Inducible types of cyclooxygenase and nitric oxide synthase in adaptive cytoprotection in rat stomachs

Journal of Physiology Paris

Volumn 93, Issue 5, 1999, Pages 405-412

  Yamamoto, Hideichiro ^a   Tanaka, Akiko ^a   Kunikata, Tomonori ^a   Hirata, Takuya ^a   Kato, Shinichi ^a   Takeuchi, Koji ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

0.6 N HCl; Adaptive cytoprotection; COX 1; COX 2; Gastric mucosa; INOS; Nitric oxide; NNOS; Prostaglandin; Taurocholate

Indexed keywords

AMINOGUANIDINE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; HYDROCHLORIC ACID; INDOMETACIN; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE INHIBITOR; TAUROCHOLIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; CELL PROTECTION; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION; MALE; NONHUMAN; PROSTAGLANDIN SYNTHESIS INHIBITION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH MUCOSA; STOMACH ULCER;

EID: 0033373139     PISSN: 09284257     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-4257(99)00128-X     Document Type: Conference Paper

References (34)

1. Bredt D.S., Hwang P.M., Glatt C.J., Lowenstein C., Reed R.R., Snyder S.H. Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature. 351:1991;714-718.
2. Feng L., Sun W., Xia Y., Tang W.W., Chanmugam P., Soyoola E., Wilson C.B., Hwang D. Cloning two isoforms of rat cyclooxygenase: Differential regulation of their expression. Arch. Biochem. Biophys. 307:1993;361-368.
3. Futaki N., Takahashi S., Yokoyama M., Arai I., Higuchi S., Otomo S. NS-938, a new antiinflammatory agent, selectively inhibits prostaglandin G/H synthase/ cyclooxygenase (COX-2) activity in vitro. Prostaglandins. 47:1994;55-59.
4. 15N-nitrate in biological fluids. Anal. Biochem. 126:1982;131-138.
5. Gretzer B., Ehrlich K., Maricic N., Lambrecht N., Respondek M., Peskar B.M. Selective cyclo-oxygenase-2 inhibitors and their influence on the protective effect of a mild irritant in the rat stomach. Br. J. Pharmacol. 123:1998;927-935.
6. Griffiths M.J.D., Messent M., MacAllister R.J., Evans T.W. Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br. J. Pharmacol. 110:1993;963-968.
7. Hirata T., Ukawa H., Yamakuni H., Kato S., Takeuchi K. Cyclooxygenase isozymes in acute mucosal ulcerogenic and functional responses following barrier disruption in rat stomachs. Br. J. Pharmacol. 122:1997;447-454.
8. Iso J.Y., Sun X.H., Kao T.H., Reece K.S., Wu R. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene. Nucleic Acids Res. 13:1995;2485-2502.
9. Kato S., Tanaka A., Konaka A., Kunikatav, Takeuchi K. Aggravation of indomethacin-induced gastric mucosal lesions in adjuvant arthritis rats. Aliment. Pharmacol. Ther. 13:1999;833-840.
10. Konturek P.C., Brzozowski T., Konturek S.J., Taut A., Kwiecien S., Pajdo R., Sliwowski Z., Hahn E.G. Bacterial lipopolysaccharide protects gastric mucosa against acute injury in rats by activation of genes for cyclooxygenases and endogenous prostaglandins. Digestion. 59:1998;284-297.
11. Lyons C.R., Orloff G.J., Cunningham J.M. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J. Biol. Chem. 267:1992;6370-6374.
12. Moncada S., Palmer R.M.J., Higgs E.A. Nitric oxide: Physiology, patho-physiology and pharmacology. Pharmacol. Rev. 43:1991;109-142.
13. Morita I., Schindler M., Regier M.K., Otto J.C., Hori T., DeWitt D.L., Smith W.L. Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2. J. Biol. Chem. 270:1995;10902-10908.
