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Volumn 29, Issue 12, 1999, Pages 1614-1625

Identification of isoform-specific T-cell epitopes in the major timothy grass pollen allergen, Phl p 5

Author keywords

Grass group 5 allergens; Major histocompatibility complex; T lymphocytes; T cell epitopes; T cell receptors

Indexed keywords

ALLERGEN; ALLERGEN PHL P 5; CD4 ANTIGEN; EPITOPE; UNCLASSIFIED DRUG;

EID: 0033390324     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.1999.00652.x     Document Type: Article
Times cited : (16)

References (44)
  • 1
    • 0029175839 scopus 로고
    • Allergic rhinitis: An increasing clinical problem
    • 1 Howard PH, Holmberg K. Allergic rhinitis: an increasing clinical problem. Allergy 1995; 50:4-5.
    • (1995) Allergy , vol.50 , pp. 4-5
    • Howard, P.H.1    Holmberg, K.2
  • 3
    • 0025905118 scopus 로고
    • Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production
    • 3 Parronchi P, Macchia DP, Iccinni M et al. Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production. Proc Natl Acad Sci USA 1991; 88:4538.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4538
    • Parronchi, P.1    Macchia, D.P.2    Iccinni, M.3
  • 5
    • 0025963596 scopus 로고
    • Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL4, IL5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects
    • 5 Kay AB, Ying S, Varney V et al. Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL4, IL5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects. J Exp Med 1991; 173:775-8.
    • (1991) J Exp Med , vol.173 , pp. 775-778
    • Kay, A.B.1    Ying, S.2    Varney, V.3
  • 6
    • 0026610142 scopus 로고
    • Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma
    • 6 Robinson D, Hamid QA, Ying S et al. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Eng J Med 1992; 326:298-304.
    • (1992) N Eng J Med , vol.326 , pp. 298-304
    • Robinson, D.1    Hamid, Q.A.2    Ying, S.3
  • 7
    • 0026024576 scopus 로고
    • Accumulation of Th-2-like helper T cells in the conjuctiva of patients with vernal conjunctivitis
    • 7 Maggi E, Biswas P, Del Prete GF et al. Accumulation of Th-2-like Helper T cells in the conjuctiva of patients with vernal conjunctivitis. J Immunol 1991; 146:1169-74.
    • (1991) J Immunol , vol.146 , pp. 1169-1174
    • Maggi, E.1    Biswas, P.2    Del Prete, G.F.3
  • 9
    • 0027177930 scopus 로고
    • T cell epitopes of house dust mite major allergen Der p II
    • 9 van Neerven RJJ, van't Hof W, Ringrose JH et al. T cell epitopes of house dust mite major allergen Der p II. J Immunol 1993; 151:2326-35.
    • (1993) J Immunol , vol.151 , pp. 2326-2335
    • Van Neerven, R.J.J.1    Van't Hof, W.2    Ringrose, J.H.3
  • 10
    • 0028360199 scopus 로고
    • Overlapping T cell epitopes in the group I allergen of dermatophagoides species restricted by HLA-DP and HLA-DR class II molecules
    • 10 Higgins JA, Thorpe CJ, Hayball JD, O'Hehir RE, Lamb JR. Overlapping T cell epitopes in the group I allergen of Dermatophagoides species restricted by HLA-DP and HLA-DR class II molecules. J Allergy Clin Immunol 1994; 93:891-9.
    • (1994) J Allergy Clin Immunol , vol.93 , pp. 891-899
    • Higgins, J.A.1    Thorpe, C.J.2    Hayball, J.D.3    O'Hehir, R.E.4    Lamb, J.R.5
  • 13
    • 0027153986 scopus 로고
    • Identification of multiple T cell epitopes on Bet v I, the major birch pollen allergen, using specific T cell clones and overlapping peptides
    • 13 Ebner C, Szepfalusi Z, Ferreira F et al. Identification of multiple T cell epitopes on Bet v I, the major birch pollen allergen, using specific T cell clones and overlapping peptides J Immunol 1993; 150:1047-54.
    • (1993) J Immunol , vol.150 , pp. 1047-1054
    • Ebner, C.1    Szepfalusi, Z.2    Ferreira, F.3
  • 14
    • 0028330701 scopus 로고
    • Recognition of T cell epitopes and lymphokine secretion by rye grass allergen lolium perenne I-specific human T cell clones
