Distribution of alleles of the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism in familial spina bifida

American Journal of Medical Genetics

Volumn 87, Issue 5, 1999, Pages 407-412

  Johnson, William G ^a,e   Stenroos, Edward S ^a   Heath, Simon C ^b   Chen, Yanping ^a   Carroll, Regina ^a   McKoy, Vershon V ^a   Chatkupt, Sansnee ^c,d   Lehner, Thomas ^b  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^d UMDNJ New Jersey Medical School   (United States)

^e UBHC   (United States)

Author keywords

Case control study; Folate; Monte Carlo methods; MTHFR C677T polymorphism; Spina bifida; Transmission disequilibrium test

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); DNA;

ALLELE; ARTICLE; BIRTH DEFECT; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; HUMAN; MALE; NEURAL TUBE DEFECT; PEDIGREE ANALYSIS; PRIORITY JOURNAL; RISK FACTOR; SPINA BIFIDA;

ALLELES; CASE-CONTROL STUDIES; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC SCREENING; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MONTE CARLO METHOD; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PEDIGREE; POLYMORPHISM, GENETIC; RISK FACTORS; SPINA BIFIDA CYSTICA;

EID: 0033405863     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19991222)87:5<407::AID-AJMG7>3.0.CO;2-Z     Document Type: Article

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