Marked impairment of protein tyrosine phosphatase 1B activity in adipose tissue of obese subjects with and without type 2 diabetes mellitus

Journal of Laboratory and Clinical Medicine

Volumn 134, Issue 2, 1999, Pages 115-123

  Cheung, Anthony ^b   Kusari, Jyotirmoy ^b   Jansen, David ^b   Bandyopadhyay, Debdutta ^b   Kusari, Anasua ^b   Bryer Ash, Michael ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033180083     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2143(99)90115-4     Document Type: Article

References (62)

1. 1. Kasuga M, Karleson FA, Kahn CR. Insulin stimulates the phosphorylation of the β-subunit of its own receptor. Science 1982;217:185-7.
2. 2. Petruzzelli LM, Ganguly S, Smith CJ, et al. Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-Ll adipocytes and human placenta. Proc Natl Acad Sci USA 1982;79:6792-6.
3. 3. White MF, Maron R, Kahn CR. Insulin rapidly stimulates tyrosine phosphorylation of a Mr 185,000 protein in intact cells. Nature 1985;318:183-6.
4. 4. Rothenberg PL, Lane WS, Karasik A, et al. Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase. J Biol Chem 1991;266:8302-11.
5. 5. Kahn CR. Insulin, diabetogenes and the cause of type 2 diabetes. Diabetes 1994;43:1066-84.
6. 6. White MF, Kahn CR. The insulin signaling system. J Biol Chem 1994;269:1-4.
7. 7. Fischer EH, Charbonneau H, Tonks NK. Protein tyrosine phosphatases - a diverse family of intracellular and transmembrane enzymes. Science 1991;253:401-6.
8. 8. Pot DA, Dixon JE. A thousand and two protein tyrosine phosphatases. Biochim Biophys Acta 1992;1136:35-43.
9. 9. Ramachandran C, Aebersold R, Tonks NK, et al. Sequential dephosphorylation of a multiply phosphorylated insulin receptor peptide by protein tyrosine phosphatases. Biochemistry 1992;31:4232-8.
10. 10. Hashimoto N, Feener EP, Zhang WR, et al. Insulin receptor protein tyrosine phosphatases: leucocyte common antigen-related phosphatase rapidly deactivates the insulin receptor kinase by preferential dephosphorylation of the receptor regulatory domain. J Biol Chem 1992;267:811-3.
11. 11. Ahmad F, Considine RV, Goldstein BJ. Increased abundance of the receptor-type protein-tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects. J Clin Invest 1995;95:2806-12.
12. 12. Tappia PS, Sharma RP, Sale GJ. Dephosphorylation of autophosphorylated insulin and epidermal growth factor receptors by two major subtypes of protein-tyrosine-phosphatase from human placenta. Biochem J 1991;278:69-74.
13. 13. Tonks NK. Protein tyrosine phosphatases and the control of cellular signaling responses. In: Hidaka H, Nairn AC, editors. Intracellular signal transduction, advances in pharmacology (vol 36). San Diego: Academic Press; 1996. p. 91-119.
14. 14. Goldstein BJ. Regulation of insulin receptor signaling by protein tyrosine dephosphorylation. Receptor 1993;3:1-15.
15. 15. Kusari J, Kenner KA, Suh KI, et al. Skeletal muscle protein tyrosine phosphatase activity and tyrosine phosphatase IB content are associated with insulin action and resistance. J Clin Invest 1994;93:1156-62.
16. 16. Grupposo PA, Boylan JM, Smiley BL. Hepatic protein tyrosine phosphatases in the rat. Biochem J 1991;274:361-7.
17. 17. Charbonneau H, Tonks NK, Kumar S, et al. Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins. Proc Natl Acad Sci USA 1989;86:5252-6.
18. 18. McGuire MC, Fields RM, Nyomba BL, et al. Abnormal regulation of protein tyrosine phosphatase activities in skeletal muscle of insulin-resistant humans. Diabetes 1991;40:939-42.