    • 14 Spiegelberg HL, Beck L, Stevenson RD, Ishioka GY. Recognition of T cell epitopes and lymphokine secretion by rye grass allergen Lolium perenne I-specific human T cell clones. J Immunol 1994; 152:4706-11.
    • (1994) J Immunol , vol.152 , pp. 4706-4711
    • Spiegelberg, H.L.1    Beck, L.2    Stevenson, R.D.3    Ishioka, G.Y.4
  • 15
    • 0026458751 scopus 로고
    • Comparison between two different assays for measurements of allergen-specific IgE and skin prick test in the diagnosis of insect venom allergy
    • 15 Eiken P, Mosbech H, Jacobsen L et al. Comparison between two different assays for measurements of allergen-specific IgE and skin prick test in the diagnosis of insect venom allergy. Allergy 1992; 47:495-7.
    • (1992) Allergy , vol.47 , pp. 495-497
    • Eiken, P.1    Mosbech, H.2    Jacobsen, L.3
  • 17
    • 0029989575 scopus 로고    scopus 로고
    • Group 5 allergens of timothy grass (Phl p 5) bear cross-reacting T cell epitopes with group 1 allergens of rye grass (Lol p 1)
    • 17 Müller W-D, Karamfilov T, Bufe A, Fahlbusch B, Wolf I, Jäger L. Group 5 allergens of Timothy grass (Phl p 5) bear cross-reacting T cell epitopes with group 1 allergens of rye grass (Lol p 1). Int Arch Allergy Immunol 1996; 109:352-5.
    • (1996) Int Arch Allergy Immunol , vol.109 , pp. 352-355
    • Müller, W.-D.1    Karamfilov, T.2    Bufe, A.3    Fahlbusch, B.4    Wolf, I.5    Jäger, L.6
  • 18
    • 0028018482 scopus 로고
    • Molecular basis of cross-reactivity among allergen-specific human T cells: T-cell receptor Va gene usage and epitope structure
    • 18 Mohapatra SS, Mohapatra S, Yang M et al. Molecular basis of cross-reactivity among allergen-specific human T cells: T-cell receptor Va gene usage and epitope structure. Immunology 1994; 81:15-20.
    • (1994) Immunology , vol.81 , pp. 15-20
    • Mohapatra, S.S.1    Mohapatra, S.2    Yang, M.3
  • 19
    • 0025732124 scopus 로고
    • Group V allergens in grass pollen. II. Investigation of group V allergens in pollen from 10 grasses
    • 19 Matthiesen F, Løwenstein H. Group V allergens in grass pollen. II. Investigation of group V allergens in pollen from 10 grasses. Clin Exp Allergy 1991; 21:309-20.
    • (1991) Clin Exp Allergy , vol.21 , pp. 309-320
    • Matthiesen, F.1    Løwenstein, H.2
  • 22
    • 0028913520 scopus 로고
    • Major allergen Phl p 5b in timothy grass is a novel pollen RNase
    • 22 Bufe A, Schramm G, Keown MB, Schlaak M, Becker W-M. Major allergen Phl p 5b in timothy grass is a novel pollen RNase. FEBS Lett 1995; 363:6-12.
    • (1995) FEBS Lett , vol.363 , pp. 6-12
    • Bufe, A.1    Schramm, G.2    Keown, M.B.3    Schlaak, M.4    Becker, W.-M.5
  • 23
    • 0030872895 scopus 로고    scopus 로고
    • Investigation of different recombinant isoforms of grass group-V allergens (timothy grass pollen) isolated by low stringency cDNA hybridization: Antibody binding capacity and allergenic activity
    • 23 Gehlhar K, Petersen A, Schramm G, Becker W-M, Schlaak M, Bufe A. Investigation of different recombinant isoforms of grass group-V allergens (timothy grass pollen) isolated by low stringency cDNA hybridization: antibody binding capacity and allergenic activity. Eur J Biochem 1997; 247:217-23.
    • (1997) Eur J Biochem , vol.247 , pp. 217-223
    • Gehlhar, K.1    Petersen, A.2    Schramm, G.3    Becker, W.-M.4    Schlaak, M.5    Bufe, A.6
  • 24
    • 0029870704 scopus 로고    scopus 로고
    • Immunological characterization of purified recombinant timothy grass pollen (Phleum pratense) allergens (Phl p 1, Phl p 2, Phl p 5)
    • 24 Vrtala S, Susani M, Sperr WR et al. Immunological characterization of purified recombinant Timothy grass pollen (Phleum pratense) allergens (Phl p 1, Phl p 2, Phl p 5). J Allergy Clin Immunol 1996; 97:781-7.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 781-787
    • Vrtala, S.1    Susani, M.2    Sperr, W.R.3
