Role of nitric oxide and cGMP system in regulation of ductus arteriosus tone in ovine fetus

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 271, Issue 6 40-6, 1996, Pages

  Fox, Jonathan J ^a   Ziegler, James W ^b   Ivy, D Dunbar ^b   Halbower, Ann C ^b   Kinsella, John P ^b   Abman, Steven H ^b  

^a CHILDREN S HOSPITAL   (United States)

^b NONE

Author keywords

cyclooxygenase; guanylate cyclase; indomethacin; lung development; methylene blue; N(G) nitro L arginine; prostaglandins

Indexed keywords

CYCLIC GMP; GUANYLATE CYCLASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; AORTA PRESSURE; ARTERY TONE; ARTICLE; BLOOD FLOW VELOCITY; DUCTUS ARTERIOSUS; ENZYME ACTIVITY; FETUS; LUNG ARTERY PRESSURE; LUNG CIRCULATION; LUNG DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SHEEP;

EID: 0030445808     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.271.6.h2638     Document Type: Article

References (41)

1. Abman, S. H., and F. J. Accurso. Acute effects of partial compression of ductus arteriosus on fetal pulmonary circulation. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H626-H634, 1989.
2. Abman, S. H., F. J. Accurso, R. M. Ward, and R. B. Wilkening. Adaptation of fetal pulmonary blood flow to local infusions of tolazoline. Pediatr. Res. 20:1131-1135, 1986
3. Abman, S. H., B. A. Chatfield, S. A. Hall, and I. F. McMurtry. Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth. Am. J. Physiol. 259 (Heart Circ. Physiol. 28): H1921-H1927, 1990.
4. Brune, B., and V. Ullrich. Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol Pharmacol. 32: 497-504, 1987.
5. Cassin, S., G. S. Dawes, and B. B. Ross. Pulmonary blood flow and vascular resistance in immature fetal lambs. J. Physiol. Lond. 171: 80-89, 1964.
6. Christodoulides, N., W. Durante, M. H. Kroll, and A. I. Schafer. Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide. Circulation 91: 2306-2309, 1995.
7. Clyman, R. I. Developmental physiology of the ductus arteriosus. In: Fetal and Neonatal Cardiology (1st ed.), edited by W. A. Long. Philadelphia, PA: Saunders, 1990, p. 64-75.
8. 2) by the ductus arteriosus of fetal lambs at different stages of gestation. Prostaglandins 16: 633-641, 1978.
9. 2 concentrations and patent ductus arteriosus in fetal and neonatal lambs. J. Pediatr. 97: 455-461, 1980.
10. Coceani, F., C. A. Breen, J. G. Lees, J. R. Falck, and P. M. Olley. Further evidence implicating a cytochrome P-450-mediated reaction in the contractile tension of the lamb ductus arteriosus. Circ Res. 62. 472-477, 1988.
11. Coceani, F., L. Kelsey, and E. Seidlitz. Evidence for an effector role of endothelin in closure of the ductus arteriosus at birth. Can. J. Physiol. Pharmacol. 70: 1061-1064, 1992.
12. Coceani, F., L. Kelsey, and E. Seidlitz. Occurrence of endothelium-derived relaxing factor-nitric oxide in the lamb duetus arteriosus. Can. J. Physiol. Pharmacol. 72:82-88, 1994.
13. Coceani, F., and P. M. Olley. The response of the ductus arteriosus to prostaglandins. Can. J. Physiol. Pharmacol. 60: 345-349, 1973.
14. Cornfield, D. N., B. A. Chatfield, J. A. McQueston, I. F. McMurtry, and S. H. Abman. Effects of birth-related stimuli on L-arginine-dependent pulmonary vasodilation in ovine fetus. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H1474-H1481, 1992.
15. Fay, F. S. Guinea pig ductus arteriosus. I. Cellular and metabolic basis for oxygen sensitivity. Am. J. Physiol. 221: 470-479, 1971.
16. Fineman, J. R., M. R. Crowley, M. A. Heymann, and S. J. Soifer. In vivo attenuation of endothelium-dependent pulmonary vasodilation by methylene blue. J. Appl. Physiol. 71: 735-741, 1991.
17. Fox, J. J., J. W. Ziegler, J. P. Kinsella, D. D. Ivy, A. C. Halbower, and S. H. Abman. Role of nitric oxide-cGMP system in regulation of tone of the ovine ductus arteriousus (Abstract). Pediatr. Res. 37: 76A, 1995.
18. Friedman, W. F., M. P. Printz, S. E. Kirkpatrick, and E. J. Hoskins. The vasoactivity of the fetal lamb ductus arteriosus studied in utero. Pediatr. Res. 17: 331-337, 1983.
19. Furchgott, R. F., and D. Jothianandan. Endothelium-dependent and independent vasodilation involving cyclic GMP: relaxation induced by nitric oxide, carbon monoxide and light. Blood Vessels 28: 52-61, 1991.
