An easter-like serine protease from Anopheles gambiae exhibits changes in transcript abundance following immune challenge

Insect Molecular Biology

Volumn 8, Issue 3, 1999, Pages 329-337

  Paskewitz, Susan M ^a   Reese Stardy, S ^a   Gorman, M J ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Anopheles gambiae; Malaria; Mosquito; Plasmodium; Prophenol oxidase activating enzyme; Serine protease

Indexed keywords

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CATECHOL OXIDASE; CHROMOSOME BANDING; DISEASE CARRIER; DISULFIDE BOND; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; GENE PRODUCT; GENETIC TRANSCRIPTION; IN SITU HYBRIDIZATION; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; SERINE PROTEINASE; SOUTHERN BLOTTING; TOBACCO HORN WORM;

AMINO ACID SEQUENCE; ANIMALS; ANOPHELES; BASE SEQUENCE; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CHROMOSOME MAPPING; CLONING, MOLECULAR; DNA, COMPLEMENTARY; FEMALE; INSECT PROTEINS; MOLECULAR SEQUENCE DATA; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES;

ANOPHELES GAMBIAE; DECAPODA (CRUSTACEA); DROSOPHILA MELANOGASTER; INSECTA; INVERTEBRATA; MANDUCA SEXTA; MELANOGASTER; MEROSTOMATA; NICOTIANA TABACUM; SERPENTES;

EID: 0033180316     PISSN: 09621075     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2583.1999.83124.x     Document Type: Article

References (28)

1. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. and Lipman, D.J. (1990) Basic local alignment search tool. J Mol Biol 215: 403-410.
2. Barillas-Mury, C., Charlesworth, A., Gross, I., Richman, A., Hoffmann, J.A. and Kafatos, F.C. (1996) Immune factor Gambif1, a new rel family member from the human malaria vector, Anopheles gambiae. EMBO J 15: 4961-4701.
3. Brown, T. (1995) Southern blotting. Current Protocols in Molecular Biology, USA (Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A. and Struhl, K., eds), pp. 2.9.1-2.9.15. John Wiley & Sons, New York.
4. Chun, J., Riehle, M. and Paskewitz, S.M. (1995) Effect of mosquito age and reproductive status on melanization of Sephadex beads in Plasmodium-refractory and susceptible strains of Anopheles gambiae. J Invertebrate Pathol 66: 11-17.
5. DeLotto, Y. and DeLotto, R. (1998) Proteolytic processing of the Drosophila spatzle protein by Easter generates a dimeric NGF-like molecule with ventralising activity. Mech Dev 72: 141-148.
6. Dimopoulos, G., Richman, A., Muller, H.-M. and Kafatos, F.C. (1997) Molecular immune responses of the mosquito Anopheles gambiae to bacteria and malaria parasites. Proc Natl Acad Sci USA 94: 11508-11513.
7. Engstrom, Y. (1998) Insect immune gene regulation. In Molecular Mechanisms of Immune Responses in Insects (Brey, P. and Hultmark, D., eds), pp. 211-244. Chapman & Hall, London.
8. Gorman, M.J., Cornel, A.J., Collins, F.H. and Paskewitz, S.M. (1996) A shared genetic mechanism for melanotic encapsulation of CM-Sephadex beads and a malaria parasite, Plasmodium cynomolgi B, in the mosquito, Anopheles gambiae. Exp Parasitol 84: 380-386.
9. Gwadz, R.W., Kaslow, D., Lee, J.Y., Maloy, W.U., Zasloff, M. and Miller, L.H. (1989) Effects of magainins and cecropins on the sporogonic development of malaria parasites in mosquitoes. Infect Immun 57: 2628-2633.
10. Hagen, H.-E., Klager, S.L., Chan, V., Sakanari, J.A., McKerrow, J.H. and Ham, P.J. (1995) Simulium damnosum s.l. identification of inducible serine proteases following an Onchocerca infection by differential display reverse transcription PCR. Exp Parasitol 81: 249-254.
11. Han, Y.S., Salazar, C.E., Reese-Stardy, S.R., Cornel, A., Gorman, M.J., Collins, F.H. and Paskewitz, S.M. (1997) Cloning and characterization of a serine protease from the human malaria vector, Anopheles gambiae. Insect Molec Biol 6: 385-395.
12. Lee, F.-J.S., Moss, J. and Lin, L.-W. (1992) A simplified procedure for hybridization of RNA blots. Biotechniques 13: 844-846.
13. Lemaitre, B., Nicolas, E., Michaut, L., Riechhart, J.-M. and Hoffmann, J.A. (1996) The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86: 973-983.
14. Liu, C., Hou, R.F., Ashida, M. and Chen, C.C. (1997) Effects of inhibitors of serine protease, phenoloxidase and dopa decarboxylase on the melanization of Dirofilaria immitis microfilariae with Armigeres subalbatus haemolymph in vitro. Parasitology 115: 57-68.
15. Lowenberger, C., Bulet, P., Charlet, M., Hetru, C., Hodgeman, B., Christensen, B.M. and Hoffmann, J.A. (1995) Insect immunity: isolation of three novel inducible antibacterial defensins from the vector mosquito, Aedes aegypti. Insect Biochem Molec Biol 25: 867-573.
16. Lowenberger, C.A., Kamal, S., Chiles, J., Paskewitz, S.M., Bulet, P., Hoffmann, J.A. and Christensen, B.M. (1999) Mosquito-Plasmodium interactions in response to immune activation of the vector. Exp Parasitol 91: 59-69.
17. Luckhart, S., Vodovotz, Y., Cui, L. and Rosenberg, R. (1998) The mosquito Anopheles Stephensi limits malaria parasite development with inducible synthesis of nitric oxide. Proc Natl Acad Sci USA 95: 5700-5705.
18. Muta, T., Hashimoto, R., Toshiyuki, M., Nishimura, H., Yoshihiro, T. and Iwanaga, S. (1990) Proclotting enzyme from horseshoe crab hemocytes. J Biol Chem 265: 22426-22433.
19. Muta, T. and Iwanaga, S. (1996) The role of hemolymph coagulation in innate immunity. Curr Opinion Immunol 8: 41-47.
20. Nakai, K. and Kanehisa, M. (1992) A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics 14: 897-911.
21. Paskewitz, S.M., Brown, M.R., Lea, A.O. and Collins, F.H. (1988) Ultrastructure of the encapsulation of Plasmodium cynomolgi (B strain) on the midgut of a refractory strain of Anopheles gambiae. J Parasitol 74: 432-439.
22. Richman, A.M., Dimopoulos, G., Seeley, D. and Kafatos, F.C. (1997) Plasmodium activates the innate immune response of Anopheles gambiae mosquitoes. EMBO J 16: 6114-6119.
23. Salazar, C.E., Hamm, D., Wesson, D.M., Beard, C.B., Kumar, V. and Collins, F.H.A. (1994) Cytoskeletal actin gene in the mosquito Anopheles gambiae. Insect Mol Biol 3: 1-13.
24. Severson, D.W., Mori, A., Zhang, Y. and Christensen, B.M. (1994) The suitability of restriction fragment length polymorphism markers for evaluating genetic diversity among and synteny between mosquito species. Am J Trop Med Hyg 50: 425-432.
25. Shahabuddin, M., Fields, I., Bulet, P., Hoffmann, J.A. and Miller, L.H. (1998) Plasmodium gallinaceum: differential killing of some mosquito stages of the parasite by insect defensin. Exp Parasitol 89: 103-112.
26. Siden-Kiamos, I., Skavdis, G., Rubio, J., Papagiannakis, G. and Louis, C. (1996) Isolation and characterization of three serine protease genes in the mosquito Anopheles gambiae. Insect Molec Biol 5: 61-71.
27. Von Heijne, G. (1986) A new method for predicting signal sequence cleavage sites. Nucl Acids Res 14: 4683-4690.
28. Zheng, L., Cornel, A.J., Wang, R., Erfle, H., Voss, H., Ansorge, W., Kafatos, F.C. and Collins, F.H. (1997) Quantitative trait loci for refractoriness of Anopheles gambiae to Plasmodium cynomolgi B. Science 276: 425-428.