  • 25
    • 0032817225 scopus 로고    scopus 로고
    • Highly heterogenous Phl p 5-specific T cells from patients with allergic rhinitis differentially recognize recombinant Phl p 5 isoallergens
    • 25 Würtzen P, Wissenbach M, Ipsen H, Bufe A, Arnved J, Van Neerven RJ. Highly heterogenous Phl p 5-specific T cells from patients with allergic rhinitis differentially recognize recombinant Phl p 5 isoallergens. J Allergy Clin Immunol 1999; 104: 115-22.
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 115-122
    • Würtzen, P.1    Wissenbach, M.2    Ipsen, H.3    Bufe, A.4    Arnved, J.5    Van Neerven, R.J.6
  • 26
    • 0031956841 scopus 로고    scopus 로고
    • Allergenic activity of a major grass pollen allergen is elevated in the presence of nasal secretion
    • 26 Bufe A, Gehlhar K, Schramm G, Schlaak M, Decker WM. Allergenic activity of a major grass pollen allergen is elevated in the presence of nasal secretion. Am J Respir Crit Care Med 1998; 157:1269-76.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1269-1276
    • Bufe, A.1    Gehlhar, K.2    Schramm, G.3    Schlaak, M.4    Decker, W.M.5
  • 27
    • 0026719899 scopus 로고
    • Nearly identical T-cell receptor V-gene usage at birth in two cohorts of distinctly different ethnic origin: Influence of environment in the final maturation in the adult
    • 27 Ramakrishan NS, Grunewald J, Janson CH, Wigzell H. Nearly identical T-cell receptor V-gene usage at birth in two cohorts of distinctly different ethnic origin: influence of environment in the final maturation in the adult. Scand J Immunol 1992; 36:71-8.
    • (1992) Scand J Immunol , vol.36 , pp. 71-78
    • Ramakrishan, N.S.1    Grunewald, J.2    Janson, C.H.3    Wigzell, H.4
  • 28
    • 0031018430 scopus 로고    scopus 로고
    • Quantitative analysis of the usage of human T cell receptor a and b chain variable regions by reverse dot hybridization
    • 28 Yoshioka T, Matsutani T, Iwagami S et al. Quantitative analysis of the usage of human T cell receptor a and b chain variable regions by reverse dot hybridization. J Immunol Methods 1997; 201:145-55.
    • (1997) J Immunol Methods , vol.201 , pp. 145-155
    • Yoshioka, T.1    Matsutani, T.2    Iwagami, S.3
  • 32
    • 0027222095 scopus 로고
    • Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
    • 32 Varney VA, Hamid QA. Gaga M et al. Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J Clin Invest 1993; 92:644-51.
    • (1993) J Clin Invest , vol.92 , pp. 644-651
    • Varney, V.A.1    Hamid, Q.A.2    Gaga, M.3
  • 33
    • 0030003889 scopus 로고    scopus 로고
    • + T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-g
    • + T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-g. J Allergy Clin Immunol 1996; 97:1356-65.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 1356-1365
    • Durham, S.R.1    Ying, S.2    Varney, V.A.3
  • 34
    • 0028901793 scopus 로고
    • Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFNγ secretion in specific allergen stimulated T cell cultures
    • 34 Jutel M, Pichler WJ, Skrbic D, Urwyler A, Dahinden C, Müller UR. Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFNγ secretion in specific allergen stimulated T cell cultures. J Immunol 1995; 154:4187-94.
    • (1995) J Immunol , vol.154 , pp. 4187-4194
    • Jutel, M.1    Pichler, W.J.2    Skrbic, D.3    Urwyler, A.4    Dahinden, C.5    Müller, U.R.6
  • 35
    • 0025804289 scopus 로고
    • Functional inactivation of dermatophagoides spp. (house dust mite) reactive human T-cell clones
    • 35 O'Hehir RE, Aguilar BA, Schmidt TJ, Gollnick SO, Lamb JR. Functional inactivation of Dermatophagoides spp. (house dust mite) reactive human T-cell clones. Clin Exp Allergy 1991; 21:209-15.
    • (1991) Clin Exp Allergy , vol.21 , pp. 209-215
    • O'Hehir, R.E.1    Aguilar, B.A.2    Schmidt, T.J.3    Gollnick, S.O.4    Lamb, J.R.5
  • 36
    • 0029559917 scopus 로고
