CD44

Journal of Biological Regulators and Homeostatic Agents

Volumn 13, Issue 4, 1999, Pages 234-239

  Kremmidiotis, G ^a  

^a WOMEN S AND CHILDREN S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD44V ANTIGEN; HERMES ANTIGEN;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARCINOGENESIS; CELL ADHESION; CELL MIGRATION; CELLULAR DISTRIBUTION; CHROMOSOME 11P; CHROMOSOME 2; EPITHELIUM; EXON; GENE MAPPING; GENE STRUCTURE; GENETIC TRANSCRIPTION; HEART MUSCLE; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; KNOCKOUT MOUSE; LIVER CELL; LYMPHOID CELL; MOLECULAR INTERACTION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SKIN; T LYMPHOCYTE; TESTIS; THROMBOCYTE; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0033303209     PISSN: 0393974X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (91)

1. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons
2. A PCR-based method for the analysis of human CD44 splice products
3. Identification of mRNA that encodes an alternative form of H-CAM(CD44) in lymphoid and nonlymphoid tissues
4. Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man
5. Lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family
6. The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells
7. Human keratinocytes express a new CD44 core protein (CD44E) as a heparan-sulfate intrinsic membrane proteoglycan with additional exons
8. Molecular cloning and expression of Pgp-1. The mouse homolog of the human H-CAM (Hermes) lymphocyte homing receptor
9. Post-translational protein modification and expression of ankyrin-binding site(s) in GP85 (Pgp-1/CD44) and its biosynthetic precursors during T-lymphoma membrane biosynthesis
10. The identification of a new alternative exon with highly restricted tissue expression in transcripts encoding the mouse Pgp-1 (CD44) homing receptor. Comparison of all 10 variable exons between mouse, human, and rat
11. Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons
12. The cDNA sequence of mouse Pgp-1 and homology to human CD44 cell surface antigen and proteoglycan core/link proteins
13. Variations in the cytoskeletal interaction and post-translational modification of the CD44 homing receptor in macrophages
14. A human lymphocyte homing receptor, the hermes antigen, is related to cartilage proteoglycan core and link proteins
15. The hyaluronate receptor is preferentially expressed on proliferating epithelial cells
16. Expression of two isoforms of CD44 in human endometrium
17. Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms
18. Expression and modulation of CD44 variant isoforms in humans
19. CD44 variant isoforms are preferentially expressed in basal epithelial of non-malignant human fetal and adult tissues
20. Menstrual cycle dependent expression of CD44 in normal human endometrium
21. New CD44 splice variants associated with human breast cancers
22. CD44 variant isoforms in non-Hodgkin's lymphoma: A new independent prognostic factor
23. Confirmation by peptide sequence and co-expression on various cell types of the identity of CD44 and P85 glycoprotein
24. Identification of a widely distributed 90-kDa glycoprotein that is homologous to the Hermes-1 human lymphocyte homing receptor
25. Activated human lymphocytes and aggressive non Hodgkin's lymphomas express a homologue of the rat metastasis-associated variant of CD44
26. Lutheran antigens, CD44-related antigens, and Lutheran regulatory genes
27. Changes in CD44 expression during B cell differentiation in the human tonsil
28. Heterogeneity of CD44 expression among human B-cell subpopulations
29. CD44 is the principal cell surface receptor for hyaluronate
30. Characterization of the class III collagen receptor, a phosphorylated, transmembrane glycoprotein expressed in nucleated human cells
31. A cell surface chondroitin sulfate proteoglycan, immunologically related to CD44, is involved in type I collagen-mediated melanoma cell motility and invasion
32. Effect of transforming growth factor-beta 1 and basic fibroblast growth factor on the expression of cell surface proteoglycans in human lung fibroblasts. Enhanced glycanation and fibronectin-binding of CD44 down-regulation of glypican
33. Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin
34. Distinct effects of two CD44 isoforms on tumor growth in vivo
35. Identification of hyaluronic acid binding sites in the extracellular domain of CD44
36. Monoclonal antibodies against the CD44 [In(Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors
37. A novel ligand for CD44 is serglycin, a hematopoietic cell lineage-specific proteoglycan. Possible involvement in lymphoid cell adherence and activation
38. Receptorligand interaction between CD44 and osteopontin (Eta-1)
39. The chondroitin sulfate form of invariant chain can enhance stimulation of T-cell responses through interaction with CD44
