Stimulation of 5-HT(1A) receptors by systemic or medial septum injection induces anxiogenic-like effects and facilities acquisition of a spatial discrimination task in mice

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 23, Issue 6, 1999, Pages 1113-1133

  Micheau, Jacques ^a   Van Marrewijk, Barbara ^a  

^a CNRS   (France)

Author keywords

5 HT(1A) receptor; 8 OH DPAT; Anxiety; Mice; Spatial learning

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; SEROTONIN 1A RECEPTOR; SEROTONIN 1 RECEPTOR; SEROTONIN AGONIST; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; CONTROLLED STUDY; DISCRIMINATION LEARNING; DISEASE MODEL; MALE; MAZE TEST; MEMORY; MOUSE; NONHUMAN; SPATIAL DISCRIMINATION; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; INJECTION; MOTOR ACTIVITY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; SEPTUM PELLUCIDUM;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; ANXIETY; DISCRIMINATION LEARNING; INJECTIONS; MALE; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEPTUM OF BRAIN; SEROTONIN AGONISTS;

EID: 0033169209     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(99)00057-3     Document Type: Article

References (54)

1. Alreja, M. (1996) Excitatory actions of serotonin on GABAergic neurones of the medial septum and diagonal band of Broca. Synapse, 22: 15-27.
2. 1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively. Eur. J. Pharmacol., 264: 259-264.
3. 1A agonist, 8-OH-DPAT on instrumental performance in rats. Psychopharmacology, 125: 79-88.
4. Béracochéa, D., Krazem, A. and Jaffard R. (1995) Methyl beta-carboline-3-carboxylate reverses the working memory deficits induced either by chronic alcohol consumption or mammillary body lesions in BALB/c mice. Psychobiology, 23: 52-58.
5. 1A syndrome. Pharmacol. Biochem. Behav., 57: 897-908.
6. Bonvento, G., Scatton, B., Claustre, Y. and Rouquier L. (1992) Effect of local injection of 8-OH-DPAT into the dorsal or median raphe nuclei on extracellular levels of serotonin in serotonergic projection areas in the rat brain. Neurosci. Lett, 137: 101-104.
7. Buhot, M.C. (1997) Serotonin receptors in cognitive behaviors. Cur. Op. Neurobiol., 7: 243-254.
8. 1B receptors in the rat. Hippocampus, 5: 198-208.
9. 1A receptors in the hippocampus. Behav. Brain Res., 67: 67-74.
10. 1A receptors. Br J. Pharmacol., 105: 720-726.
11. 1A receptors causes amnesia and anxiolytic-like but not antidepressant-like effects in the rat. Eur. J. Pharmacol., 234: 215-221.
12. 1A receptor agonist, impairs performance in a passive avoidance task. Eur. J. Pharmacol., 211: 227-234.
13. Cassel, J.-C. and Jeltsch H. (1995) Serotonergic modulation of cholinergic function in the central nervous system: Cognitive implications. Neuroscience, 69: 1-41.
14. 1A receptor agonists improve the performance of normal and scopolamine-impaired rats in an opérant delayed matching to position task. Psychopharmacology, 116: 135-142.
15. Damasio, A.R. (1994) Descartes' Error: Emotion, Reason, and the Human Brain, A. Grosset/Putman Books.
16. Deakin, J.F.W., Graeff F.G. and Guimaraes F.S. (1992) 5HT receptor subtypes and the modulation of aversion, In Central Serotonin Receptors and Psychotropic Drugs, C.A. Marsden and D.J. Heal (Eds.), pp. 147-174. Blackwell Scientific Publications, Oxford.
17. Decker, M.W. and McGaugh J.L. (1991) The role of interactions between the cholinergic system and other neuromodulatory systems in learning and memory. Synapse, 7: 151-168.
18. 2 agonists. Br. J. Pharmacol., 89: 377-384.
19. File, S. (1993) The interplay of learning and anxiety in the elevated plus maze. Behav. Brain Res., 58: 199-202.
20. 1A receptor modulation of anxiety in two ethological animal tests. J. Neurosci., 16: 4810-4815.
21. Givens, B. and Olton D.S. (1990) Cholinergic and gabaergic modulation of medial septal area: Effect on working memory. Behav. Neurosci., 104: 849-855.
22. Givens, B. and Olton D.S. (1994) Local modulation of basal forebrain: Effects on working and reference memory. J. Neurosci., 14: 3578-3587.
23. Gower, A.J. (1992) 5-HT receptors and cognitive function. In Central Serotonin Receptors and Psychotropic Drugs, C.A. Marsden and D.J. Heal (Eds.), pp. 239-259. Blackwell Scientific Publications, Oxford.
24. Gray, J.A. (1982) The Neuropsychology of Anxiety: An Enquiry into the Functions of the Septo-Hippocampal System. Oxford University Press, Oxford.
