Creatine supplementation - Part II: In vivo magnetic resonance spectroscopy

Medicine and Science in Sports and Exercise

Volumn 31, Issue 12, 1999, Pages 1770-1777

  Kreis, Roland ^b   Kamber, Matthias ^b   Koster, Markus ^b   Felblinger, Jacques ^b   Slotboom, Johannes ^b   Hoppeler, Hans ^b   Boesch, Chris ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b NONE

Author keywords

1H MRS; 31P MRS; Creatine phosphate; Ergogenic aid

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE; CREATINE PHOSPHATE; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; EXERCISE; HUMAN; HUMAN EXPERIMENT; MALE; MUSCLE METABOLISM; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE; ORAL DRUG ADMINISTRATION; QUADRICEPS FEMORIS MUSCLE; TIBIALIS ANTERIOR MUSCLE;

EID: 0033385788     PISSN: 01959131     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005768-199912000-00012     Document Type: Article

References (40)

1. BALABAN, R. S. Regulation of oxidative phosphorylation in the mammalian cell. Am. J. Physiol. 258:C377-C389, 1990.
2. BALSOM, P. D., B. EKBLOM, K. SODERLUND, B. SJÖDIN, and E. HULTMAN. Creatine supplementation and dynamic high-intensity intermittent exercise. Scand. J. Med. Sci. Sports 3:143-149, 1993.
3. BALSOM, P. D., S. D. R. HARRIDGE, K. SODERLUND, B. SJÖDIN, and B. EKBLOM. Creatine supplementation per se does not enhance endurance exercise performance. Acta Physiol. Scand. 149:521-523, 1993.
4. BALSOM, P. D., K. SODERLUND, and B. EKBLOM. Creatine in humans with special reference to creatine supplementation. Sports Med. 18:268-280, 1994.
5. BALSOM, P. D., K. SODERLUND, B. SJÖDIN, and B. EKBLOM. Skeletal muscle metabolism during short duration high-intensity exercise: influence of creatine supplementation. Acta Physiol. Scand. 154: 303-310, 1995.
6. BLEI, M. L., K. E. CONLEY, and M. J. KUSHMERICK. Separate measures of ATP utilization and recovery in human skeletal muscle. J. Physiol. 465:203-222, 1993.
7. BLEI, M. L., K. E. CONLEY, I. R. ODDERSON, P. C. ESSELMAN, and M. J. KUSHMERICK. Individual variation in contractile cost and recovery in a human skeletal muscle. Proc. Natl. Acad. Sci. USA 90:7396-7400, 1993.
8. BOTTOMLEY, P. A. U.S. patent no. 4,480,228, 1984.
9. CASEY, A., D. CONSTANTIN-TEODOSIU, S. HOWELL, E. HULTMAN, and P. L. GREENHAFF. Creatine ingestion favorably affects performance and muscle metabolism during maximal exercise in humans. Am. J. Physiol. 271:E31-E37, 1996.
10. EARNEST, C. P., P. G. SNELL, R. RODRIGUEZ, A. L. ALMADA, and T. L. MITCHELL. The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition. Acta Physiol. Scand. 153:207-209, 1995.
11. FEBBRAIO, M. A., T. R. FLANAGAN, R. J. SNOW, S. ZHAO, and M. F. CAREY. Effect of creatine supplementation on intramuscular TCr, metabolism and performance during intermittent, supramaximal exercise in humans. Acta Physiol. Scand. 155:387-395, 1995.
12. FELBLINGER, J., C. LEHMANN, H. HOPPELER, and C. BOESCH. Optical force measurement during MRS studies of human exercise. Proc. SMR Annual Meeting 3:1889-1889, 1995.
13. GREEN, A. L., E. HULTMAN, I. A. MACDONALD, D. A. SEWELL, and P. L. GREENHAFF. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am. J. Physiol. 34:E821-E826, 1996.
14. GREEN, A. L., E. J. SIMPSON, J. J. LITTLEWOOD, I. A. MACDONALD, and P. L. GREENHAFF. Carbohydrate ingestion augments creatine retention during creatine feeding in humans. Acta Physiol. Scand. 158:195-202, 1996.
15. GREENHAFF, P. L. Creatine and its application as an ergogenic aid. Int. J. Sport Nutr. 5:S100-S110, 1995.
16. GREENHAFF, P. L. Creatine supplementation: recent developments (Editorial). Br. J. Sports Med. 30:276-281, 1996.
17. GREENHAFF, P. L., K. BODIN, K. SODERLUND, and E. HULTMAN. Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis. Am. J. Physiol. 266:E725-E730, 1994.
18. GREENHAFF, P. L., A. CASEY, A. H. SHORT, R. HARRIS, K. SODERLUND, and E. HULTMAN. Influence of oral creatine supplementation on muscle torque during repeated bouts of maximal voluntary exercise in man. Clin. Sci. 84:565-571, 1993.
