Telomerase activity and in situ telomerase RNA expression in oral carcinogenesis

Journal of Oral Pathology and Medicine

Volumn 28, Issue 9, 1999, Pages 389-396

  Chang, Lien Yu ^a   Lin, Shu Chun ^a   Chang, Che Shoa ^a,b   Wong, Yong Kie ^a,c   Hu, Yueh Chiang ^a   Chang, Kuo Wei ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

hTR; In situ hybridization; Oral squamous cell carcinoma; Telomerase activity; TRAP

Indexed keywords

CARCINOGENESIS; MITOSIS; RNA EXPRESSION; TELOMERASE;

EID: 0033213081     PISSN: 09042512     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0714.1999.tb02109.x     Document Type: Article

References (34)

1. LANDSDORP PM. Lessons from mice without telomerase. J Cell Biol 1997; 139: 309-12.
2. HARLEY CB. Telomere loss: mitotic clock or genetic time bomb? Mutat Res 1991; 256: 271-82.
3. AUTEXIER C, GREIDER CW. Telomerase and cancer: revisiting the telomere hypothesis. Trends Biochem Sci 1996; 21: 387-91.
4. SHAY JW, GAZDAR AF. Telomerase in the early detection of cancer. J Clin Pathol 1997; 50: 106-9.
5. COUNTER CM, AVILION AA, LEFEUVRE CE, et al. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 1992; 11: 1921-9.
6. GREIDER CW, BLACKBURN EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985; 43: 405-13.
7. YU GL, BRADLEY JD, ATTARDI LD, BLACKBURN EH. In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs. Nature 1990; 344: 126-31.
8. FENG J, FUNK WD, WANG SS, et al. The RNA component of human telomerase. Science 1995; 169: 1236-41.
9. NAKAMURA TM, MORIN GB, CHAPMAN KB, et al. Telomerase catalytic subunit homologs from fission yeast and human. Science 1997; 277: 955-9.
10. MEYERSON M, COUNTER CM, EATON EN, et al. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 1997; 90: 785-95.
11. RENAN MJ. How many mutations are required for tumorigenesis? Implications from human cancer data. Mol Carcinog 1993; 7: 139-46.
12. KIM NW, PIATYSZEK MA, PROWSE KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266: 2011-5.
13. CALIFANO J, AHRENDT SA, MEININGER G, WESTRA WH, KOCH WM, SIDRANSKY, D. Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients. Cancer Res 1996; 56: 5720-2.
14. MUTIRANGURA A, SUPIYAPHUN P, TRIREKAPAN S, et al. Telomerase activity in oral leukoplakia and head and neck squamous cell carcinoma. Cancer Res 1996; 56: 3530-3.
15. MAO L, EL-NAGGAR AK, FAN Y-H, et al. Telomerase activity in head and neck squamous cell carcinoma and adjacent tissues. Cancer Res 1996; 56: 5600-4.
16. KANNAN S, TAHARA H, YOKOZAKI H, et al. Telomerase activity in premalignant and malignant lesions of human oral mucosa. Cancer Epidem Biol Prev 1997; 6: 413-20.
17. SUMIDA T, SOGAWA K, HAMAKAWA H, et al. Detection of telomerase activity in oral lesions. J Oral Pathol Med 1998; 27: 111-5.
18. SUMIDA T, HAMAKAWA H, SOGAWA K, et al. Telomerase components as a diagnostic tool in human oral lesions. Int J Cancer 1999; 80: 1-4.
19. SLAUGHTER DP, SOUTHWICK HW, SMEJKAL W, et al. "Field cancerization" in oral stratified squamous epithelium: clinical implications of multicentric origin. Cancer 1953; 6: 963-8.
20. WONG DY, CHANG KW, CHEN CF, CHANG RC. Characterization of two new cell lines derived from oral cavity human squamous cell carcinoma - OC1 and OC2. J Oral-Maxillofac Surg 1990; 48: 385-90.
21. SILVERMAN S, GORSKY M, LOZADA F. Oral leukoplakia and malignant transformation: a follow-up study of 257 patients. Cancer 1984; 53: 563-8.
22. CALIFANO J, VAN DER RIET P, WESTRA W, et al. Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res 1996; 56: 2488-92.
23. AVILION AA, PIATYSZEK MA, CUPTA J, SHAY JW, BACCHETTI S, GREIDER CW. Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. Cancer Res 1996; 56: 645-50.
24. SODER AI, HOARE SF, MUIR S, GOING JJ, PARKINSON KE, KEITH NW. Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer. Oncogene 1997; 14: 1013-21.
25. YASHIMA K, LITZKY LA, KAISER L, et al. Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung cancer. Cancer Res 1997; 57: 2373-7.
26. YASHIMA K, ASHFAG R, NOWAK J, et al. Telomerase activity and expression of its RNA component in cervical lesions. Cancer 1998; 82: 1319-27.
27. SODER AI, GOING JJ, KAYF SB, NICOL KW. Tumor specific regulation of telomerase RNA gene expression visualized by in situ hybridization. Oncogene 1998; 16: 979-83.
28. YASHIMA K, PIATYSZEK MA, SABOORIAN HM, et al. Telomerase activity and in situ telomerase RNA expression in malignant and non-malignant lymph nodes. J Clin Pathol 1997; 50: 110-7.
29. OGOSHI M, LE T, SHAY JW, TAYLOR RS. In situ hybridization analysis of the expression of human telomerase RNA in normal and pathologic conditions of the skin. J Invest Dermatol 1998; 110: 818-23.
30. CHANG KW, LACONI S, MANGOLD KA, HUBCHAK S, SCARPELLI DG. Multiple genetic alterations in hamster pancreatic adenocarcinomas. Cancer Res 1995; 55: 2560-8.
31. HIYAMA E, HIYAMA K, YAMAOKA H, ICHIKAWA T, SHAY JW, YOKOYAMA T. Telomerase activity in neuroblastoma; is it a prognostic indicator of clinical behavior? Eur J Cancer 1997; 33: 1932-6.
32. 35S- and digoxigenin-labeled RNA and oligonucleotide probes for in situ hybridization. Expression of mRNA of the seminal vesicle secretion protein II and androgen receptor genes in the prostate. Histochemistry 1992; 98: 217-8.
33. PEDERSON J. The plurifunctional nucleolus. Nucleic Acids Res 1998; 26: 3871-6.
34. GREIDER CW. Telomerase activity, cell proliferation and cancer. Proc Natl Acad Sci USA 1998; 95: 90-2.