25. Guillou, J.-L., Micheau, J. and R. Jaffard (1993) Effects of intrahippocampal injections of somatostatin and cysteamine on spatial discrimination learning in mice. Psychobiology, 21: 265-271.
26. Handley, S.L. and McBlane J.W. (1991) 5-HT: The disengaging transmitter? J. Psychopharmacol., 5: 322-326.
27. Handley, S.L., McBlane, J.W., Critchley, M.A.E. and Njung'e K. (1993) Multiple serotonin mechanisms in animal models of anxiety: Environmental, emotional and cognitive factors. Behav. Brain Res., 58: 203-210.
28. Jaffard, R. and Micheau J. (1994) Central cholinergic system; learning and memory. In The Memory System of the Brain. Advanced Series in Neuroscience, Vol. 4, J. Delacour (Ed.), pp 389-430, World Scientific, Singapore.
29. 1A receptors agonists and in their inhibitory effects on the firing of serotonergic neurons in the rat? J. Pharmacol. Exp. Ther., 272: 920-929.
30. Kelsey, J.E. and Landry B.A. (1988) Medial septal lesions disrupt spatial mapping ability in rats. Behav. Neurosci., 102: 289-293.
31. 1A receptors are expressed by a subpopulation of cholinergic neurons in the rat medial septum and diagonal band of Broca - A double immunocytochemical study. Neuroscience, 74: 143-154.
32. Kinney, G.G., Kocsis, B. and Vertes R.P. (1996) Medial septal unit firing characteristics following injections of 8-OH-DPAT into the median raphe nucleus. Brain Res., 708: 116-122.
33. 1A autoreceptors of the dorsal or median raphe nuclei. J. Pharmacol. Exp. Ther., 269: 1268-1278.
34. Landfield, P.W., McGaugh, J.L. and Tusa R.J. (1971) Theta rhythm: A temporal correlate of memory storage processes in the rat. Science, 175: 87-89.
35. Marighetto, A., Micheau, J. and Jaffard R. (1993) Relationships between testing-induced alterations of hippocampal cholinergic activity and memory performance on two spatial tasks in mice. Behav. Brain Res., 56: 133-144.
36. Markowska, A., Olton, D.S. and Givens B. (1995) Cholinergic manipulations in the medial septal area: Aged-realated effects on working memory and hippocampal electrophysiology. J. Neurosci., 15: 2063-2073.
37. McBlane, J.W., Critchley, M.A.E. and Handley S.L. (1992) Light intensity influences the response to 8-OH-DPAT in the elevated X-maze. Br. J. Pharmacol., 105: 221p.
38. Milner, T.A. and Veznedaroglu E. (1993) Serotonin-containing terminals synapse on septohippocampal neurons in the rat. J. Neurosci. Res., 36: 260-271.
39. 1A receptors in rat cortex, hippocampus and cholinergic basal forebrain nuclei during aging. J. Chem. Neuroanat, 13: 53-61.
40. 1A receptor agonist, in the rat. Eur. J. Pharmacol., 234: 29-34.
41. Olton, D.S., Becker, J.T. and Handelman G.E. (1979) Hippocampus space and memory. Behav. Brain Sci., 2: 313-365.
42. Pellow, S., Chopin, P., File, S.E. and Briley M. (1985) Validation of open: Closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci. Meth., 14: 149-167.
43. 1A receptor in the rat brain: Correlation with receptor binding. J. Neurosci., 12: 440-453.
44. Saito, H., Matsumoto, M., Togashi, H. and Yoshioka M. (1996) Functional interaction between serotonin and other neuronal systems: Focus on in vivo microdialysis studies. Japan. J. Pharmacol., 70: 203-225.
45. Santucci, A.C., Knott, P.J. and Haroutunian V. (1996) Excessive serotonin release, not depletion, leads to memory impairments in rats. Eur. J. Pharmacol., 295: 7-17.
46. Sharp, T., Bramwell, R.S., Hjorth, S. and Grahame-Smith G.D. (1989) Phamacological characterization of 8-OH-DPAT-induced inhibition of rat hippocampal 5-HT release in vivo as measured by microdialysis. Br. J. Pharmacol., 98: 989-997.
47. 1B agonists: A comparative study with dorsal raphe neurons. Neuropharmacology, 27: 707.
48. Steckler, T. and Sahgal A. (1995) The role of serotonergic-cholinergic interactions in the mediation of cognitive behaviour. Behav. Brain Res., 67: 165-199.
49. 1A receptor agonists. Neuropharmacology, 32: 977-985.
50. Treit, D., Robinson, A., Rotzinger, S. and Pesold C. (1993) Anxiolytic effects of serotonergic interventions in the shock-probe burying test and the elevated plus-maze test. Behav. Brain Res., 54: 23-34.
51. 1A agonists, 8-OH-DPAT and buspirone, produces hippocampal theta rhythm in the rat. Neuroscience, 60: 441-451.
52. 1A receptor agonist 8-OH-DPAT on spatial short-term working memory in rats. Behav. Brain Res., 84: 247-258.
53. Winson, J. (1978) Loss of hippocampal theta rhythm resulyts in spatial memory deficit in the rat. Science, 210: 160-163.
54. 1A receptors in memory. Pharmacol. Biochem. Behav., 27: 625-628.