Retroviruses in autoimmune liver disease: Genetic or environmental agents?

Archivum Immunologiae et Therapiae Experimentalis

Volumn 47, Issue 5, 1999, Pages 289-297

  Mason, Andrew L ^a   Xu, Lizhe ^a   Guo, Linsheng ^a   Garry, Robert F ^b  

^a OCHSNER MEDICAL CENTER   (United States)

^b TULANE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Autoimmune liver disease; Hepatitis c virus; Human endogenous retroviruses; Human intracisterial a type particle; Primary biliary cirrhosis; Sj gren's syndrome; Systemic lupus erythematosus

Indexed keywords

EPITOPE; GAG PROTEIN;

AMINO ACID SEQUENCE; AUTOIMMUNE DISEASE; BILIARY CIRRHOSIS; COMPARATIVE STUDY; CROSS REACTION; DEFECTIVE VIRUS; GENE EXPRESSION REGULATION; GENETICS; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN T CELL LEUKEMIA VIRUS 1; IMMUNOLOGY; ISOLATION AND PURIFICATION; LIVER DISEASE; MOLECULAR GENETICS; MOLECULAR MIMICRY; ONCOGENE; PATHOGENICITY; RETROVIRUS; RETROVIRUS INFECTION; REVIEW; SALIVARY GLAND; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS; VIROLOGY;

AMINO ACID SEQUENCE; AUTOIMMUNE DISEASES; CROSS REACTIONS; DEFECTIVE VIRUSES; GENE EXPRESSION REGULATION, VIRAL; GENES, INTRACISTERNAL A-PARTICLE; HEPACIVIRUS; HEPATITIS B VIRUS; HEPATITIS C, CHRONIC; HIV; HIV CORE PROTEIN P24; HIV INFECTIONS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; IMMUNODOMINANT EPITOPES; LIVER CIRRHOSIS, BILIARY; LIVER DISEASES; LUPUS ERYTHEMATOSUS, SYSTEMIC; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; RETROVIRIDAE; RETROVIRIDAE INFECTIONS; SALIVARY GLANDS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SJOGREN'S SYNDROME;