    • T-cell epitopes of Phl p 1, major pollen allergen of timothy grass (Phleum pratense): Evidence for cross-reacting and non-cross-reacting T-cell epitopes within grass group I allergens
    • 36 Schenk S, Breiteneder H, Susani M et al. T-cell epitopes of Phl p 1, major pollen allergen of timothy grass (Phleum pratense): evidence for cross-reacting and non-cross-reacting T-cell epitopes within grass group I allergens. J Allergy Clin Immunol 1995; 96:986-96.
    • (1995) J Allergy Clin Immunol , vol.96 , pp. 986-996
    • Schenk, S.1    Breiteneder, H.2    Susani, M.3
  • 37
    • 13344287034 scopus 로고    scopus 로고
    • Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1 : Potential use of hypoallergenic isoforms for immunotherapy
    • 37 Ferreira F, Hirtenlehner K, Jilek A et al. Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1 : potential use of hypoallergenic isoforms for immunotherapy. J Exp Med 1996; 183:599-609.
    • (1996) J Exp Med , vol.183 , pp. 599-609
    • Ferreira, F.1    Hirtenlehner, K.2    Jilek, A.3
  • 38
    • 0030854098 scopus 로고    scopus 로고
    • Engineering of the major house dust mite allergen Der f 2 for allergen-specific immunotherapy
    • 38 Takai T, Yokota T, Yasue M et al. Engineering of the major house dust mite allergen Der f 2 for allergen-specific immunotherapy. Nature Biotechnol 1997; 15:754-8.
    • (1997) Nature Biotechnol , vol.15 , pp. 754-758
    • Takai, T.1    Yokota, T.2    Yasue, M.3
  • 40
    • 0030043151 scopus 로고    scopus 로고
    • Parietaria judaica-specific T-cell clones from atopic patients: Heterogeneity in restriction, VB usage, and cytokine production
    • 40 Sallusto F, Corinti S, Pini C, Biocca MM, Bruno G, Di Felice G. Parietaria judaica-specific T-cell clones from atopic patients: Heterogeneity in restriction, VB usage, and cytokine production. J Allergy Clin Immunol 1996; 97:627-37.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 627-637
    • Sallusto, F.1    Corinti, S.2    Pini, C.3    Biocca, M.M.4    Bruno, G.5    Di Felice, G.6
  • 41
    • 0029006360 scopus 로고
    • Diversity of TCR-Va and TCR-Vb sequences used by human T cell clones specific for a minimal epitope of Bet v 1, the major birch pollen allergen
    • 41 Breiteneder H, Hajek R, Scheiner O et al. Diversity of TCR-Va and TCR-Vb sequences used by human T cell clones specific for a minimal epitope of Bet v 1, the major birch pollen allergen. Immunogenetics 1995; 42:53-8.
    • (1995) Immunogenetics , vol.42 , pp. 53-58
    • Breiteneder, H.1    Hajek, R.2    Scheiner, O.3
  • 42
    • 0032935079 scopus 로고    scopus 로고
    • Identification of a highly promiscuous and an HLA allele-specific T-cell epitope in the birch major allergen Bet v 1 : HLA restriction, epitope mapping and TCR sequence comparisons
    • 42 Friedl-Hajek R, Spangfort MD, Schou C, Breiteneder H, Yssel H, Joost van Neerven RJ. Identification of a highly promiscuous and an HLA allele-specific T-cell epitope in the birch major allergen Bet v 1 : HLA restriction, epitope mapping and TCR sequence comparisons. Clin Exp Allergy 1999; 29:478-87.
    • (1999) Clin Exp Allergy , vol.29 , pp. 478-487
    • Friedl-Hajek, R.1    Spangfort, M.D.2    Schou, C.3    Breiteneder, H.4    Yssel, H.5    Joost Van Neerven, R.J.6
  • 43
    • 0030236150 scopus 로고    scopus 로고
    • Sequence comparisons of the CDR3 hyper-variable loops of human T cell receptors specific for three major T cell epitopes of the birch pollen allergen Bet v 1
    • 43 Breiteneder H, Friedl-Hajek R, Ebner C et al. Sequence comparisons of the CDR3 hyper-variable loops of human T cell receptors specific for three major T cell epitopes of the birch pollen allergen Bet v 1. Mol Immunol 1996; 33:1039-48.
    • (1996) Mol Immunol , vol.33 , pp. 1039-1048
    • Breiteneder, H.1    Friedl-Hajek, R.2    Ebner, C.3


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