Synthesis and in vivo evaluation of [11C]SA6298 as a PET sigma1 receptor ligand

Nuclear Medicine and Biology

Volumn 26, Issue 8, 1999, Pages 915-922

  Kawamura, Kazunori ^a,b   Ishiwata, Kiichi ^a   Tajima, Hisashi ^c   Ishii, Shin Ichi ^a   Shimada, Yuhei ^a,d   Matsuno, Kiyoshi ^c   Homma, Yoshio ^b   Senda, Michio ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c SANTEN PHARMACEUTICAL CO LTD   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Carbon 11; Positron emission tomography; SA6298; Sigma receptor

Indexed keywords

1 (3,4 DIMETHOXYPHENETHYL) 4 (3 PHENYLPROPYL)PIPERAZINE; 2 [4 METHOXY 3 (2 PHENYLETHOXY)PHENYL] N,N DIPROPYLETHYLAMINE; CARBON 11; HALOPERIDOL; N ALLYLNORMETAZOCINE; PENTAZOCINE; PIPERAZINE DERIVATIVE; PRECLAMOL; SA 6298; SIGMA 1 OPIATE RECEPTOR; SIGMA RECEPTOR LIGAND; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING KINETICS; BRAIN REGION; CONTROLLED STUDY; DRUG INHIBITION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; DRUG UPTAKE; MALE; METHYLATION; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT; RECEPTOR AFFINITY;

ANIMALS; BIOTRANSFORMATION; BRAIN; BRAIN CHEMISTRY; CARBON RADIOISOTOPES; CATS; FEMALE; GUINEA PIGS; INDICATORS AND REAGENTS; ISOTOPE LABELING; LIGANDS; MALE; MICE; PIPERAZINES; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; RECEPTORS, SIGMA; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0033382775     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(99)00069-4     Document Type: Article

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