The specificity of a weak γδ TCR interaction can be modulated by the glycosylation of the ligand

Journal of Immunology

Volumn 163, Issue 1, 1999, Pages 288-294

  Hampl, Johannes ^a,b   Schild, Hansjörg ^a   Litzenberger, Christa ^a,c   Baron, Miriam ^a,d   Crowley, Michael P ^a   Chien, Yueh Hsiu ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SRI INTERNATIONAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN; PROTEIN SUBUNIT; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; MOLECULAR DYNAMICS; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; REGULATORY MECHANISM;

ANIMALS; ANTIGEN PRESENTATION; CHO CELLS; CLONE CELLS; CRICETINAE; CYTOCHROME C GROUP; EPITOPES, T-LYMPHOCYTE; GLYCOSYLATION; HISTOCOMPATIBILITY ANTIGENS CLASS II; LIGANDS; MICE; MOTHS; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES; TRANSFECTION;

EID: 0033169044     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Haas, W., P. Pereira, and S. Tonegawa. 1993. Gamma/delta cells. Annu. Rev. Immunol. 11:637.
2. Havran, W. L., and R. Boismenu. 1994. Activation and function of γδ T cells. Curr. Opin. Immunol. 6:442.
3. Kaufmann, S. H. 1994. Bacterial and protozoal infections in genetically disrupted mice. Curr. Opin. Immunol. 6:518.
4. Ohga, S., Y. Yoshikai, Y. Takeda, K. Hiromatsu, and K. Nomoto. 1990. Sequential appearance of γδ- and αΒ-bearing T cells in the peritoneal cavity during an i.p. infection with Listeria monocytogenes. Eur. J. Immunol. 20:533.
5. Ferrick, D. A., M. D. Schrenzel, T. Mulvania, B. Hsieh, W. G. Ferlin, and H. Lepper. 1995. Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo. Nature 373:255.
6. Hiromatsu, K., Y. Yoshikai, G. Matsuzaki, S. Ohga, K. Muramori, K. Matsumoto, J. A. Bluestone, and K. Nomoto. 1992. A protective role of γδ T cells in primary infection with Listeria monocytogenes in mice. J. Exp. Med. 175:49.
7. Carding, S. R., W. Allan, S. Kyes, A. Hayday, K. Bottomly, and P. C. Doherty. 1990. Late dominance of the inflammatory process in murine influenza by γδ+ T cells. J. Exp. Med. 172:1225.
8. Hara, T., Y. Mizuno, K. Takaki, H. Takada, H. Akeda, T. Aoki, M. Nagata, K. Ueda, G. Matsuzaki, Y. Yoshikai, et al. 1992. Predominant activation and expansion of Vγ9-bearing γδ T cells in vivo as well as in vitro in Salmonella infection. J. Clin. Invest. 90:204.
9. Hou, S., J. M. Katz, P. C. Doherty, and S. R. Carding. 1992. Extent of γδ T cell involvement in the pneumonia caused by Sendai virus. Cell. Immunol. 143:183.
10. Bukowski, J. F., C. T. Morita, and M. B. Brenner. 1994. Recognition and destruction of virus-infected cells by human γδ CTL. J. Immunol. 153:5133.
11. Mukasa, A., M. Lahn, E. K. Pflum, W. Born, and R. L. O'Brien. 1997. Evidence that the same γδ T cells respond during infection-induced and autoimmune inflammation. J. Immunol. 159:5787.
12. Matis, L. A., A. M. Fry, R. Q. Cron, M. M. Cotterman, R. F. Dick, and J. A. Bluestone. 1989. Structure and specificity of a class II MHC alloreactive γδ T cell receptor heterodimer. Science 245:746.
13. - T lymphocytes. J. Exp. Med. 168:1899.
14. Schild, H., N. Mavaddat, C. Litzenberger, E. W. Ehrich, M. M. Davis, J. A. Bluestone, L. Matis, R. K. Draper, and Y. H. Chien. 1994. The nature of major histocompatibility complex recognition by γδ T cells. Cell 76:29.
15. Weintraub, B. C., M. R. Jackson, and S. M. Hedrick. 1994. γδ T cells can recognize nonclassical MHC in the absence of conventional antigenic peptides. J. Immunol. 153:3051.
16. Bonneville, M., K. Ito, E. G. Krecko, S. Itohara, D. Kappes, I. Ishida, O. Kanagawa, C. A. Janeway, D. B. Murphy, and S. Tonegawa. 1989. Recognition of a self major histocompatibility complex TL region product by γδ T-cell receptors. Proc. Natl. Acad. Sci. USA 86:5928.
17. Groh, V., A. Steinle, S. Bauer, and T. Spies. 1998. Recognition of stress-induced MHC molecules by intestinal epithelial γδ T cells. Science 279:1737.
18. Crowley, M. P., Z. Reich, N. Mavaddat, J. D. Altman, and Y. H. Chien. 1997. The recognition of the nonclassical MHC class I molecule, T10, by the γδ T cell, G8. J. Exp. Med. 185:1223.
