A complementary peptide vaccine that induces T cell anergy and prevents experimental allergic neuritis in Lewis rats

Journal of Immunology

Volumn 163, Issue 1, 1999, Pages 476-482

  Araga, Shigeru ^a   Kishimoto, Masahiro ^a   Doi, Satoko ^a   Nakashima, Kenji ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; MYELIN PROTEIN; POLYCLONAL ANTIBODY; T LYMPHOCYTE RECEPTOR;

ACTIVE IMMUNIZATION; ALLERGIC NEUROPATHY; ANIMAL EXPERIMENT; ARTICLE; CLONAL ANERGY; FEMALE; GROWTH REGULATION; IMMUNOGENICITY; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE ACTIVATION; VACCINE PRODUCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; CATTLE; CELL LINE; CLONAL ANERGY; EPITOPES, T-LYMPHOCYTE; FEMALE; IMMUNE SERA; INJECTIONS, SUBCUTANEOUS; MYELIN P2 PROTEIN; NEURITIS, AUTOIMMUNE, EXPERIMENTAL; PEPTIDE FRAGMENTS; RABBITS; RATS; RATS, INBRED LEW; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES; VACCINES, SYNTHETIC;

EID: 0033168961     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Araga, S., R. D. LeBoeuf, and J. E. Blalock. 1993. Prevention of experimental autoimmune myasthenia gravis by manipulation of the immune network with a complementary peptide for the acetylcholine receptor. Proc. Nalt. Acad. Sci. USA 90:8747.
2. Araga, S., and J. E. Blalock. 1994. Use of complementary peptides and their Abs in B cell-mediated autoimmune disease: prevention of experimental autoimmune myasthenia gravis with a peptide vaccine. ImmunoMethods 5:130.
3. Bost, K. L., E. M. Smith, and J. E. Blalock. 1985. Similarity between the corticotropin (ACTH) receptor and a peptide by an RNA that is complementary to ACTH mRNA. Proc. Natl. Acad. Sci. USA 82:1372.
4. Blalock, J. E. 1990. Complementarity of peptides specified by sense and antisense strands of DNA. Trends Biotechnol. 8:140.
5. Clarke, B. L., and J. E. Blalock. 1991. Characteristics of peptides specified by antisense nucleic acids. In Antisense Nucleic Acids and Proteins: Fundamental and Applications. J. N. M. Mol and A. R. van der Krol, eds. Marcel Dekker Inc., New York, p. 169.
6. Smith, L. R., K. L. Bost, and J. E. Blalock. 1987. Generation of idiotypic and anti-idiotypic Abs by immunization with peptides encoded by complementary RNA: a possible molecular basis for the network theory. J. Immunol. 138:7.
7. Whitaker, J. N., B. E. Sparks, D. P. Walker, R. Goodin, and E. N. Benveniste. 1989. Monoclonal idiotypic and anti-idiotypic Abs produced by immunization with peptides specified by a region of human myelin basic protein mRNA and its complement. J. Neuroimmunol. 22:157.
8. Brostoff, S., P. Burnett, P. Lampert, and E. Eylar. 1972. Isolation and characterization of a protein from sciatic nerve myelin responsible for experimental allergic neuritis. Nat. New. Biol. 235:210.
9. Brosnan, J., R. Craggs, R. King, and P. Thomas. 1984. Attempts to transfer experimental allergic neuritis with lymphocytes. J. Neuroimmunol. 6:373.
10. Linington, C., S. Izumo, M. Suzuki, K. Uyemura, R. Meyermann, and H. Wekerle, 1984. A permanent rat T cell line that mediates experimental allergic neuritis in the Lewis rat in vivo. J. Immunol. 133:1946.
11. Rostami, A., J. Burns, M. Brown. J. Rosen, B. Zweiman, R. Lisak, and D. Pleasure. 1985. Transfer of experimental allergic neuritis with P2-reactive T cell lines. Cell. Immunol. 91:354.
12. Bai, X., J. Zhu, G. Zhang, G. Kaponides, B. Hojeberg, P. van der Meide, and H. Link. 1997. IL-10 suppresses experimental autoimmune neuritis and down-regulates TH1-type immune responses. Clin. Immunol. Immunopathol. 83:117.
13. Rostami, A., S. Gregorian, M. Brown, and D. Pleasure. 1990. Induction of severe experimental autoimmune neuritis with a synthetic peptide corresponding to the 53-78 amino acid sequence of the myelin P2 protein. J. Neuroimmunol. 30:145.
