. Y., Bellinger D. L., Lorton D. Noradrenergic and peptidergic innervation of secondary lymphoid organs: role in experimental rheumatoid arthritis. Eur. J. Clin. Invest. 22:1992;37-41.
11. Halata Z., Groth H.-P. Innervation of the synovial membrane of the cat's joint capsule. An ultrastructural study. Cell Tissue Res. 169:1976;415-418.
12. Highton J., Panayi G. S., Sheperd P., Griffin J., Gibson T. Changes in immune function in patients with rheumatoid arthritis following treatment with sodium aurothiomalate. Ann. Rheum. Dis. 40:1981;254-262.
13. Issekutz T. B., Issekutz A. C. T lymphocyte migration to arthritic joints and dermal inflammation in the rat: Differing migration patterns and the involvement of VLA-4. Clin. Immunol. Immunopathol. 61:1991;436-447.
14. Johnson H. M., Russell J. K., Pontzer C. H. Staphylococcal enterotoxin microbial superantigen. FASEB J. 5:1991;2706-2712.
15. Josefsson E., Mansson J.-E., Blennow K., Tarkowski A. Immunomodulating and anti-inflammatory properties of the sympatholytic compound 6-hydroxydopamine. J. Neuroimmunol. 55:1994;161-169.
16. Kalliomaki J., Saariman H. A., Toivanen P. Axon reflex sweating in rheumatoid arthritis. Ann. Rheum. Dis. 22:1963;46-49.
17. Kaplan R., Robinson C. A., Scavulli J. F., Vaughan J. H. Propranolol and the treatment of rheumatoid arthritis. Arthritis Rheum. 23:1980;253-255.
18. Kapusta M. A., Young-Rodenchud M., Kourounakis L. Restoration of diminished splenic responses to PHA and Con-A in adjuvant-induced by Virazole: Possible pathogenetic role of a virus and suppressor cells. J. Rheumatol. 6:1979;507-518.
19. 2-adrenergic agonist terbutaline suppresses experimental allergic neuritis in Lewis rats. J. Neuroimmunol. 51:1994;177-183.
20. Koopman W. J., Schrohenloher R. E. Enhanced in vitro synthesis of IgM rheumatoid factor in rheumatoid arthritis. Arthritis Rheum. 23:1980;985-992.
21. Kourounakis L., Kapusta M. A. Effect of Freund's adjuvant on the mitogenic responses of rat lymphocyte. Ann. Rheum. Dis. 33:1974;185-189.
22. Kruszewska B., Felten S. Y., Moynihan J. A. Alterations in cytokine and antibody production following chemical sympathectomy in two strains of mice. J. Immunol. 155:1995;4613-4620.
23. Langford L. A., Schmidt R. F. Afferent and efferent axons in the medial and posterior articular nerves of the cat. Anat. Rec. 206:1983;71-78.
24. Leden I., Eriksson A., Lilja B., Sturfelt G., Sundkvist G. Autonomic nerve function in rheumatoid arthritis of varying severity. Scand. R. Rheumatol. 12:1983;166-177.
25. Levine J. D., Clark R., Devor M., Helms C., Moskowitz M. A., Basbaum A. I. Intraneuronal substance P contributes to the severity of experimental arthritis. Science. 226:1984;547-549.
26. 2-adrenergic mechanisms in experimental arthritis. Proc. Natl. Acad. Sci. USA. 85:1988;4553-4556.
27. Levine J. D., Collier D. H., Basbaum A. I., Moskowitz M. A., Helms C. A. Hypothesis: The nervous system may contribute to the pathophysiology of rheumatoid arthritis. J. Rheumatol. 12:1985;406-411.
28. Levine J. D., Dardick S. J., Roizen M. F., Helms C., Basbaum A. L. Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis. J. Neurosci. 6:1986a;3423-3429.
29. Levine J. D., Fye K., Heller P., Basbaum A. I., Whiting-O'Keefe Q. Clinical response to regional intravenous guanethidine in patients with rheumatoid arthritis. J. Rheumatol. 13:1986b;1040-1043.
30. Levine J. D., Goetzl E. J., Basbaum A. I. Contribution of the nervous system to the pathophysiology of rheumatoid arthritis and other polyarthritides. Rheumatic Disease Clinics of North America. 13:1991;369-383.
31. Livnat S., Eisen J., Felten D. L., Felten S. Y., Irwin J., Madden K. S., Sundaresan P. J. Behavioral and sympathetic neural modulation of immune function. Dahlstrom A., Belmaker R. M., Sandler M. Progress in catecholamine research, part A: Basic aspects and peripheral mechanisms. 1988;539-546 A. R. Liss, New York.
32. Livnat S., Felten S. Y., Carlson S. L., Bellinger D. L., Felten D. L. Involvement of peripheral and central catecholamine systems in neural-immune interactions. J. Neuroimmunol. 10:1985;5-30.
