Genomic structure and functional characterization of NBPhox (PMX2B), a homeodomain protein specific to catecholaminergic cells that is involved in second messenger-mediated transcriptional activation

Genomics

Volumn 59, Issue 1, 1999, Pages 40-50

  Yokoyama, Masahiro ^a   Watanabe, Hirotaka ^a   Nakamura, Motonao ^a  

^a JAPAN TOBACCO INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN;

ARTICLE; CATECHOLAMINE NERVE CELL; CHROMOSOMAL LOCALIZATION; GENE SEQUENCE; GENE STRUCTURE; GENETIC CONSERVATION; GENETIC TRANSCRIPTION; HUMAN; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN ANALYSIS; REGULATORY MECHANISM; SECOND MESSENGER; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

VERTEBRATA;

EID: 0033166906     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1999.5845     Document Type: Article

References (41)

1. Acampora D., Mazan S., Avantaggiato V., Barone P., Tuorto F., Lallemand Y., Brulet P., Simeone A. Epilepsy and brain abnormalities in mice lacking the Otx1 gene. Nat. Genet. 14:1996;218-222.
2. Acampora D., Mazan S., Lallemand Y., Avantaggiato V., Maury M., Simeone A., Brulet P. Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation. Development. 121:1995;3279-3290.
3. Anderson D. J. Cellular and molecular biology of neural crest cell lineage determination. Trends Genet. 13:1997;276-280.
4. Bang A. G., Goulding M. D. Regulation of vertebrate neural cell fate by transcription factors. Curr. Opin. Neurobiol. 6:1996;25-32.
5. Chen C. Y., Schwartz R. J. Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription. Mol. Cell. Biol. 16:1996;6372-6384.
6. Copeland J. W., Nasiadka A., Dietrich B. H., Krause H. M. Patterning of the Drosophila embryo by a homeodomain-deleted Ftz polypeptide. Nature. 379:1996;162-165.
7. Dahl E., Koseki H., Balling R. Pax genes and organogenesis. BioEssays. 19:1997;755-765.
8. Franco del Amo F., Gendron-Maguire M., Swiatek P. J., Gridley T. Cloning, sequencing and expression of the mouse mammalian achaete-scute homolog 1 (MASH1). Biochim. Biophys. Acta. 1171:1993;323-327.
9. Freund C., Horsford D. J., McInnes R. R. Transcription factor genes and the developing eye: A genetic perspective. Hum. Mol. Genet. 5:1996;1471-1488.
10. Freund C. L., Gregory-Evans C. Y., Furukawa T., Papaioannou M., Looser J., Ploder L., Bellingham J., Ng D., Herbrick J. A., Duncan A. Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor. Cell. 91:1997;543-553.
11. Furukawa T., Morrow E. M., Cepko C. L. Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation. Cell. 91:1997;531-541.
12. Grueneberg D. A., Natesan S., Alexandre C., Gilman M. Z. Human and Drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor. Science. 257:1992;1089-1095.
13. Guichet A., Copeland J. W., Erdelyi M., Hlousek D., Zavorszky P., Ho J., Brown S., Percival-Smith A., Krause H. M., Ephrussi A. The nuclear receptor homologue Ftz-F1 and the homeodomain protein Ftz are mutually dependent cofactors. Nature. 385:1997;548-552.
14. Hatanaka H. Nerve growth factor-mediated stimulation of tyrosine hydroxylase activity in a clonal rat pheochromocytoma cell line. Brain Res. 222:1981;225-233.
15. Hughes P., Dragunow M. Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system. Pharmacol. Rev. 47:1995;133-178.
16. Ishiguro H., Kim K. T., Joh T. H., Kim K. S. Neuron-specific expression of the human dopamine beta-hydroxylase gene requires both the cAMP-response element and a silencer region. J. Biol. Chem. 268:1993;17987-17994.
17. Ishiguro H., Yamada K., Ichino N., Nagatsu T. Identification and characterization of a novel phorbol ester-responsive DNA sequence in the 5′-flanking region of the human dopamine beta-hydroxylase gene. J. Biol. Chem. 273:1998;21941-21949.
18. Johnson K. R., Smith L., Johnson D. K., Rhodes J., Rinchik E. M., Thayer M., Lewis E. J. Mapping of the ARIX homeodomain gene to mouse chromosome 7 and human chromosome 11q13. Genomics. 33:1996;527-531.
19. Kastury K., Druck T., Huebner K., Barletta C., Acampora D., Simeone A., Faiella A., Boncinelli E. Chromosome locations of human EMX and OTX genes. Genomics. 22:1994;41-45.