20. Gruetter, C. A., D. Y. Gruetter, J. E. Lyon, P. J. Kadowitz, and L. J. Ignarro. Relationship between cyclic 3′,5′-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trintrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin. J. Pharmacol. Exp. Ther. 219:181-186, 1981.
21. Heymann, M. A., R. K. Creasy, and A. M. Rudolph. Quantitation of blood flow patterns in the fetal lamb in utero. In: Proceedings of the Sir Joseph Barcroft Symposium: Foetal and Neonatal Physiology. Cambridge, UK: Cambridge Univ. Press, 1990, p. 129-135.
22. Kontos, H. A., and E. P. Wei. Hydroxyl radical dependent inactivation of guanylate cyclase in cerebral arterioles by methylene blue and by LY 83583. Stroke 24: 427-434, 1993.
23. Kovalcik, V. The response of the isolated ductus arteriosus to oxygen and anoxia, Br. J. Physiol. 169: 185-197, 1963.
24. Levin, D. L., A. I. Hymann, M. A. Heymann, and A. M. Rudolph. Fetal hypertension and the development of increased pulmonary vascular smooth muscle, a possible mechanism for persistent pulmonary hypertension of the newborn infant. J. Pediatr. 92: 265-269, 1978.
25. Levin, D. L., L. J. Mills, M. Parkey, J. Garriot, and W. Cambell. Constriction of the fetal ductus arteriosus after administration of indomethacin to the pregnant ewe. J. Pediatr. 94: 647-650, 1979.
26. Lewis, A. B., M. A. Heymann, and A. ML Rudolph. Gestational age changes in pulmonary vascular responses in fetal lambs in utero. Circ. Res. 39: 536-541, 1976.
27. Mayer, B., F. Brunner, and K. Schmidt. Novel actions of methylene blue. Eur. Heart J. 14: 22-26, 1993.
28. Morin, F. C. I. Ligating the ductus arteriosus before birth causes persistent pulmonary hypertension in the newborn lamb. Pediatr. Res. 25: 251-257, 1989.
29. Morita, T., M. A. Perrella, M. E. Lee, and S. Kourembanas. Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc. Natl. Acad. Sci. 92:1475-1479, 1995.
30. Nakanishi, T., H. Gu, N. Hagiwara, and K. Momma. Mechanisms of oxygen-induced contraction of ductus arteriosus isolated from the fetal rabbit. Circ. Res. 72: 1218-1228, 1993.
31. 2 synthesis in isolated dog renal arteries. J. Pharmacol. Exp. Ther. 254: 198-203, 1990.
32. Pollock, J. S., M. Nakane, L. D. K. Buttery, A. Martinez, D. Springall, J. M. Polak, U. Forstermann, and F. Murad, Characterization and localization of endothelial nitric oxide synthase using specific monoclonal antibodies. Am. J. Physiol. 265 (Cell Physiol. 34): C1379-C1387, 1993.
33. Rengasamy, A., and R. A. Johns. Characterization of endothelium-derived relaxing factor/nitric oxide synthase from bovine cerebellum and mechanism of modulation by high and low oxygen tensions. J. Pharmacol. Exp. Ther. 259: 310-316, 1991.
34. Shaul, P. W., M. A. Farrar, and T. M. Zellers. Oxygen modulates endothelium-derived relaxing factor production in fetal pulmonary arteries. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H355-H364, 1992.
35. Suematsu, M., N. Goda, T. Sano, S. Kashiwagi, T. Egawa, Y. Shinoda, and Y. Ishimura. Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver. J. Clin. Invest. 96: 2431-2437, 1995.
36. Tannenbaum, J. E., N. S. Waleh, F. Mauray, L. Gold, E. A. Perkett, and R. I. Clyman. Transforming growth factor-β protein and messenger RNA expression is increased in the closing ductus arteriosus. Pediatr. Res 39: 427-434, 1996.
37. Tiktinsky, M. H., and F. C. Morin. Increasing oxygen tension dilates fetal pulmonary circulation via endothelium-derived relaxing factor. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H376-H380, 1993.
38. Toda, T., N. Tsuda, T. Takagi, I. Nishimori, D. Leszezynski, and F. Kummerow. Ultrastructure of developing human ductus aerteriosus. J. Anat. 131: 35-37, 1980.
39. Utz, J., and V. Ullrich. Carbon monoxide relaxes ileal smooth muscle through activation of guanylate eyclase. Biochem. Pharmacol. 41: 1195-1201, 1991.
40. Wolin, M. S., P. D. Cherry, J. M. Rodenburg, E. J. Messina, and G. Kaley. Methylene blue inhibits vasodilation of skeletal muscle arterioles to acetycholine and nitric oxide via the extracellular generation of Superoxide anion. J. Pharmacol. Exp. Ther. 254: 872-876, 1990.
41. Yoder, M. J., F. G. Banmann, N. M. Grover-Johnson, I. Brick, and A. M. Imparato. A morphological study of early cellular changes in the closure of the rabbit ductus arteriosus. Anat. Rec. 192: 19-40, 1978.