33. Livnat S., Madden K. S., Felten D. L., Felten S. Y. Regulation of the immune system by sympathetic neural mechanisms. Prog. Neuro-psychopharmacol. Biol. Psychiatr. 11:1987;145-152.
34. Loren I., Bjorklund A., Falck B., Lindvall O. An improved histofluorescence procedure for freeze-dried paraffin-embedded tissue based on combined formaldehyde-glyoxylic acid perfusion with high magnesium content and acid pH. Histochemistry. 49:1976;177-192.
35. Lorton D., Bellinger D. L., Duclos M., Felten S. Y., Felten D. L. Application of 6-hydroxydopamine into the fatpads surrounding the draining lymph nodes exacerbates adjuvant-induced arthritis. J. Neuroimmunol. 64:1996;103-113.
36. Lorton D., Bellinger D. L., Hewitt D., Felten S. Y., Felten D. L. Noradrenergic reinnervation of the rat spleen following chemical sympathectomy with 6-hydroxydopamine: pattern and time course of reinnervation. Brain, Behav. Immun. 4:1990;198-222.
37. Lorton D., Lubahn C., Felten S. Y., Bellinger D. L. Norepinephrine content in primary and secondary lymphoid organs is altered in rats with adjuvant-induced arthritis. Mechan. Ageing Dev. 94:1997;145-163.
38. Madden K. S., Felten S. Y., Felten D. L., Livnat S. Sympathetic neural modulation of the immune system. I. Depression of T cell immunity in vivo and in vitro following chemical sympathectomy. Brain Behav. Immun. 3:1989;72-89.
39. Madden K. S., Livnat S. Catecholaminergic action on immunologic reactivity. Ader R., Felten D. L., Cohen N. Psychoneuroimmunology, 2nd ed., 1991;283-310 Academic Press, New York.
40. Madden K. S., Moynihan J. A., Brenner G. J., Felten S. Y., Felten D. L., Livnat S. Sympathetic nervous system modulation of the immune system. III. Alterations in T and B cell proliferation and differentiation in vitro following chemical sympathectomy. J. Neuroimmunol. 49:1994;77-87.
41. Manning P. T., Powers C. W., Schmidt R. E., Johnson E. M. Jr. Guanethidine-induced destruction of peripheral sympathetic neurons occurs by an immune-mediated mechanism. J. Neurosci. 3:1983;714-724.
42. Miltenburg A. M. M., van laar J. M., de Kuiper R., Kahja M. R., Breedveld F. C. T cells cloned from human rheumatoid synovial membrane functionally represent the Th1 subset. Scand. J. Immunol. 35:1992;603-610.
43. Newbould B. B. Lymphatic drainage and adjuvant induced arthritis in rats. Ann. N.Y. Acad. Sci. 45:1964a;375-383.
44. Newbould B. B. Role of lymph nodes in adjuvant-induced arthritis in rats. Ann. Rheum. Dis. 23:1964b;392-396.
45. Olsen N. J., Jasin H. E. Synthesis of rheumatoid factor in vitro: Implications for the pathogenesis of rheumatoid arthritis. Semin. Arthritis Rheum. 15:1985;146-156.
46. Parish R. S. Nonspecific suppressor function in rheumatoid arthritis. J. Clin. Lab. Immunol. 9:1982;59-64.
47. Pearson C. M., Wood R. D. Studies of arthritis and other lesions induced in rats by injection of mycobacterial adjuvant. VII. Pathologic details of the arthritis and spondylitis. Am. J. Pathol. 42:1963;73-95.
48. Percy J. S., Davis P., Russell A. S. A longitudinal study of in vitro tests for lymphocyte function in RA. Ann. Rheum. Dis. 37:1978;416-420.
49. Perry F., Heller P. H., Kamiya J., Levine J. D. Altered autonomic functions in patients with arthritis or with chronic myofascial pain. Pain. 39:1989;77-84.
50. Quayle A. J., Chomarat P., Miossec P., Kjeldsen-Kragh J., Forre O., Natvig J. B. Rheumatoid inflammatory T-cell clones express mostly Th1 but also Th2 and mixed (Th0-like) cytokine patterns. Scand. J. Immunol. 38:1993;75-82.
51. Ramer-Quinn D. S., Baker R. A., Sanders V. M. Activated T helper 1 and T helper 2 cells differentially express the β-2-adrenergic receptor. J. Immunol. 159:1997;4857-4867.
52. 2-adrenergic receptor by Th1 and Th2 clones: Implications for cytokine production and B cell help. J. Immunol. 158:1997;4200-4210.
53. Vyden J. K., Groseth-Dittrich M. F., Callis G., Lars M. M., Weinberger H. The effect of propranolol on peripheral hemodynamics in rheumatoid arthritis. Arthritis Rheum. 14:1971;420.
54. Wegelires O., Skrifvars B., Andersson L. Rheumatoid arthritis terminating in plasmacytoma. Acta Med. Scand. 187:1970;133-138.
55. Winer B. J. Statistical principles in experimental design. 1971;McGraw-Hill, New York.