Signaling events in NMDA receptor-induced apoptosis in cerebrocortical cultures

Annals of the New York Academy of Sciences

Volumn 893, Issue , 1999, Pages 261-264

  Budd, Samantha L ^a   Lipton, Stuart A ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONGKREKIC ACID; CALCIUM ION; CASPASE 3; CYTOCHROME C; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; STAUROSPORINE;

APOPTOSIS; BRAIN CORTEX; CONFERENCE PAPER; DEPOLARIZATION; ENZYME ACTIVATION; ENZYME RELEASE; MITOCHONDRION; NERVE CELL CULTURE; SIGNAL TRANSDUCTION;

EID: 0033401849     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07832.x     Document Type: Conference Paper

References (10)

1. 1. Portera-Cailliau, C. et al. 1995. Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models. J. Neurosci. 15: 3775-3787.
2. 2. Barinaga, M. 1998. Is apoptosis key in Alzheimer's disease? Science 271: 1303-1304.
3. 3. Burke, R.E. & N.G. Kholodilov. 1998. Programmed cell death: does it play a role in Parkinson's disease? Ann. Neurol. 44: S126-S133.
4. 4. Bonfoco, E. et al. 1995. Apoptosis and necrosis: two distinct events induced respectively by mild and intense insults with NMDA or nitric oxide/superoxide in cortical cell cultures. Proc. Natl. Acad. Sci. USA 92: 7162-7166.
5. 5. Budd, S.L. & D.G. Nicholls. 1996. Mitochondria, calcium and acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurochem. 66: 403-411.
6. 6. Kluck, R.M. et al. 1997. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275: 1132-1136.
7. 7. Yang, J. et al. 1997. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275: 1129-1132.
8. 8. Marchetti, P. et al. 1996. Mitochondrial permeability transition is a central coordinating event of apoptosis. J. Exp. Med. 184: 1155-1160.
9. 9. Marchetti, P. et al. 1996. Mitochondrial permeability transition triggers lymphocyte apoptosis. J. Immunol. 157: 4830-4836.
10. 10. Åkerman, K. 1978. Changes in membrane potential during calcium ion influx and efflux across the mitochondrial membrane. Biochim. Biophys. Acta 502: 359-366.