Influence of chronic treatment with imipramine on mRNA levels in rat brain: Elevation of glyceraldehyde-3-phosphate dehydrogenase levels

Japanese Journal of Pharmacology

Volumn 81, Issue 4, 1999, Pages 393-396

  Tohda, Michihisa ^a   Qi, Zhao ^a   Watanabe, Hiroshi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Antidepressant; Differential display; Glyceraldehyde 3 phosphate dehydrogenase

Indexed keywords

ANTIDEPRESSANT AGENT; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMIPRAMINE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN LEVEL; CONTROLLED STUDY; DISPLAY SYSTEM; DOSE TIME EFFECT RELATION; DRUG MECHANISM; ENZYME SYNTHESIS; GENE EXPRESSION; LONG TERM EXPOSURE; NONHUMAN; POLYMERASE CHAIN REACTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADRENERGIC UPTAKE INHIBITORS; ANIMALS; BRAIN; BRAIN CHEMISTRY; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; IMIPRAMINE; IN SITU HYBRIDIZATION; MALE; POLYMERASE CHAIN REACTION; RATS; RATS, WISTAR; RNA PROBES; RNA, MESSENGER;

EID: 0033383525     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.81.393     Document Type: Article

References (15)

1. Barker EL and Blakely RD: Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with human serotonin transporter. Mol Pharmacol 50, 957-965 (1996)
2. Tohda M and Watanabe H: Imipramine-induced increase in 5-HT2C receptor mRNA level in the rat brain. Neurosci Res 24, 189-193 (1996)
3. Tohda M and Watanabe H: Enhancement of serotonin 2C receptor mRNA expression by antidepressants possessing the receptor-blocking activity in the rat brain. Jpn J Pharmacol 78, 515-517 (1998)
4. Tohda M, Nomura Y and Watanabe H: Effects of imipramine on 5-HT2C mRNA and a novel depression related gene (DRF24) expression. Soc Neurosci Abstr 22, 943 (1996)
5. Chomczynski P and Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162, 156-159 (1987)
6. Liang P and Pardee AB: Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257, 967-971 (1992)
7. Tso JY, Sun XH, Kao TH, Reece KS and Wu R: Isolation and Characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNA: genomic complexity and molecular evolution of the gene. Nucleic Acids Res 13, 2485-2502 (1985)
8. Bonaldo MF, Lennon G and Soares MB: Normalization and subtraction: two approaches to facilitate gene discovery. Genome Res 6, 791-806 (1996)
9. Zhong H and Simons JW: Direct comparison of GAPDH, beta-actin, cyclophilin, and 28S rRNA as internal standards for quantifying RNA levels under hypoxia. Biochem Biophys Res Commun 259, 523-526 (1999)
10. Hazell AS, Desjardins P and Butterworth RF: Increased expression of glyceraldehyde-3-phosphate dehydrogenase in cultured astrocytes following exposure to manganese. Neurochem Int 35, 11-17 (1999)
11. Graven KK, McDonald RJ and Farber HW: Hypoxic regulation of endothelial glyceraldehyde-3-phosphate dehydrogenase. Am J Physiol 274, C347-C355 (1998)
12. Tokunaga K, Nakamura Y, Sakata K, Fujimori K, Ohkubo M, Sawada K and Sakiyama S: Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. Cancer Res 47, 5616-5619 (1987)
13. Shinohara ML, Loros JJ and Dunlap JC: Glyceraldehyde-3-phosphate dehydrogenase is regulated on a daily basis by the circadian clock. J Biol Chem 273, 446-452 (1998)
14. Boyer PA, Skolnick P and Fossom LH: Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNA in mouse brain. A quantitative in situ hybridization study. J Mol Neurosci 10, 219-233 (1998)
15. Suda S, Nibuya M, Ishiguro T and Suda H: Transcription and translational regulation of phosphodiesterase type IV isozymes in rat brain by electroconvulsive seizure and antidepressant drug treatment. J Neurochem 71, 1554-1563 (1998)