The development of and perspectives for genetic engineering of malaria parasites

Parassitologia

Volumn 41, Issue 1-3, 1999, Pages 453-459

  Waters, A P ^a   Janse, C J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Genetic engineering; Malaria; Plasmodium; Review; Transfection

Indexed keywords

PROTOZOAL DNA; RECOMBINANT DNA;

ANIMAL; CHEMISTRY; GENETIC ENGINEERING; GENETIC TRANSFECTION; GENETICS; HUMAN; MALARIA; PARASITOLOGY; PLASMODIUM; REVIEW; TRANSGENE;

ANIMALS; DNA, PROTOZOAN; DNA, RECOMBINANT; GENETIC ENGINEERING; HUMANS; MALARIA; PLASMODIUM; TRANSFECTION; TRANSGENES;

EID: 0033182503     PISSN: 00482951     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Biebinger S, Wirtz LE, Lorenz P, Clayton C (1997) Vectors for inducible expression of toxic gene products in bloodstream and procyclic Trypanosoma brucei Mol Biochem Parasitol 85: 99-112
2. Crabb BS, Cooke BM, Reeder JC, Waller RF, Caruana, SR, Davern KM, Wickham ME, Brown GV, Coppel RL, Cowman AF (1997) Targeted gene disruption shows that knobs enable malaria-infected red cells to cytoadhere under physiological shear stress. Cell 89: 287-296
3. Crabb BS, Cowman AF (1996) Characterization of promoters and stable transfection by homologous and nonhomologous recombination in Plasmodium falciparum. Proc Natl Acad Sci USA 93: 7289-7294.
4. Crabb BS, Triglia T, Waterkeyn JG, Cowman AF (1997). Stable transgene expression in Plasmodium falciparum Mol Biochem Parasitol 90: 131-144
5. de Koning-Ward TF, Thomas AW, Waters AP, Janse CJ (1998). Stable, drug-selected expression of Green Fluorescent Protein in Plasmodium berghei. Mol Biochem Parasitol 97 247-252.
6. Donald RGK, Roos DS (1993) Stable molecular transformation of Toxoplasma gondii a selectable dihydrofolate reductase-thymidylate synthase marker based on drug-resistance mutations tn malaria. Proc Natl Acad Sci USA 90: 11703-11707.
7. Donald RG, Roos DS (1994) Homologous recombination and gene replacement at the dihydrofolate reductase-thymidylate synthase locus in Toxoplasma gondii. Mol Biochem Parasitol 63 243-253
8. Fidock DA, Wellems TE (1997). Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil. Proc Natl Acad Sci USA 94: 10931-10936.
9. Gardner MJ, Tettelin H, Carucci DJ, Cummings LM, Aravind L, Koonin EV, Shallom S, Mason T, Yu K, Fujii C, Pederson J, Shen K, Jing J, Aston C, Lai Z, Schwartz DC, Pertea M, Salzberg S, Zhou L, Sutton GG, Clayton R, White O, Smith HO, Fraser CM, Adams MD, Venter JC, Hoffman SL (1998). Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum Science 282: 1126-1132.
10. Goonewardene R, Daily J, Kaslow D, Sullivan TJ, Duffy P, Carter R, Mendis K, Wirth D (1993). Transfection of the malaria parasite and expression of firefly luciferase. Proc Natl Acad Sci USA 90 5234-5236
11. Gossen M, Freundlieb S, Bender G, Müller G, Hillen W, Bujard H (1995) Transcriptional activation by tetracyclines in mammalian cells Science 268: 1766-1769.
12. Gueiros-Filho FJ, Beverley SM (1997) Trans-kingdom transposition of the Drosophila element mariner within the protozoan Leishmania Science 276 1716-1719
13. Horrocks P, Kilbey BJ (1996) Physical and functional mapping of the transcriptional start sites of Plasmodium falciparum proliferating cell nuclear antigen Mol Biochem Parasitol 82: 207-215
14. Kocken CHM, van der Wel AM, Dubbeld MA, Narum DL, van de Rijke FM, van Gemert G-J, van der Linde X, Bannister LH, Janse CJ, Waters AP, Thomas AW (1998). Precise timing of expression of a Plasmodium falciparum derived transgene in P berghei is a critical determinant of subsequent subcellular location J Biol Chem 273 15119-15124.
15. Margos G, van Dijk MR, Ramesar J, Janse CJ, Waters AP, Sinden RE (1998) Transgenic expression of a mosquito stage malarial protein, Pbs21, in blood stages of transformed Plasmodium berghei and the induction of an immune response upon infection Infect Immun 66 3884-3891
16. Ménard R, Sultan AA, Cortes C, Altszuler R, van Dijk MR, Janse CJ, Waters AP, Nussenzweig RS, Nussenzweig V (1997). Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes Nature 385: 336-340.
17. Ryan KA, Garraway LA, Descoteaux A, Turco SJ, Beverley SM (1993). Isolation of virulence genes directing surface glycosyl-phosphatidylinositol synthesis by functional complementation of Leishmania. Proc Natl Acad Sci USA 90: 8609-8613
18. Sultan AA, Thathy V, Frevert U, Robson KJH, Crisanti A, Nussenzweig V, Nussenzweig RS, Ménard R (1997). TRAP is necessary for gliding motility and infectivity of Plasmodium sporozoites. Cell 90: 511-522
19. Tomas AM, van der Wel AM, Thomas AW, Janse CJ, Waters AP (1998). Transfection systems for animal models of malaria Parasitol Today 14: 245-249.
20. Triglia T, Wang P, Sims PF, Hyde JE, Cowman AF (1998). Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria EMBO J 17: 3807-3815.
21. van der Wel AM, Tomas AM, Cocken CHM, Malhotra P, Janse CJ, Waters AP, Thomas AW (1997) Transfection and in vivo selection of the primate malaria parasite, Plasmodium knowlesi J Exp Med 185: 1499-1503
22. van Dijk MR, Janse CJ, Waters AP (1996) Expression of a Plasmodium gene introduced into subtelomeric regions of P. berghei chromosomes. Science 271: 662-665.
23. van Dijk MR, Waters AP, Janse CJ (1995). Stable transfection of malaria parasite blood stages. Science 268: 1358-1362.
24. Waters AP, van Dijk MR, Thomas AW, Janse CJ (1997). Transfection of malaria parasites. In: Methods' a companion to methods in enzymology - Analysis of apicomplexan parasites, 13: 134-147 Academic Press, New York, NY, USA.
25. Wirtz E, Clayton C (1995). Inducible gene expression in trypanosomes mediated by a prokaryotic repressor. Science 268: 1179-1183
26. Wu Y, Kirkman LA, Wellems TE (1996) Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine. Proc Natl Acad Sci USA 93: 1130-1134.
27. Wu Y, Sifri CD, Lei HH, Su XZ, Wellems TE (1995). Transfection of Plasmodium falciparum within human red blood cells. Proc Natl Acad Sci USA 92: 973-977.