20. Kim H. S., Seo H., Yang C., Brunet J. F., Kim K. S. Noradrenergic-specific transcription of the dopamine beta-hydroxylase gene requires synergy of multiple cis-acting elements including at least two Phox2a-binding sites. J. Neurosci. 18:1998;8247-8260.
21. Kim J. S., Chae H. D., Joh T. H., Kim K. T. Stimulation of human DBH gene expression by prostaglandin E2 in human neuroblastoma SK-N-BE(2)C cells. J. Mol. Neurosci. 9:1997;143-150.
22. Kim K. S., Ishiguro H., Tinti C., Wagner J., Joh T. H. The cAMP-dependent protein kinase regulates transcription of the dopamine beta-hydroxylase gene. J. Neurosci. 14:1994;7200-7207.
23. Lumsden A., Krumlauf R. Patterning the vertebrate neuraxis. Science. 274:1996;1109-1115.
24. Morin X., Cremer H., Hirsch M. R., Kapur R. P., Goridis C., Brunet J. F. Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a. Neuron. 18:1997;411-423.
25. Pattyn A., Morin X., Cremer H., Goridis C., Brunet J. F. Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Development. 124:1997;4065-4075.
26. Shaskus J., Greco D., Asnani L. P., Lewis E. J. A bifunctional genetic regulatory element of the rat dopamine beta-hydroxylase gene influences cell type specificity and second messenger-mediated transcription. J. Biol. Chem. 267:1992;18821-18830.
27. Simeone A., Acampora D., Mallamaci A., Stornaiuolo A., D'Apice M. R., Nigro V., Boncinelli E. A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo. EMBO J. 12:1993;2735-2747.
28. Simon K. J., Grueneberg D. A., Gilman M. Protein and DNA contact surfaces that mediate the selective action of the Phox1 homeodomain at the c-fos serum response element. Mol. Cell. Biol. 17:1997;6653-6662.
29. Swanson D. J., Zellmer E., Lewis E. J. The homeodomain protein Arix interacts synergistically with cyclic AMP to regulate expression of neurotransmitter biosynthetic genes. J. Biol. Chem. 272:1997;27382-27392.
30. Swanson D. J., Zellmer E., Lewis E. J. AP1 proteins mediate the cAMP response of the dopamine beta-hydroxylase gene. J. Biol. Chem. 273:1998;24065-24074.
31. Takahashi E., Hori T., O'Connell P., Leppert M., White R. R-banding and nonisotopic in situ hybridization: Precise localization of the human type II collagen gene (COL2A1). Hum. Genet. 86:1990;14-16.
32. Takahashi E., Hori T., O'Connell P., Leppert M., White R. Mapping of the MYC gene to band 8q24.12-q24.13 by R-banding and distal to fra(8)(q24.11), FRA8E, by fluorescence in situ hybridization. Cytogenet. Cell. Genet. 57:1991;109-111.
33. Tiveron M. C., Hirsch M. R., Brunet J. F. The expression pattern of the transcription factor Phox2 delineates synaptic pathways of the autonomic nervous system. J. Neurosci. 16:1996;7649-7660.
34. Trask B. J. DNA sequence localization in metaphase and interphase cells by fluorescence in situ hybridization. Methods Cell. Biol. 35:1991;3-35.
35. Trask B. J., Massa H., Kenwrick S., Gitschier J. Mapping of human chromosome Xq28 by two-color fluorescence in situ hybridization of DNA sequences to interphase cell nuclei. Am. J. Hum. Genet. 48:1991;1-15.
36. Valarche I., Tissier-Seta J. P., Hirsch M. R., Martinez S., Goridis C., Brunet J. F. The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype. Development. 119:1993;881-896.
37. Yang C., Kim H. S., Seo H., Kim C. H., Brunet J. F., Kim K. S. Paired-like homeodomain proteins, Phox2a and Phox2b, are responsible for noradrenergic cell-specific transcription of the dopamine beta-hydroxylase gene. J. Neurochem. 71:1998;1813-1826.
38. Yokoyama M., Nishi Y., Miyamoto Y., Nakamura M., Akiyama K., Matsubara K., Okubo K. Molecular cloning of a human neuroD from a neuroblastoma cell line specifically expressed in the fetal brain and adult cerebellum. Brain Res. Mol. Brain Res. 42:1996a;135-139.
39. Yokoyama M., Nishi Y., Yoshii J., Okubo K., Matsubara K. Identification and cloning of neuroblastoma-specific and nerve tissue-specific genes through compiled expression profiles. DNA Res. 3:1996b;311-320.
40. Yu Y., Li W., Su K., Yussa M., Han W., Perrimon N., Pick L. The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Ftz. Nature. 385:1997;552-555.
41. Zellmer E., Zhang Z., Greco D., Rhodes J., Cassel S., Lewis E. J. A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes. J. Neurosci. 15:1995;8109-8120.