Cesium induces spontaneous epileptiform activity without changing extracellular potassium regulation in rat hippocampus

Journal of Neurophysiology

Volumn 82, Issue 6, 1999, Pages 3339-3346

  Xiong, Zhi Qi ^a   Stringer, Janet L ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 4 (N ETHYL N PHENYLAMINO) 1,2 DIMETHYL 6 (METHYLAMINO)PYRIMIDINIUM CHLORIDE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; CESIUM; ION CHANNEL; POTASSIUM CHANNEL; POTASSIUM ION;

ANIMAL CELL; ARTICLE; BRAIN SLICE; EPILEPTIC DISCHARGE; EPILEPTOGENESIS; FEMALE; HIPPOCAMPUS; MALE; NERVE CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT;

EID: 0033377371     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1999.82.6.3339     Document Type: Article

References (31)

1. BALLANYI, K., GRAFE, P., AND BRUGGENCATE, G. T. Ion activities and potassium uptake mechanisms of glial cells of guinea-pig olfactory cortex slices. J. Physiol. (Lond.) 382: 159-174, 1987.
2. BAYLISS, D. A., VIANA, F., BELLINGHAM, M. C., AND BERGER, A. J. Characteristics and postnatal development of a hyperpolarization-activated inward current in rat hypoglossal motoneurons in vitro. J. Neurophysiol. 71: 119-128, 1994.
3. + buffer capacity, and morphology of glial cells in the corpus callosum slice. J. Neurosci. 11: 3008-3024, 1991.
4. BIKSON, M., BARABAN, S. C., AND DURAND, D. M. Inhibition of nonsynaptic epileptiform activity in the hippocampus. Soc. Neurosci. Abstr. 24: 1213, 1998
5. CASULLO, J. AND KRNJEVIC, K. Glial potentials in hippocampus. Can. J. Physiol. Pharmacol. 65: 847-855, 1987.
6. D'AMBROSIO, R., WENZEL, J., SCHWARTZKROIN, P. A., MCKHANN, G. M., II, AND JANIGRO, D. Functional specialization and topographic segregation of hippocampal astrocytes. J. Neurosci. 18: 4425-4438, 1998.
7. DUFFY, S., FRASER, D. D., AND MACVICAR, B. A. Potassium channels. In: Neuroglia, edited by H. Kettenmann and B. R. Ransom. New York: Oxford Univ. Press, 1995, p. 185-201.
8. GASPARINI, S. AND DIFRANCESCO, D. Action of the hyperpolarization-activated current (Ih) blocker ZD 7288 in hippocampal CA1 neurons. Pflügers Arch. 435: 99-106, 1997.
9. GUATTEO, E., STANNESS, K. A., AND JANIGRO, D. Hyperpolarization-activated currents in cultured rat cortical and spinal cord astrocytes. Glia 16: 196-209, 1996.
10. HARRIS, N. C. AND CONSTANTI, A. Mechanism of block by ZD 7288 of the hyperpolarization-activated inward rectifying current in guinea pig substantia nigra neurons in vitro. J. Neurophysiol. 74: 2366-2378, 1995.
11. HWA, G.G.C. AND AVOLI, M. The effects of cesium on the synaptic and intrinsic properties of neocortical neurons maintained "in vitro." Soc. Neurosci. Abstr. 15: 77, 1989.
12. HWA, G.G.C. AND AVOLI, M. Cesium potentiates epileptiform activities induced by bicuculline methiodide in rat neocortex maintained in vitro. Epilepsia. 32: 747-754, 1991.
13. + uptake in glia prevents LTD maintenance and causes epileptiform activity. J. Neurosci. 17: 2813-2824, 1997.
14. +-dependent inhibition in weaver hippocampus J. Neurosci. 18: 4001-4007, 1998.
15. JAROLIMEK, W., BIJAK, M., AND MISGELD, U. Differences in the Cs block of baclofen and 4-aminopyridine induced potassium currents of guinea pig CA3 neurons in vitro. Synapse 18: 169-177, 1994.
16. JOHNS, D. C., MARX, R., MAINS, R. E., O'ROURKE, B., AND MARBÁN, E. Inducible genetic suppresion of neuronal excitability. J. Neurosci. 19: 1691-1697, 1999.
17. +-channel blockers on transmitter release in bullfrog sympathetic ganglia. J. Pharmacol. Exp. Ther. 235: 241-247, 1985.
18. MACCAFERRI, G., MANGONI, M., LAZZARI, A., AND DIFRANCESCO, D. Properties of the hyperpolarization-activated current in rat hippocampal CA1 pyramidal cells. J. Neurophysiol. 69: 2129-2136, 1993.
19. MACCAFERRI, G., JANIGRO, D., LAZZARI, A., AND DIFRANCESCO, D. Cesium prevents maintenance of long-term depression in rat hippocampal CA1 neurons. Neuroreport 5: 1813-1816, 1994.
20. NEWMAN, E. A. Glial cell regulation of extracellular potassium. In: Neuroglia, edited by H. Kettenmann and B. R. Ransom. New York: Oxford Univ. Press, 1995, p. 717-731.
21. PAN, E. AND STRINGER, J. L. Burst characteristics of dentate gyrus granule cells: evidence for endogenous and nonsynaptic properties. J. Neurophysiol 75: 124-132, 1996.
22. RANSOM, C. B. AND SONTHEIMER, H. Biophysical and pharmacological characterization of inwardly rectifying potassium currents in rat spinal cord astrocytes. J. Neurophysiol. 73: 333-346, 1995.
23. SCHWEITZER, J. S., PATRYLO, P. R., AND DUDEK, F. E. Prolonged field bursts in the dentate gyrus: dependence on low calcium, high potassium, and nonsynaptic mechanisms. J. Neurophysiol. 68: 2016-2025, 1992.
24. SIGNORINI, S., LIAO, Y. J., DUNCAN, S. A., JAN, L. Y., AND STOFFEL, M. Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2. Proc. Natl. Acad. Sci. USA 94: 923-927, 1997.
25. SODICKSON, D. L. AND BEAN, B. P. Neurotransmitter activation of inwardly rectifying potassium current in dissociated hippocampal CA3 neurons: interactions among multiple receptors. J. Neurosci. 18: 8153-8162, 1998.
26. SOLIVEN, B., SZUCHET, S., ARNASON, B.G.W., AND NELSON, D. G. Voltagegated potassium currents in cultured ovine oligodendrocytes. J. Neurosci. 8: 2131-2141, 1988.
27. SONTHEIMER, H. AND WAXMAN, S. G. Expression of voltage-activated ion channels by astrocytes and oligodendrocytes in the hippocampal slice. J. Neurophysiol. 70: 1863-1873, 1993.
28. SPAIN, W. J., SCHWINDT, P. C. AND CRILL, W. E. Anomalous rectification in neurons from cat sensorimotor cortex in vitro. J. Neurophysiol. 57: 1555-1576, 1987.
29. o response patterns. Epilepsy Res. 4: 177-186, 1989.
30. WILLIAMS, J. T., COLMERS, W. F., AND PAN Z. Z. Voltage- and ligand-activated inwardly rectifying currents in dorsal raphe neurons in vitro. J. Neurosci. 8: 3499-3506, 1988.
31. ZAREI, M. M. AND DANI, J. A. Ionic permeability characteristics of the N-methyl-D-aspartate receptor channel. J. Gen. Physiol. 103: 231-248, 1994.