14. Rostami, A., and S. Gregorian. 1991. Peptide 53-78 of myelin P2 protein is a T cell epitope for the induction of experimental autoimmune neuritis. Cell. Immunol. 132:433.
15. Olee, T., H. Powell, and S. Brostoff. 1990. New minimum length requirement for a T cell epiotope for experimental allergic neuritis. J. Neuroimmunol. 27:187.
16. Power, H., T. Olee, S. Brostoff, and A. Mizisin. 1991. Comparative histology of experimental allergic neuritis induced with minimum length neuritogenic peptides by adoptive transfer with sensitized cells or direct sensitizalion. J. Neuropathol. Exp. Neurol. 50:658.
17. Cammer, W. 1979. Carbonic anhydrase activity in myelin from sciatic nerves of adult and young rats: quantitation and inhibitor sensitivity. J. Neurochem. 32:651.
18. Ishque, A., T. Hofmann, and E. Eylar. 1982. The complete amino acid sequence of the rabbit P2 protein. J. Biol. Chem. 257:592.
19. Harlow, E., and D. Lane. 1988. Monoclonal Abs. In Antibodies Laboratory Manual. Cold Spring Harbor Laboratory, New York, p. 84.
20. Adachi, A., S. Araga, and K. Takahashi. 1992. Immunosuppressive effect of FK506 on experimental allergic neuritis in Lewis rats: changes of T cell subsets, Intern. Med. 31:6.
21. Araga, S., and J. E. Blalock. 1994. Prevention of experimental autoimmune myasthenia gravis (EAMG) by immunization with complementary peptides to T-and B-cell epitopes. FASEB J. 8:A745.
22. Ashwell, J. D., R. E. Cunningham, P. Noguchi, and D. Hernandez. 1987. Cell growth cycle block of T cell hybridomas upon activation with antigen. J. Exp. Med. 165:173.
23. Smith, L. R., D. H. Kono, D. Asthana, R. S. Balderas, Y. Fujii, J. Lindstrom, and A. N. Theofilopoulos, 1994. T cell receptor Vβ15 dominates the antiacetylcholine receptor response in Lewis rat T cell lines. J. Immunol. 152:2596.
24. Kinebuchi, M., A. Matsuura, T. Ogiu, and K. Kikuchi. 1997. Derived overexpression of TCRβ, TCRγ, CD4 and CD8 on thymic lymphomas induced by 1-propyl-1-nitrosourea. J. Immunol. 159:748.
25. Schwartz, R. 1990. A cell culture model for T lymphocyte clonal anergy. Science 248:349.
26. Schwartz, R. 1996. Models of T cell anergy: is there a common molecular mechansm? J. Exp. Med. 184:1.
27. Schwartz, R. 1997. T cell clonal anergy. Curr. Opin. Immunol. 9:351.
28. Harding, F., J. McArthur, J. Gross, D. Raulet, and J. Allison. 1992. CD28-mediated signalling co-stimulates murine T cells and prevent induction of anergy in T-cell clones. Nature 356:607.
29. Jenkins, M., and R. Schwartz. 1987. Antigen presentation by chemically modified splenocytes induces antigen-specific T-cell unresponsiveness in vitro and in vivo. J. Exp. Med. 165:302.
30. Salojin, K., J. Zhang, J. Madrenas, and T. Delovitch. 1998. T-cell anergy and altered T-cell receptor signaling: effects on autoimmune disease. Immunol. Today 19:468.
31. Zhou, S. R., and J. N. Whitaker. 1993. Specific modulation of T cells and murine experimental allergic encephalomyelitis by monoclonal anti-idiotypic Abs. J. immunol. 150:1629.
32. Zhou, S. R., and J. N. Whitaker. 1994. Use of complementary peptides and their Abs in T-cell-mediated autoimmune disease: experiments with myelin basic protein. ImmunoMethods 5:136.
33. Zhou, S. R., and J. N. Whitaker. 1996. Active immunization with complementary peptide PBM 9-1: preliminary evidence that it modulates experimental allergic encephalomyelitis in PL/J mice and Lewis rats. J. Neurosci. Res. 45:439.
34. Vandenbark, A., G. Hashim, and H. Offner. 1989. Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis. Nature 341:541.
35. Howell, M., S. Winters, T. Olee, H. C. Powell, D. Carlo, and S. Brostoff. 1989. Vaccination against experimental allergic encephalomyelitis with T cell receptor peptides. Science 246:668.
36. - regulatory T cells and T cell clones presenting TCR peptide: its implication for TCR vaccination against experimental autoimmune encephalomyelitis. J. Immunol. 157:-1781.artno;008928