Diagnostic molecular pathology comes of age

Advances in Anatomic Pathology

Volumn 6, Issue 6, 1999, Pages 324-326

  El Naggar, Adel K ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Chromosomal translocations; Fusion transcript; Genetic markers; Molecular diagnosis

Indexed keywords

DNA BINDING PROTEIN; NEUROTROPHIN 3 RECEPTOR; ONCOPROTEIN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS; TRANSCRIPTION FACTOR ETV6;

ARTICLE; CHROMOSOME 12; CHROMOSOME 15; DIFFERENTIAL DIAGNOSIS; FEMALE; GENE FUSION; GENE TRANSLOCATION; GENETICS; HUMAN; INFANT; KARYOTYPING; KIDNEY TUMOR; MALE; MESOBLASTIC NEPHROMA; NEWBORN; PATHOLOGY;

ARTIFICIAL GENE FUSION; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 15; DIAGNOSIS, DIFFERENTIAL; DNA-BINDING PROTEINS; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; KARYOTYPING; KIDNEY NEOPLASMS; MALE; NEPHROMA, MESOBLASTIC; ONCOGENE PROTEINS, FUSION; PROTO-ONCOGENE PROTEINS C-ETS; RECEPTOR, TRKC; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC;

EID: 0033227247     PISSN: 10724109     EISSN: 15334031     Source Type: Journal    
DOI: 10.1097/00125480-199911000-00003     Document Type: Note

References (17)

1. Cooper CS. Translocations in solid tumors. Curr Opin Genet Dev 1996;6:71-5.
2. Burchill SA, Wheeldon J, Cullinance C, Lewis IJ. EWS-FLTI fusion transcripts identified in patients with typical neuroblastoma. Eur J Cancer 1997;33:239-43.
3. Edwards RH, Chatten J, Xiong Q-B, Barr FG. Detection of gene fusion in rhabdomyosarcoma by reverse transcriptase-polymerase chain reaction assay of archival samples. Diag Mol Pathol 1997; 6:91-7. (Pubitemid 27155029)
4. Tsuji S, Hisaoka M, Morimitsu Y, et al. Detection of SYT-SSX fusion transcripts in synovial sarcoma by reverse transcriptionpolymerase chain reaction using archival paraffin-embedded tissues. Am J Pathol 1998;153:1807-12. (Pubitemid 28550668)
5. Rabbitts TH. Perspective: chromosomal translocations can affect genes controlling gene expression and differentiation - why are these functions targeted? J Pathol 1999;187:39-42. (Pubitemid 29009834)
6. Inagaki H, Murase T, Otsuka T, Eimoto T. Detection of SYT-SSX fusion transcript in synovial sarcoma using archival cytologic specimens. Am J Clin Pathol 1999;111:528-33. (Pubitemid 29153150)
7. Argule JC, Tomlinson GE, Stewart D, Schneider NR. Ultrastruc-tural, immunocytochemical and cytogenetic characterization of a large congenital fibrosarcoma. Arch Pathol Lab Med 1992;116: 972-5.
8. Fidelia-Lambert MN, Zhuang Z, Tsokos M. Sensitive detection of rare Ewing's sarcoma cells in peripheral blood by reverse transcriptase polymerase chain reaction. Hum Pathol 1999;30:78-80. (Pubitemid 29037398)
9. Safar A, Wickert R, Nelson M, Neff JR, Bridge JA. Characterization of a variant SYT-SSXI synovial sarcoma fusion transcript. Diag Mol Pathol 1998;7:283-7. (Pubitemid 29156106)
10. Rubin BP, Chen C-J, Morgan TW, et al. Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion. Cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma. Am J Pathol 1998;153:1451-8. (Pubitemid 28509901)
11. Burchill SA, Lewis IJ, Selby P. Improved methods using the reverse transcriptase polymerase chain reaction to detect tumor cells. Br J Cancer 1999;79:971-7. (Pubitemid 29082135)
12. Fujita J, Ueda Y, Bandoh S, Namihira H, Ishii T, Takahara J. A case of leptomeningeal metastasis from lung adenocarcinoma di-agnosed by reverse transcriptase polymerase chain reaction for carcinoembryonic antigen. Lung Cancer 1998;22:153-6. (Pubitemid 29050857)
13. Datta YH, Adams PT, Drobyski WR, Ethier SP, Terry VH, Roth MS. Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction. J Clin Oncol 1994;12: 475-82. (Pubitemid 24079887)
14. Hattinger CM, Rumpler S, Strehl S, et al. Prognostic impact of deletions at lp36 and numerical aberrations in Ewing tumors. Genes, Chromosomes Cancer 1999;24:243-54. (Pubitemid 29070164)
15. Lin PP, Brody RI, Hamelin AC, Bradner JE, Healey JH, Ladanyi M. Differential transactivation by alternative EWS-FLIl fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma. Cancer Res 1999;59:1428-32. (Pubitemid 29160104)
16. Kurian KM, Waston CJ, Wyllie AH. DNA OHIP technology. J Pathol 1999;187:267-71.
17. Brown PO, Botstein D. Exploring the new world of the genome with DNA microarrays. Nature Genet 1999;21(suppl):33-7. (Pubitemid 29031489)