19. 19. Worm D, Vinten J, Stachr P, Henriksen JE, Handberg A, Beck-Nielsen H. Altered basal and insulin-stimulated phosphotyrosine phosphatase (PTPase) activity in skeletal muscle from NIDDM patients compared with control subjects. Diabetologia 1996;39:1208-14.
20. 20. Ahmad F, Azevedo JL, Cortright R, Dohm GL, Goldstein BJ. Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes. Ann Intern Med 1997;100:449-58.
21. 21. Worm D, Handberg A, Hoppe E, et al. Decreased skeletal muscle phosphotyrosine phosphatase (PTPase) activity towards insulin receptors in insulin-resistant Zucker rats measured by delayed europium fluorescence. Diabetologia 1996;39:142-8.
22. 22. Olichon-Berthe C, Haugel de Mouzon S, Peraldi P, et al. Insulin receptor dephosphorylation by phosphotyrosine phosphatases obtained from insulin-resistant obese mice. Diabetologia 1994;37:56-60.
23. 23. Ahmad F, Goldstein BJ. Increased abundance of specific skeletal muscle protein tyrosine phosphatases in a genetic model of obesity and insulin resistance. Metabolism 1995;44:1175-84.
24. 24. Meyerovitch J, Rothenberg P, Schlechter Y, et al. Vanadate normalizes hyperglycemia in two mouse models of non-insulin-dependent diabetes mellitus. J Clin Invest 1991;87:1286-94.
25. 25. Maegawa H, Ide R, Hasegawa M, et al. Thiazolidine derivatives ameliorate high glucose-induced insulin resistance via the normalization of protein-tyrosine phosphatase activities. J Biol Chem 1995;270:7724-30.
26. 26. Goldstein BJ. Protein tyrosine phosphatases and the regulation of insulin action. J Cell Biochem 1992;48:33-42.
27. 27. Ahmad F, Li PM, Meyerovitch J, et al. Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase IB in negative regulation of the insulin action pathway. J Biol Chem 1995;270:20503-8.
28. 28. Polonsky KS, Given BD, Van Cauter E. Twenty-four hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. J Clin Invest 1988;81:441-8.
29. 29. Harris MI, Hadden WC, Knowler, et al. The prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in US population aged 20-74. Diabetes 1987;36:523-34.
30. 30. Harris MI, Hadden WC, Knowler WC, et al. International criteria for the diagnosis of diabetes and impaired glucose tolerance. Diabetes Care 1985;8:562-7.
31. 31. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-549.
32. 32. Brown-Shimer S, Johnson KA, Hill DE, et al. Effect of protein tyrosine phosphatase IB expression on transformation by the human neu oncogene. Cancer Res 1992;52:478-82.
33. 33. Ullrich A, Bell JR, Chen EY, et al. Human insulin receptor and its relationship to tyrosine kinase family of oncogenes. Nature 1985;313:756-61.
34. 34. Kenner KA, Hill DE, Olefsky JM, et al. Regulation of protein tyrosine phosphatases by insulin and insulin-like growth factor I. J Biol Chem 1993;268:25455-62.
35. 35. Shacter E. Organic extraction of phosphate with isobutanol/toluene. Anal Biochem 1984;138:416-20.
36. 36. Kasuga M, White MF, Kahn CR. Phosphorylation of the insulin receptor in cultured hepatoma cells in a solubilized system. Methods Enzymol 1985; 109:609-21.
37. 37. Caro JF, Sinha MK, Raju SM, et al. Insulin receptor kinase in human skeletal muscle from subjects with and without non-insulin-dependent diabetes. J Clin Invest 1987;79:1330-7.
38. 38. Thies RS, Molina JM, Ciaraldi TP, et al. Insulin receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese and NIDDM subjects. Diabetes 1990;39:250-9.
39. 31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate: evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus. J Clin Invest 1992;89:1069-75.
40. 13C nuclear magnetic resonance spectroscopy. N Engl J Med 1990;322:223-8.
