Expression of the steroid receptor RNA activator in human breast tumors

Cancer Research

Volumn 59, Issue 17, 1999, Pages 4190-4193

  Leygue, Etienne ^a   Dotzlaw, Helmut ^a   Watson, Peter H ^a   Murphy, Leigh C ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; STEROID RECEPTOR RNA ACTIVATOR; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOMA; CONTROLLED STUDY; HORMONE RESISTANCE; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BREAST NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 5; FEMALE; HISTONE ACETYLTRANSFERASES; HUMANS; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; RECEPTORS, STEROID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0033198372     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Vorherr, H. (ed.). Breast Cancer. Baltimore: Urban and Schwarzenberg Press, 1980.
2. Jordan, V. C., and Morrow, M. Tamoxifen, Raloxifene, and the prevention of breast cancer. Endocr. Rev., 20: 253-278, 1999.
3. Green, S., Walter, P., Kumar, V., Krust, A., Bornert, J. M., Argos, P., and Chambon. P. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature (Lond.), 320: 134-139, 1986.
4. Mosselman, S., Polman, J., and Dijkema, R. ER β: identification and characterization of a novel human estrogen receptor. FEBS Lett., 392: 49-53, 1996.
5. Ogawa, S., Inoue, S., Watanabe, T., Hiroi, H., Orimo, A., Hosoi, T., Ouchi, Y., and Muramatsu, M. The complete primary structure of human estrogen receptor β (hER β) and its heterodimerization with ER a in vivo and in vitro. Biochem. Biophys. Res. Commun., 243: 129-132, 1998.
6. Evans, R. M. The steroid and thyroid receptor super-family. Science (Washington DC), 240: 889-895, 1988.
7. Shibata, H., Spencer, T. E., Onate, S. A., Jenster, G., Tsai, S. Y., Tsai, M. J., and O'Malley, B. W. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Rec. Prog. Horm. Res., 52: 141-164, 1997.
8. McKenna, N. J., Lanz, R. B., and O'Malley, B. W. Nuclear receptor coregulators: cellular and molecular biology. Endocr. Rev , 20: 321-344, 1999.
9. Lanz, R. B., McKenna, N. J., Onate, S. A., Albrecht, U., Wong, J., Tsai, S. Y., Tsai, M-J., and O'Malley, B. W. A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell, 97: 17-27, 1999.
10. Henderson, I. C., and Patek, A. J. The relationship between prognostic and predictive factors in the management of breast cancer. Breast Cancer Res. Treat., 52: 261-288, 1998.
11. Elston, C. W., and Ellis, I. O. Pathological prognostic factors in breast cancer. Histopathology, 19: 403-410, 1991.
12. Leygue, E., Murphy, L. C., Kuttenn, F., and Watson, P. H. Triple primer PCR: a new way to quantify truncated mRNA expression. Am. J. Pathol., 148: 1097-1103, 1996.
13. Leygue, E., Watson, P. H., and Murphy, L. C. Estrogen receptor variants in normal human mammary tissue. J. Natl. Cancer Inst., 88: 284-290, 1996.
14. Daffada, A. A. I., Johnston, S. R. D., Nicholls, J., and Dowsett, M. Detection of wild type and exon 5-deleted splice variant oestrogen receptor (ER) mRNA in ER-positive and -negative breast cancer cell lines by reverse transcription/polymerase chain reaction. J. Mol. Endocrinol., 13: 265-273, 1994.
15. Anzick, S. L., Kononen, J., Walker, R. L., Azorsa. D. O., Tanner, M. M., Guan, X. Y., Sauter, G., Kallioniemi, O. P., Trent, J. M., and Meltzer, P. S. A1B1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science (Washington DC), 277: 965-968, 1997.
16. Bautista, S., Valles, H., Walker, R. L., Anzick, S., Zeillinger, R., Meltzer, P., and Theillet, C. In breast cancer, amplification of the steroid receptor coactivator gene A1B1 is correlated with estrogen and progesterone receptor positivity. Clin. Cancer Res., 4: 2925-2929, 1998.
17. Read, L., Greene, G., and Katzenellenbogen, B. Regulation of estrogen receptor messenger ribonucleic acid and protein levels in human breast cancer cell lines by sex steroid hormones, their antagonists and growth factors. Mol. Endocrinol., 3: 295-304, 1989.
18. Berkenstam, A., Glaumann, H., Martin, M., Gustafsson, J. A., and Norstedt, G. Hormonal regulation of estrogen receptor messenger ribonucleic acid in T47Dco and MCF-7 breast cancer cells. Mol. Endocrinol., 3: 22-28, 1989.
19. Berry, M., Metzger. D., and Chambon, P. Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J., 9: 2811-2818, 1990.
20. Osborne, C. K. Steroid hormone receptors in breast cancer management. Breast Cancer Res. Treat., 51: 227-238, 1998.
21. Berns, E. M., Van Staveren, I. L., Klijn, J. G., and Foekens, J. A. Predictive value of SRC-1 for tamoxifen response of recurrent breast cancer. Breast Cancer Res. Treat., 48: 87-92, 1998.
22. Hermsen, M. A., Baak, J. P., Meijer, G. A., Weiss, J. M., Walboomers, J. W., Snijders, P. J., and van Diest, P. J. Genetic analysis of 53 lymph node-negative breast carcinomas by CGH and relation to clinical, pathological, morphometric, and DNA cytometric prognostic factors. J. Pathol., 186: 356-362, 1998.
23. Schwendel, A., Richard, F., Langreck, H., Kaufmann, O., Lage, H., Winzer, K. J., Petersen, I., and Dietel, M. Chromosome alterations in breast carcinomas: frequent involvement of DNA losses including chromosomes 4q and 21q. Br. J. Cancer, 78: 806-811, 1998.
24. Tirkkonen, M., Johannsson, O., Agnarsson, B. A., Olsson, H., Ingvarsson, S., Karhu, R., Tanner, M., Isola, J., Barkardottir, R. B., Borg, A., and Kallioniemi, O. P. Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations. Cancer Res., 57: 1222-1227, 1997.