EID: 0033256573     PISSN: 0004069X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. ACHA-ORBEA H. and PALMER E. (1991): MIs - a retrovirus exploits the immune system. Immunol. Today, 12, 356-361.
2. ALARCON-SEGOVIA D., DIAZ-JOUANEN E. and FISHBEIN E. (1973): Features of Sjögren's syndrome in primary biliary cirrhosis. Ann. Intern. Med., 79, 31.
3. BOLLER K., JANSSEN O., SCHULDES H., TONJES R. and KURTH R. (1997): Characterization of antibody response specific for the human endogenous retrovirus HTDV/HERV-K. J. Virol., 71, 4581-4588.
4. BOYD M. T., FOLEY B. and BRODSKY I. (1997): Evidence for copurification of HERV-K-related transcripts and a reverse transcriptase activity in human platelets from patients with essential thrombocythemia. Blood, 90, 4022-4030.
5. CHU J. L., DRAPPA J., PARNASSA A. and ELKON K. B. (1993): The defect in Fas mRNA expression in MRL/Ipr mice is associated with insertion of the retrotransposon, ETn. J. Exp. Med., 178, 723-730.
6. CONRAD B., WEIDMAN E., TRUCCO G., RUDERT W. A., BEHBOO R., RICORDI R. et al. (1994): Evidence of superantigen involvement in insulin-dependant diabetes mellitus aetiology. Nature, 371, 351-355.
7. CONRAD B., WEISSMAHR R. N., BONI J., ARCARI R., SCHUPBACH J. and MACH B. (1997): A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes. Cell, 90, 303-313.
8. DANGEL A. W., MENDOZA A. R., BAKER B. J., DANIEL C. M., CARROLL M. C., WU L. C. et al. (1994): The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among old world primates. Immunogenetics, 40, 425-436.
9. DEAS J. E., LIU L. G., THOMPSON J. J., SANDER D. M., SOBLE S. S., GARRY R. F. et al. (1998): Reactivity of sera from systemic lupus erythematosus and Sjögren's syndrome patients with peptides derived from human immunodeficiency virus p24 capsid antigen. Clin. Diagn. Lab. Immunol., 5, 181-185.
10. DOHERTY D. G., UNDERHILL J. A., DONALDSON P. T., MANABE K., MIELI-VERGANI G., EDDLESTON A. L. et al. (1994): Polymorphism in the human complement C4 genes and genetic susceptibility to autoimmune hepatitis. Autoimmunity, 18, 243-249.
11. GARRY R. F., FERMIN C. D., HART D. J., ALEXANDER S. S., DONEHOWER L. A. and LUO-ZHANG H. (1990): Detection of a human intracisternal A-type retroviral particle antigenically related to HIV. Science, 250, 1127-1129.
12. + T lymphopenia patients. AIDS Res. Hum. Retroviruses, 12, 931-940.
13. GARRY R. F., KRIEG A. M., CHEEVERS W. P., MONTELARO R. C., GOLDING H., FERMIN C. D. et al. (1995): Retroviruses and their role in chronic inflammatory diseases and autoimmunity. In LEVY J. (ed.): Retroviridae. Plenum Press, New York, 4, 491-602.
14. GASKINS H. R., PROCHAZKA M., HAMAGUCHI K., SERREZE D. V. and LEITER E. H. (1992): Beta cell expression of endogenous xenotropic retrovirus distinguishes diabetes-susceptible NOD/Lt from resistant NON/Lt mice. J. Clin. Invest., 90, 2220-2227.
15. GOLDING P. L., SMITH M. and WILLIAMS R. (1973): Multisystem involvement in chronic liver disease. Studies on the incidence and pathogenesis. Am. J. Med., 55, 772.
16. HADDAD J., DENY P., MUNZ GOTHEIL C., AMBROSINI J. C., TRINCHET J. C., PATERON D. et al. (1992): Lymphocytic sialadenitis of Sjögren's syndrome associated with chronic hepatitis C virus liver disease. Lancet, 339, 321-323.
17. IZUI S., MCCONAHEY P. J., THEOFILOPOULOS A. N. and DIXON F. J. (1979): Association of circulating retroviral gp70-anti-gp70 immune complexes with murine systemic lupus erythematosus. J. Exp. Med., 149, 1099-1116.
18. JASPAN J. B., SULLIVAN K., CARRY R. F., LOPEZ M., WOLFE M., CLEJAN S. et al. (1996): The interaction of a type-A retroviral particle and class II human leukocyte antigen susceptibility genes in the pathogenesis of Graves' disease. J. Clin. Endocrinol. Metab., 81, 2271-2279.
19. JOPLIN R., LINDSAY J. G., JOHNSON G. D., STRAIN A. and NEUBERGER J. (1992): Membrane dihydrolipoamide actyltransferase (E2) on human biliary epithelial cells in primary biliary cirrhosis. Lancet, 339, 93-94.
20. KRAMER A., KEITEL T., WINKLER K., STOCKLEIN W., HOHNE W. and SCHNEIDER-MERGENER J. (1997): Molecular basis for the binding promiscuity of an anti-p24 (HIV-1) monoclonal antibody. Cell, 91, 799-809.
21. KING P. D., MCMURRAY R. W. and BECHERER P. R. (1994): Sjögren's syndrome without mixed cryoglobulinemia is not associated with hepatitis C virus infection. Am. J. Gastroenterol., 89, 1047-1050.
22. KOIKE K., MORIYA K., ISHIBASHI K., YOTSUYANAGI H., SHINTANI Y., FUJIE H. et al. (1997): Sialadenitis histologically resembling Sjögren's syndrome in mice transgenic for hepatitis C virus envelope genes. Proc. Natl. Acad. Sci. USA, 94, 233-236.
23. LAN M. S., MASON A., CHEN Q. Y., VARGAS A., RAO J., GOMEZ R. et al. (1998): HERV-K10s and immune-mediated (tye 1) diabetes. Cell, 95, 14-16.