41. 41. Garvey WT, Maianu L, Hancock JA, et al. Gene expression of GLUT4 in skeletal muscle from insulin-resistant patients with obesity, IGT, GDM and NIDDM. Diabetes 1992;41:465-75.
42. 42. Kahn BB. Alterations in glucose transporter expression and function in diabetes: mechanisms for insulin resistance. J Cell Biochem 1992;48:122-8.
43. 43. Benecke H, Flier JS, Moller DE. Alternatively spliced variant of the insulin receptor protein. Expression in normal and diabetic human tissue. J Clin Invest 1992;89:2066-70.
44. 44. Zander NF, Lorenzen JA, Cool DE, et al. Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system. Biochemistry 1991;30:6964-70.
45. 45. Cicirelli MF, Tonks NK, Diltz CD, et al. Microinjection of a protein-tyrosine phosphatase inhibits insulin action in Xenopus oocytcs. Proc Natl Acad Sci USA 1990;87:5514-8.
46. 46. Kenner KA, Anyanwu E, Olefsky JM, et al. PTPase IB is a negative regulator of insulin and IGF-I stimulated signalling. J Biol Chem 1996;271:19810-6.
47. 47. Ide R, Maegawa H, Kikkawa R, et al. High glucose condition activates protein tyrosine phosphatases and deactivates insulin receptor function in insulin-sensitive rat-1 fibroblasts. Biochem Biophys Res Commun 1994;201:71-7.
48. 48. Ren J-M, Li P-M, Zhang W-R, Sweet L-J, Cline G, Shulman GI, et al. Transgenic mice deficient in the LAR protein-tyrosine phosphatse exhibit profound defects in glucose homeostasis. Diabetes 1998;47:493-7.
49. 49. Blackard WG, Clore JN, Glickman PS, et al. Insulin sensitivity of splanchnic and peripheral adipose tissue in vivo in morbidly obese man. Metabolism 1993;42:1195-200.
50. 50. Edens NK, Fried SK, Kral JG, et al. In vitro lipid synthesis in human adipose tissue from three abdominal sites. Am J Physiol 1993;265:E374-9.
51. 51. Herrera R, Rosen OM. Autophosphorylation of the insulin receptor in vitro: designation of phosphorylation sites and correlation with receptor kinase activation. J Biol Chem 1986;261:11980-5.
52. 52. Matthews RJ, Cahir ED, Thomas ML. Identification of an additional member of the protein-tyrosine-phosphatase family: evidence for alternate splicing in the tyrosine phosphatase domain. Proc Natl Acad Sci USA 1990;87:4444-8.
53. 53. Keese D, Sell SM. Alternatively spliced variants of PTP-1B: ratio in human monocytes. Diabetes 1996;45(suppl 2):106A.
54. 54. Cummings DE, Brandon EP, Planas JV, et al. Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A. Nature 1996;382:622-6.
55. 55. Nishida K, Ohara T, Johnson J, et al. Na+/K+-ATPase activity and its alpha II subunit gene expression in rat skeletal muscle: influence of diabetes, fasting and refeeding. Metabolism 1992;41:56-63.
56. 56. Spiegelman BM, Flier JS. Adipogenesis and obesity: rounding out the big picture. Cell 1996;87:377-89.
57. - ential regulation of insulin signaling by TNF-α. Endocrinology 1998;139:4928-35.
58. 58. Knutson VP. Cellular trafficking and processing of the insulin receptor. FASEB J 1991;5:2130-8.
59. 59. Carpentier JL. Insulin receptor internalization: molecular mechanisms and physiopathological implications. Diabetologia 1994;37(suppl 12):S117-24.
60. 60. Backer JM, Kahn CR, White MF. Tyrosine phosphorylation of the insulin receptor during insulin-stimulated internalization in rat hepatoma cells. J Biol Chem 1989;264:1694-701.
61. 61. Bandyopadhyay D, Kusari A, Kenner KA, et al. Protein-tyrosinc phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin. J Biol Chem 1997;272:1639-45.
62. 62. Yamauchi K, Milarski KL, Saltiel AR, et al. Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling. Proc Natl Acad Sci USA 1995;92:664-8.