40. Identification of CD44 residues important for hyaluronan binding and delineation of the binding site
41. Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation
42. Glycosylation of CD44 negatively regulates its recognition of hyaluronan
43. Role of CD44 cytoplasmic domain in hyaluronan binding
44. Hyaluronan binding by CD44 is regulated by a phosphorylation-independent mechanism
45. Variant exons v6 and v7 together expand the repertoire of glycosaminoglycans bound by CD44
46. Chondroitin sulphate composition and structure in alternatively spliced CD44 fusion proteins
47. The importance of cellular environment to function of the CD44 matrix receptor
48. Hyaluronic acid-induced lymphocyte signal transduction and HA receptor (GP85/CD44)-cytoskeleton interaction
49. CD44 triggering enhances human NK cell cytotoxic functions
50. Antibodies to CD44 trigger effector functions of human T-cell clones
51. Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures
52. Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition
53. Hyaluronic acid enhances cell proliferation during eosinopoiesis through the CD44 surface antigen
54. CD44 (Pgp-1) inhibits CD3 and dexamethasone-induced apoptosis
55. CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor
56. T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1 beta
57. Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon
58. Homing receptors and vascular addressins: Cell adhesion molecules that direct lymphocyte traffic
59. CD44 and its interaction with extracellular matrix
60. Human T-lymphocyte adhesion to endothelial cells and transendothelial migration. Alteration of receptor use relates to the activation status of both the T-cell and the endothelial cell
61. Requirement for CD44 in activated T-cell extravasation into an inflammatory site
62. Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesion
63. Hyaluronan-binding proteins in development, tissue homeostasis, and disease
64. Hyaluronan receptor-directed assembly of chondrocyte pericellular matrix
65. Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis
66. CD44H regulates tumor cell migration on hyaluronate-coated substrate
67. Migration of human melanoma cells on hyaluronate is related to CD44 expression
68. The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan
69. Binding and degradation of hyaluronan by human breast cancer cell lines expressing different forms of CD44: Correlation with invasive potential
70. Cytokine regulation of human lung fibroblast hyaluronan (hyaluronic acid) production. Evidence for cytokine-regulated hyaluronan (hyaluronic acid) degradation and human lung fibroblast-derived hyaluronidase
71. Hyaluronan receptor (CD44) expression and function in human peripheral blood monocytes and alveolar macrophages
72. Isolation and characterization of human melanoma cell variants expressing high and low levels of CD44
73. HIV-induced loss of CD44 expression in monocytic cell lines
74. Homotypic cell aggregation via conformational change of CD44 molecule induced by anti-CD44 monoclonal antibodies
75. Beta 2-integrin dependent aggregate formation between LB T-cell lymphoma and spleen cells: Assessment of correlation with spleen invasiveness
76. The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules
77. Stimulation of T-cells via CD44 requires leukocyte-function-associated antigen interactions and interleukin-2 production
78. A CD44 monoclonal antibody differentially regulates CD11a/CD18 binding to intercellular adhesion molecules CD54, CD102 and CD50
79. Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function
80. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells
81. Retardation of metastatic tumor growth after immunization with metastasis-specific monoclonal antibodies
82. Prevention of tumor metastasis formation by anti-variant CD44
83. The two major CD44 proteins expressed on a metastatic rat tumor cell line are derived from different splice variants: Each one individually suffices to confer metastatic behavior
84. Elevated serum CD44 level is associated with unfavorable outcome in non-Hodgkin's lymphoma
85. A human homologue of the rat metastasis-associated variant of CD44 is expressed in colorectal carcinomas and adenomatous polyps
86. Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression
87. Colorectal cancer prognosis and expression of exon-v6-containing CD44 proteins
88. CD44 variant exon epitopes in primary breast cancer and length of survival
89. Soluble CD44 splice variants in metastasizing human breast cancer
90. Rapid analysis of distinctive CD44 RNA splicing preferences that characterize colonic tumors
91. Transient absence of CD44 expression and delay in development by anti-CD44 treatment during ontogeny: A surrogate of an inducible knockout?