19. Honig, B., and A. Nicholls. 1995. Classical electrostatics in biology and chemistry. Science 268:1144.
20. Ehrich, E. W., B. Devaux, E. P. Rock, J. L. Jorgensen, M. M. Davis, and Y. H. Chien. 1993. T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen. J. Exp. Med. 178:713.
21. Ozato, K., N. Mayer, and D. H. Sachs. 1980. Hybridoma cell lines secreting monoclonal Abs to mouse H-2 and Ia antigens. J. Immunol. 124:533.
22. Schrader, J. W., L. I. Clark, R. M. Crapper, and G. H. Wong. 1983. T-cell stimulating factor and interferon-γ: T-cell lymphokines with multiple targets. Lymphokine Res. 2:83.
23. Fiering, S., J. P. Northrop, G. P. Nolan, P. S. Mattila, G. R. Crabtree, and L. A. Herzenberg. 1990. Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor. Genes Dev. 4:1823.
24. Roederer, M., S. Fiering, and L. A. Herzenberg. 1991. FACS-Gal: flow cytometric analysis and sorting of cells expressing reporter gene constructs. Methods Companion Methods Enzymol. 2:248.
25. Altman, J. D., P. A. Reay, and M. M. Davis. 1993. Formation of functional peptide complexes of class II major histocompatibility complex proteins from subunits produced in Escherichia coli. Proc. Natl. Acad. Sci. USA 90:10330.
26. Altman, J. D., P. A. H. Moss, P. J. R. Goulder, D. H. Barouch, M. G. McHeyzer-Williams, J. I. Bell, A. J. McMichael, and M. M. Davis. 1996. Phenotypic analysis of antigen-specific T lymphocytes. Science 274:94.
27. Gutgemann, I., A. M. Fahrer, J. D. Altman, M. M. Davis, and Y.-h. Chien. 1998. Induction of rapid T cell activation and tolerance by systemic presentation of an orally administered antigen. Immunity 8:667.
28. Boniface, J. J., J. D. Rabinowitz, C. Wuelfing, J. Hampl, Z. Reich, J. D. Altman, R. M. Kantor, C. Beeson, H. M. McConnell, and M. M. Davis. 1998. Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands. Immunity 9:459.
29. Crawford, F., H. Kozono, J. White, P. Marrack, and J. Kappler. 1998. Detection of antigen-specific T cells with multivalent soluble Class II MHC covalent peptide complexes. Immunity 8:675.
30. Hampl, J., Y.-h. Chien, and M. M. Davis. 1997. CD4 augments the response of a T cell to agonist but not antagonist ligands. Immunity 7:379.
31. Wettstein, D. A., J. J. Boniface, P. A. Reay, H. Schild, and M. M. Davis. 1991. Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH. J. Exp. Med. 174:219.
32. Presley, J. F., R. K. Draper, and D. T. Brown. 1991. Defective transport of Sindbis virus glycoproteins in End4 mutant Chinese hamster ovary cells. J. Virol. 65:1332.
33. Kavathas, P., F. H. Bach, and R. De Mars. 1980. Gamma ray-induced loss of expression of HLA and glyoxalase I alleles in lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 77:4251.
34. Swiedler, S. J., J. H. Freed, A. L. Tarentino, T. H. Plummer, Jr., and G. W. Hart. 1985. Oligosaccharide microheterogeneity of the murine major histocompatibility antigens: reproducible site-specific patterns of sialylation and branching in asparagine-linked oligosaccharides. J. Biol. Chem. 260:4046.
35. Davies, D. R., E. A. Padlan, and S. Sheriff. 1990. Ab-Antigen complexes. Annu. Rev. Bochem. 59:439.
36. Garcia, K., M. Degano, R. Stanfield, A. Brunmark, M. Jackson, P. Peterson, L. Teyton, and I. Wilson. 1996. An αΒ T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science 274:209.
37. Garboczi, D. N., P. Gosh, U. Utz, Q. R. Fan, W. E. Biddison, and D. C. Wiley. 1996. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 384:134.
38. Stern, L. J., J. H. Brown, T. S. Jardetzky, J. C. Gorga, R. G. Urban, J. L. Strominger, and D. C. Wiley. 1994. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 368: 215.
39. Clackson, T., and J. A. Wells. 1995. A hot spot of binding energy in a hormone-receptor interface. Science 267:383.
40. Villanueva, M. S., C. J. Beckers, and E. G. Pamer. 1994. Infection with Listeria monocytogenes impairs sialic acid addition to host cell glycoproteins. J. Exp. Med. 180:2137.
41. Boon, T., P. G. Coulie, and B. Van den Eynde. 1997. Tumor antigens recognized by T cells. Immunol. Today 18:267.