14. Mourelle M., Vllaseca J., Guarner P., Salas A., Malagelada J.R. Toxic dilation of colon in a rat model of colitis is linked to an inducible form of nitric oxide synthase. Am. J. Physiol. 270:1996;G425-G430.
15. Nakatsugi S., Terada N., Yoshimura T., Horie Y., Furukawa M. Effects of nimesulide, a prefential cyclooxygenase-2 inhibitor, on carrageenan-induced pleurisy and stress-induced gastric lesions in rats. Prostaglandins Leukotrines Essential Fatty Acids. 55:1996;395-402.
16. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 6:1992;3051-3064.
17. O'Banion M.K., Sadowski H.B., Winn V., Young D.A. A serum- and gluco-corticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein. J. Biol. Chem. 266:1991;23261-23267.
18. O'Neill G.P., Ford-Hutchinson A.W. Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett. 330:1993;156-160.
19. Ribbons R.A., Zhang X.J., Thompson v., Greenberg S.S., Moore W.M., Kornmeir C.M., Currie M.G., Lerche N., Blanchard J., Clark D.A., Miller M.J.S. Potential role of nitric oxide in a model of chronic colitis in rhesus macaques. Gastroenterology. 108:1995;705-711.
20. Robert A. Cytoprotection by prostaglandins. Gastroenterology. 77:1979;761-767.
21. Robert A., Ruwart M. Effects of prostaglandins on the digestive system. Lee J.B. Prostaglandins. 1982;113-176 Elsevier, New York.
22. Salvemini D., Seibert K., Masferrer J.L., Misko T.P., Currie M.G., Needleman P. Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J. Clin. Invest. 93:1994;1940-1947.
23. Simmons D.L., Xie W., Chipman J.G., Evett G.E. Multiple cyclooxygenases: Cloning of a mitogen inducible from. Bailey J.M. Prostaglandins, Leukotrienes, Lipoxins, and PAF. 1991;67-78 Plenum Press, New York.
24. Takeuchi K., Ohono T., Okabe S. Irritative and protective activity of mild irritants in rat stomach. Dig. Dis. Sci. 32:1987;889-896.
25. Takeuchi K., Takehara K., Kaneko T., Okabe S. Nitric oxide and prostaglandins in regulation of acid secretory response in rat stomach following injury. J. Pharmacol. Exp. Ther. 272:1995;357-363.
26. Takeuchi K., Ohuchi T., Narita M., Okabe S. Capsaicin-sensitive sensory nerves in recovery of gastric mucosal integrity after damage by sodium taurocholate in rats. Jpn. J. Pharmacol. 63:1993;479-485.
27. Tepperman B.L., Soper B.D. Nitric oxide synthase induction and cyto-protection of rat gastric mucosa from injury by ethanol. Can. J. Physiol. Pharmacol. 72:1994;1308-1312.
28. Uno H., Arakawa T., Fukuda T., Yu H., Fujiwara Y., Higuchi K., Inoue M., Kabayashi K. Nitric oxide stimulates prostaglandin synthesis in cultured rabbit gastric cells. Prostaglandins. 53:1997;153-162.
29. Vane J.R., Botting R.M. New insights into the mode of action of anti-inflammatory drugs. Inflamm. Res. 44:1995;1-10.
30. Whittle B.J.R., Lopez-Belmonte J., Moncada S. Regulation of gastric mucosal integrity by endogenous nitric oxide: Interactions with prostanoids and sensory neuropeptides in the rat. Br. J. Pharmacol. 99:1990;607-611.
31. 2 in nitroprusside-stimulated rat colonic ion transport. Am. J. Physiol. 270:1996;C832-C840.
32. Xie W., Robertson D.L., Simmons D.L. Mitogen-inducible prostaglandin G/H synthase: a new target for nonsteroidal antiinflammatory drugs. Drug Dev. Res. 25:1992;249-265.
33. Yasuhiro T., Konaka A., Kato S., Takeuchi K. Gastric mucosal damage induced by compound 48/80: Roles of serotonin and nitric oxide. J. Gastroenterol. Hepatol. 13:1998;1099-1106.
34. Yu H., Sato E.F., Minamiyama Y., Arakawa T., Kobayashi K., Inoue M. Effect of nitric oxide on stress-induced gastric mucosal injury in the rat. Digestion. 58:1997;311-318.