Inhibition of human mitochondrial aldehyde dehydrogenase by metabolites of disulfiram and structural characterization of the enzyme adduct by HPLC-tandem mass spectrometry

Advances in Experimental Medicine and Biology

Volumn 463, Issue , 1999, Pages 61-70

  Mays, D C ^a   Tomlinson, A J ^a   Johnson, K L ^a   Lam, J ^a   Lipsky, J J ^a   Naylor, S ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; CYSTEINE; DISULFIRAM; DRUG METABOLITE; GLUTATHIONE; MITOCHONDRIAL ENZYME; RECOMBINANT ENZYME;

CONFERENCE PAPER; CONTROLLED STUDY; COVALENT BOND; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME MODIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY;

EID: 0033282422     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-4735-8_8     Document Type: Conference Paper

References (24)

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