24. MANNS M. P., BREMM A., SCHNEIDER P. M., NOTGHI A., GERKEN G., PRAGER-EERBELE M. et al. (1991): HLA DRw8 and complement C4 deficiency as risk factors in primary biliary cirrhosis. Gastroenterology, 101, 1367-1373.
25. MARCELLIN P. and BENHAMOU J. P. (1995): Autoimmune disorders associated with hepatitis C. Prog. Liver Dis., 13, 247-267.
26. MASON A. L. and PERRILLO R. P. (1996): The A to Z of new hepatotrophic agents. Liber Transplant. Surg., 2, 395-405.
27. MASON A., XU L., GUO L., MUNOZ S., JASPEN J. B., BRYER-ASH M. et al. (1998): Detection of retroviral antibodies in primary biliary cirrhosis and other idiopathic biliary disorders. Lancet. 351, 1620-1624.
28. MICHEL G., RITTER A., GERKEN G., MEYER ZUM BUSCHENFELDE K. H., DECKER R. and MANNS M. P. (1992): Anti-GOR and hepatitis C virus in autoimmune liver diseases. Lancet, 339, 267-269.
29. MILLER R. H. and ROBINSON W. S. (1986): Common evolutionary origin of hepatitis B virus and retroviruses. Proc. Natl. Acad. Sci. USA, 83, 2531-2535.
30. MISHIRO S., HOSHI Y., TAKEDA K., YOSHIKAWA A., GOTANDA T., TAKAHASHI K. et al. (1990): Non-A, non-B hepatitis specific antibodies directed at host-derived epitope: implication for an autoimmune process. Lancet, 336, 1400-1402.
31. MISHIRO S., TAKEDA K., HOSHI Y., YOSHIKAWA A., GOTANDA T. and ITOH Y. (1991): An autoantibody cross-reactive to hepatitis C virus core and a host nuclear antigen. Autoimmunity, 10, 269-273.
32. NAKAGAWA K. and HARRISON L. C. (1996): The potential roles of endogenous retroviruses in autoimmunity. Immunol. Rev., 152, 193-236.
33. NEUBERGER J. (1997): Primary biliary cirrhosis. Lancet, 350, 875-879.
34. NEUBERGER J. M., PORTMANN B., MACDOUGALL B., CALNE R. and WILLIAMS R. (1982): Recurrence of primary biliary cirrhosis after liver transplantation. N. Engl. J. Med., 306, 1-4.
35. PAWLOTSKY J. M., YAHIA M. B., ADRE C., VOISIN M. C., INTRATOR L., ROUDOT-THORAVAL F. et al. (1994): Immunological disorders in C virus chronic active hepatitis: a prospective case-control study. Hepatology, 19, 841-848.
36. PERRON H., GARSON J. A., BEDIN F., BESEME F., PARANHOS-BACCALA G., KOMARIAN-PRADEL F. et al. (1997): Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The collaborative research group on multiple sclerosis. Proc. Natl. Acad. Sci. USA, 94, 7583-7588.
37. PIRISI M., SCOTT C., FABRIS C, FERRACCIOLI G., SOARDO G., RICCI R. et al. (1994): Mild sialadenitis: a common finding in patients with hepatitis C virus infection. Scand. J. Gastroenterol., 29, 942.
38. RODRIGUEZ-CUARTERO A., GARCIA-VERA E. and GOMEZ-CERRO A. (1994): Hepatitis C virus and Sjögren's syndrome. Infection, 22, 415-416.
39. SADAMOTO T., JOPLIN R., KEOGH A., MASON A., CARMAN W. and NEUBERGER J. (1998): Expression of pyruvate dehydrogenase complex PDC-E2 on biliary epithelial cells induced by lymph nodes from primary biliary cirrhosis. Lancet, 352, 1595-1596.
40. TALAL N., DAUPHINEE M., DANG H., ALEXANDER S., HART D. and GARRY R. (1990): Detection of serum antibodies to retroviral proteins in patients with Sjögren's syndrome. Arthritis Rheum., 33, 741-781.
41. TALAL N., GARRY R., ALEXANDER S., DAUPHINEE M., BALLESTER A., TEKEI M. et al. (1990): A conserved idiotype and antibodies to retroviral proteins in systemic lupus erythematosus. J. Clin. Invest., 85, 1866-1871.
42. TRIGGER D. R. (1980): Primary biliary cirrhosis: an epidemiological study. Br. Med. J., 281, 772-775.
43. TSUNEYAMA K., VAN-DE-WATER J., NAKANUMA Y., CHA S., ANSARI A., COPPEL R. et al. (1994): Human combinatorial autoantibodies and mouse monoclonal antibodies to PDC-E2 produce abnormal apical staining of salivary glands in patients with co-existing primary biliary cirrhosis and Sjögren's syndrome. Hepatology, 20, 893-898.
44. VAN-DE-WATER J., COOPER A., SURH C. D., COPPEL R., DANNER D., ANSARI A. et al. (1989): Detection of autoantibodies to the recombinant 74 Kd and 52 Kd mitochondrial autoantigens of primary biliary cirrhosis. N. Engl. J. Med., 320, 1377-1380.
45. VAN-DE-WATER J., GERSON L. B., FERRELL L. D., LAKE J. R., COPPEL R. L., BATTS K. P. et al. (1996): Immunohistochemical evidence of disease recurrence following liver transplantation for primary biliary cirrhosis. Hepatology, 24, 1079-1084.
46. VAN GENT D. C., MIZUUCHI K. and GELLERT M. (1996): Similarities between initiation of V (D) J recombination and retroviral integration. Science, 271, 1592-1594.
47. WILKINSON D. A., MAGER D. L. and LEONG J. C. (1994): Endogenous human retroviruses. In LEVY J. (ed.): Retroviridae, Plenum Press, New York, 3, 465-535.
48. WU J., ZHOU T. HE J. and MOUNTZ J. D. (1993): Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene. J. Exp. Med., 178, 461-468.
49. XU L., GUO L., JOPLIN R., NEUBERGER J., RIXON F., AITKIN J., et al. (1997): Viral induction of primary biliary cirrhosis (abstract). J. Hepatol., 26, 61.