19. HARRIS, R. C., K. SODERLUND, and E. HULTMAN. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin. Sci. 83:367-374, 1992.
20. HENNIG, J. The application of phase rotation for localized in vivo proton spectroscopy with short echo times. J. Magn. Reson. 96: 40-49, 1992.
21. KAMBER, M., M. KOSTER, R. KREIS, G. WALKER, C. BOESCH, and H. HOPPELER. Creatine supplementation and performance. Part I: physical performance, clinical chemistry, and muscle volume. Med. Sci. Sports Exerc. 31:1763-1769, 1999.
22. KEMP, G. J. Interactions of mitochondrial ATP synthesis and the creatine kinase equilibrium in skeletal muscle. J. Theor. Biol. 170:239-246, 1994.
23. KEMP, G. J., and G. K. RADDA. Quantitative interpretation of bioenergetic data from 31P and 1H magnetic resonance spectroscopic studies of skeletal muscle: an analytical review. Magn. Reson. Q. 10:43-63, 1994.
24. KEMP, G. J., D. J. TAYLOR, and G. K. RADDA. Control of phosphocreatine resynthesis during recovery from exercise in human skeletal muscle. NMR Biomed. 6:66-72, 1993.
25. KENT-BRAUN, J. A., R. G. MILLER, and M. W. WEINER. Magnetic resonance spectroscopy studies of the human muscle. Radiol. Clin. North Am. 32:313-335, 1994.
26. KREIS, R., and C. BOESCH. Liquid-crystal-like structures of human muscle demonstrated by in vivo observation of direct dipolar coupling in localized proton magnetic resonance spectroscopy. J. Magn. Reson. Series B 104:189-192, 1994.
27. KREIS, R., T. ERNST, and B. D. ROSS. Absolute quantitation of water and metabolites in the human brain. II. Metabolite concentrations. J. Magn. Reson. Series B 102:9-19, 1993.
28. KREIS, R., M. KOSTER, M. KAMBER, H. HOPPELER, and C. BOESCH. Peak assignment in localized 1H MR spectra of human muscle based on oral creatine supplementation. Magn. Reson. Med. 37:159-163, 1997.
29. MAUGHAN, R. J. Creatine supplementation and exercise performance. Int. J. Sport Nutr. 5:94-101, 1995.
30. MCCULLY, K. K., K. VANDENBORNE, K. DEMEIRLEIR, J. D. POSNER, and J. S. LEIGH. Muscle metabolism in track athletes, using 31P magnetic resonance spectroscopy. Can. J. Physiol. Pharmacol. 70:1353-1359, 1992.
31. MEYER, R. A. A linear model of muscle respiration explains monoexponential phosphocreatine changes. Am. J. Physiol. 254: C548-C553, 1988.
32. MEYER, R. A. Linear dependence of muscle phosphocreatine kinetics on total creatine content. Am. J. Physiol. 257:C1149-C1157, 1989.
33. SLOTBOOM, J., C. BOESCH, and R. KREIS. Versatile frequency domain fitting using time domain models and prior knowledge. Magn. Reson. Med. 39:899-911, 1998.
34. STROUD, M. A., D. HOLLIMAN, D. BELL, A. L. GREEN, I. A. MACDONALD, and P. L. GREENHAFF. Effect of oral creatine supplementation on respiratory gas exchange and blood lactate accumulation during steady-state incremental treadmill exercise and recovery in man. Clin. Sci. 87:707-710, 1994.
35. THOMPSON, C. H., G. J. KEMP, A. L. SANDERSON, et al. Effect of creatine on aerobic and anaerobic metabolism in skeletal muscle in swimmers. Br. J. Sports Med. 30:222-225, 1996.
36. VANDENBERGHE, K., N. GILLIS, M. VANLEEMPUTTE, P. VANHECKE, F. VANSTAPEL, and P. HESPEL. Caffeine counteracts the ergogenic action of muscle creatine loading. J. Appl. Physiol. 80:452-457, 1996.
37. VANDENBERGHE, K., M. GORIS, P. VAN HECKE, M. VAN LEEMPUTTE, L. VANGERVEN, and P. HESPEL. Long-term creatine intake is beneficial to muscle performance during resistance training. J. Appl. Physiol. 83:2055-2063, 1997.
38. WALLIMANN, T., M. WYSS, D. BRDICZKA, K. NICOLAY, and H. M. EPPENBERGER. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the "phosphocreatine circuit" for cellular energy homeostasis. Biochem. J. 281:21-40, 1992.
39. YOSHIDA, T., and H. WATARI. P-31-nuclear magnetic resonance study of the time course of energy metabolism during exercise and recovery. Eur. J. Appl. Physiol. 66:494-499, 1993.
40. VANDENBERGHE K., P. VAN HECKE, M. VAN LEEMPUTTE, F. VANSTAPEL, and P. HESPEL. Phosphocreatine resynthesis is not affected by creatine loading. Med. Sci. Sports Exerc. 31:236-242, 1999.